KCl flux-assisted CaTiO3: Pr3+ red phosphors for temperature sensing

Xin Liu,Xiuying Tian,Huiyan Sheng,Changyan Ji,Zhi Huang,Jin Wen,Hongxia Peng,Ling Zhu,Jing Li,Ping Liu,Yangxi Peng,Guowen Li 한양대학교 청정에너지연구소 2024 Journal of Ceramic Processing Research Vol.25 No.2

The red CaTiO3: Pr3+ phosphors were fabricated by employing a solid-state method using KCl flux, and investigated fortemperature sensing. There were no structural changes observed with increasing KCl concentration, and no impuritieswere detected. The obtained crystal structure was identified as an orthorhombic perovskite, belonging to space group ofPnma(62). The typical sample exhibited spherical particles (1-2 μm). The optical bandgap of the sample was measured to beapproximately 3.62 eV. Notably, when the KCl concentration reached 3%, the sample exhibited the highest photoluminescenceintensity, indicating excellent crystallization strength. They closely resembled the chromaticity coordinates of ideal red lightbased on CIE chromaticity diagram, and the color purity was determined to be 79.51%. Furthermore, the absolute sensitivity(Sa) was approximately as high as 0.148 K-1, while the relative sensitivity (Sr) reached approximately a high value of 6.57% K-1,which highlights the significant potential of optical thermometry.

Influence of Diffuser Vane Number on Energy Loss of Multistage Centrifugal Pump

Tian Xin Wu,Deng Hao Wu,Ting Zhang,Hai Ming Huang,Yue Zhong Wu,Jie Gang Mou 한국유체기계학회 2021 International journal of fluid machinery and syste Vol.14 No.4

As a key component of a multistage pump, the diffuser affects the efficiency of the multistage centrifugal pump. However, the loss mechanism inside the diffuser and links between the loss mechanism and vane numbers of diffuser were still not fully understood. In order to investigate the influence of the number of diffuser vane on the energy loss characteristics of multistage centrifugal pump, this paper analyzes the energy loss characteristics of pump with different number of diffuser vane by utilizing entropy production theory. The results show that under the design condition, when the number of diffuser vane increases to 11, the head is increased by 1.2m and the efficiency is increased by 3%. At the same time, with the increase of the number of diffuser vane, the backflow and eddy phenomena are gradually weakened, flow stream is more stable, the entropy production rate is significantly reduced, but the intensity of pressure pulsation in the diffuser is increased slightly.

Systematic Analysis of Pemetrexed-based Chemoradiotherapy for Patients with Locally Advanced or Metastatic Esophageal Cancer

Tian, Guang-Yu,Miu, Min,Huang, Xin-En Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

Purpose: This systematic analysis was conducted to evaluate the efficacy and safety of pemetrexed-based chemoradiotherapy in treating patients with locally advanced or metastatic esophageal cancer. Methods: Clinical studies evaluating the efficacy and safety of pemetrexed based regimens on response and safety for relevant patients were identified using a predefined search strategy. Pooled response rates (RRs) were calculated. Results: For pemetrexed-based regimens, 4 clinical studies including 47 patients with locally advanced or metastatic esophageal cancer were considered eligible for inclusion. Systematic analysis showed that, in all patients, the pooled RR was 51% (24/47). Major adverse effects of grade III/IV were esophagitis, neutropenia, thrombocytopenia, anemia anorexia, fatigue, diarrhea, dysphagia and vomiting. No treatment related death occurred with pemetrexed-based treatment. Conclusion: This systematic analysis suggests that pemetrexed based radiotherapy is associated with reasonable activity and good tolerability in treating patients with locally advanced or metastatic esophageal cancer.

Pemetrexed as a Component of First-, Second- and Third-line Chemotherapy in Treating Patients with Metastatic Lung Adenocarcinoma

Huang, Xin-En,Tian, Guang-Yu,Cao, Jie,Xu, Xia,Lu, Yan-Yan,Wu, Xue-Yan,Liu, Jin,Shi, Lin,Xiang, Jin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Purpose: The current research was conducted to investigate the efficacy and safety of pemetrexed given continuously as a basement agent for first-, second- to third line chemotherapy of patients with metastatic lung adenocarcinoma. Patients and Methods: Patients with metastatic lung adenocarcinoma who were diagnosed in Jiangsu Cancer Hospital and Research Insitute, were enrolled. All received pemetrexed 500 $mg/m^2$ (intravenous; on day 1), and another chemotherapieutic agent every 3 weeks until disease progression, or intolerable toxicity. Then the patients were changed to a second line chemotherapy that was still based on pemetrexed 500 $mg/m^2$ and another chemotherapeutic agent differing from the first line example, until disease progression, or intolerable toxicity. When third line chemotherapy was needed, pemetrexed 500 $mg/m^2$ and another new chemotherapeutic agent were combined until disease progression. Evaluation of efficacy was conducted after two cycles of chemotherapy using the Response Evaluation Criteria for Solid Tumors. Toxicity was recorded according to NCI Criteria for Adverse Events version 3.0. Results: From January 2010 to September 2013, 15 patients were enrolled. Their median age was 56 years (range 43 to 77 years). Eight patients were male and 7 female. Five patients (33.3%) achieved PR, while 6 patients (40.0%) remained stable, no CR on first line; and 1 PR (7.7%), 5 stable (38.5%) were recorded when pemetrexed was ordered in second line; 5 patients (41.7%) were stable after pemetrexed was combined in third line; no complete response was observed. Main side effects were grade 1 to 2 neutrophil suppression and thrombocytopenia. Other toxicities included elevated transaminase and oral mucositis, but no treatment related death occurred. Conclusions: Pemetrexed continuously as a basement agent from first-, second- to third line chemotherapy is mildly effective in treating patients with metastatic lung adenocarcinoma with tolerable toxicity.

Experimental Study on the Mechanism of Intermittent Water and Mud Inrush Caused by Dredging and Rainfall considering Sedimentary Characteristics in Karst Tunnels

Xin Huang,Tong Wang,Zhenhao Xu,Zhengguo Zhu,Jiaqi Guo,Peng Lin,Yongchao Tian 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.5

The mechanism of intermittent water and mud inrush is a difficult problem faced by disaster prevention and safe construction in karst tunnels. Aiming at revealing the mechanism of intermittent water and mud inrush, we developed an integrated testing system for filling medium deposition in karst caves and intermittent water and mud inrush. By conducting a serial of laboratory experiments, we analyzed the sedimentary characteristics of the filling medium in karst caves and the catastrophic process of intermittent water and mud inrush induced by dredging and rainfall under realistic sedimentary conditions. The results show that the filling medium exhibits layered deposition characteristics, which are affected by the water circulation time, the amount of sediments carried by water and the water flow rate. The first inrush incubation time reduces with the water head increases. The critical water head and the disaster incubation time increase with the deposition height increases. Under the same conditions, the first inrush incubation time of gravel type, silt type, and clay type filling medium decrease sequentially. The results can provide a theoretical basis for preventing intermittent water and mud inrush disasters in karst tunnels.

Simulation of the hydraulic isolation efficiency during multistage hydrajet fracturing

Xin Fan,Gensheng Li,Zhongwei Huang,Shouceng Tian,Xianzhi Song,Chen Yang 한국자원공학회 2015 Geosystem engineering Vol.18 No.5

Effective isolation between target zones is critical to multistage fracturing. Low pressure zone caused by the hydrajet is used to isolate stages in the multistage hydrajet fracturing technology. However, there are few researches available in the literature that investigates the hydraulic isolation efficiency considering the existence of multiple fractures. This paper builds a three-dimensional computational-fluid-dynamics model with FLUENT software to study the flow field along annular sections under different conditions. It is verified that the results obtained from the model are consistent with experimental data along the perforation tunnel. The mass flow rate ratio between two outlets is proposed to analyze the hydraulic isolation efficiency in hydrajet multistage fracturing. The results show that annular fluid converges into the perforation tunnel due to the high-speed hydrajet even though there is a pre-existing fracture behind. Effective hydraulic isolation can be generated by reducing the pressure differences between target zones and the annular injection velocity as well as by enlarging the jet velocity and the area ratio. It is found that there exists an optimum area ratio to get the maximum isolation efficiency. Sensitivity analysis indicates the pressure difference is the dominant factor affecting the hydraulic isolation efficiency. A fully quadratic model derived from the response surface method is presented to predict the hydraulic isolation efficiency for real fracturing. This study will be able to provide practical guidance for the optimization of hydrajet multistage fracturing.

Trends in Nasopharyngeal Carcinoma Mortality in China, 1973-2005

Huang, Tian-Ren,Zhang, Si-Wei,Chen, Wan-Qing,Deng, Wei,Zhang, Chun-Yan,Zhou, Xin-Juan,Zhai, Ri-Hong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

Nasopharyngeal carcinoma (NPC) is a disease with distinct ethnic and geographic distribution. The incidence of NPC in Chinese residing in Asia has declined over the last few decades, but NPC mortality trends in the entire Chinese population over time have not been systematically evaluated. In this study, we examined NPC mortality at the national level in China between 1973-2005. Mortality rates were derived from the databases of national retrospective surveys on cancer mortality conducted in the periods of 1973-1975, 1990-1992, and 2004-2005, respectively. NPC was classified according to the International classification of diseases. Age-adjusted mortality rates were calculated by direct standardization according to the world standard population. Trends in rates were evaluated by age, gender, geographic areas, and socioeconomic status. From 1973 to 2005, there was a general trend of decrease in NPC mortality in China, with higher rates in the south on a downward trend in the north. The age-standardized NPC mortality rates were 2.60 per 100,000 in 1973-1975, 1.94 per 100,000 in 1990-1992, and 1.30 per 100,000 in 2004-2005, respectively. The trend was similar in both men and women, in both urban and rural areas, but the declining rates in females were more remarkable than in males. The mortality rates were higher for the age groups above 50 years than those less than 50 years of age, both showing downward trend over 30-year period. In summary, the overall NPC mortality has consistently decreased in China over the past three decades, particularly in women and in old adults.

Enhanced photoluminescence from KCl flux assisted Eu3+ doped CaTiO3 red phosphor for temperature sensing

Xiuying Tian,Lei Li,Mengyuan Wei,Changyan Ji,Zhi Huang,Xin Liu,Jin Wen,Yangxi Peng 한양대학교 세라믹연구소 2021 Journal of Ceramic Processing Research Vol.22 No.5

CaTiO3: Eu3+ red phosphors with high thermal stability and temperature sensitivity were synthesized by KCl flux assisted solidphase reaction method and they had orthorhombic perovskite phase. CaTiO3:15%Eu3+ had the irregular particle structure,with mean particle size of about 1.58 μm, while CaTiO3:15%Eu3+ +6%KCl also had the irregular particle structure, with meanparticle size of about 2.25 μm. When Eu3+ ion concentration was 15mol%, concentration quenching phenomenon took place,which could be explained by electric dipole-dipole interaction due to the critical Eu3+- Eu3+ distance of ~ 8.93 Å. We found thatKCl flux could increase the particle size and crystallinity, which was beneficial to luminescence property. Based on the PLspectra excited at 398 nm, the color coordinates of CaTiO3:15%Eu3+ were (0.5911, 0.4008) and the color purity was 97.7%,while the color coordinates of sample CaTiO3:15%Eu3++ 6%KCl were (0.6042, 0.3895) and the color purity was 98.4%. Therelative intensity IR1 and IR2 at 423 K is 87. 29% and 83. 22%, indicating the sample had high thermal stability. Based on TCLsFIR, Sr of CaTiO3:15%Eu3+ is 2322.67/T^2. CaTiO3:Eu3+ red phosphor was expected to be a promising inorganic material forpossible applications in temperature sensing.

Polysaccharide of Atractylodes macrocephala Koidz Enhances Cytokine Secretion by Stimulating the TLR4–MyD88–NF-κB Signaling Pathway in the Mouse Spleen

Bing-Xin Li,Wan-Yan Li,Yun-Bo Tian,Si-Xuan Guo,Yun-Mao Huang,Dan-Ning Xu,Nan Cao 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.9

Polysaccharide of Atractylodes macrocephala Koidz (PAMK) has been reported to have beneficial effects on regulation of immune responses in mammals and poultry. Nonetheless, the immunoregulatory mechanism of action of PAMK remains unclear. The Toll-like receptor 4 (TLR4) signaling cascade has been proved as a classic polysaccharide-regulated pathway. The aim of this study was to explore the effects of PAMK on the TLR4 signaling pathway in the regulation of spleen function in mice. Ninety-six 5-week-old BALB/c female mice were randomly allocated into four groups with three replicates per group and eight mice per replicate in a single-factor completely randomized experimental design. The control group was fed a basic diet (PAMK free); the other three groups were fed 100, 200, or 400 mg/kg PAMK for 28 days. The spleen index, concentrations of cytokines, and mRNA and protein expression levels of genes related to TLR4 signaling were determined in spleen tissue. Compared with the control group, the spleen index significantly increased in all treatment groups. Concentrations of interleukin 2 (IL-2), IL-4, interferon γ (IFN-γ), and tumor necrosis factor α (TNF-α) in the medium-PAMK group also increased significantly. PAMK in the medium-PAMK group significantly increased both mRNA and protein expression of TLR4, myeloid differentiation factor 88 (MyD88), TNFR-associated factor 6 (TRAF6), TRAF3, and nuclear factor kappa B (NF-κB) in the spleen. In conclusion, PAMK may increase immune-response capacity of the spleen in mice via TLR4–MyD88–NF-κB signaling.

Cavitation Diagnosis Method for Centrifugal Pumps based on Agglomerative Hierarchical Clustering Algorithm

Hai Ming Huang,Yan Liu,Denghao Wu,Yue Zhong Wu,Tian Xin Wu 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.1

Cavitation in the pump induces vibration and noise, which leads to the degradation of pump performance and damage to the impeller. Therefore, it is of great significance to accurately identify the cavitation state of the centrifugal pump. To determine the cavitation state using the vibration characteristic frequency of the centrifugal pump, it is necessary to accurately identify the characteristic frequency due to the noise's effect. Therefore, a cavitation fault diagnosis method of centrifugal pump based on a cohesive hierarchy algorithm was proposed. Firstly, Singular Value Decomposition (SVD) is used to de-noise the vibration signal. Then the root means square of the vibration signal after de-noising is obtained as the eigenvalue of the vibration signal. Secondly, the hierarchical clustering algorithm is used to classify the vibration eigenvalues and accurately identify the non-cavitation and cavitation states of centrifugal pumps. Finally, through experimental tests, the method can effectively and quickly identify the cavitation state of the centrifugal pump, with an accuracy of 95%. The study provides a new way for rapidly diagnosing centrifugal pump cavitation