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        Effect of Pressure on the Field-induced Ordered Phase in the Heavy-fermion Compound YbCo2Zn20

        Tetsuya Takeuchi,Yuki Taga,Shingo Yoshiuchi,Masahiro Ohya,Yusuke Hirose,Fuminori Honda,Rikio Settai,Yoshichika Onuki 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12

        The effect of pressure on the field-induced ordered phase for H k h111i in the heavy-fermioncompound YbCo2Zn20, which is presumably a field-induced antiferro-quadrupolar (FI-AFQ) phase,was investigated in the pressure range up to 4.5 GPa and under magnetic fields up to 80 kOe. When pressure is applied, the metamagnetic-like transition at Hm =6 kOe shifts to lower fieldsand disappears around the quantum critical pressure Pc 1.8 GPa. A pressure-induced antiferromagnetic(PI-AFM) phase appears at pressures above about 2 GPa, and the critical field Hc ofthe PI-AFM phase increases with increasing pressure. On the other hand, the transition field HQof the FI-AFQ phase decreases gradually without showing any anomalous behavior around Pc andbecomes obscure around 4 GPa, where Hc of the PI-AFM phase and HQ of the FI-AFQ phasebecome comparable. The magnetic field versus pressure, H-P, phase diagram for H k h111i at0.1 K was constructed in the pressure range up to 4.5 GPa.

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        Sry-related High Mobility Group Box 17 Functions as a Tumor Suppressor by Antagonizing the Wingless-related Integration Site Pathway

        Maha Anani,Ikuo Nobuhisa,Tetsuya Taga 대한암예방학회 2020 Journal of cancer prevention Vol.25 No.4

        A transcription factor Sry-related high mobility group box (Sox) 17 is involved in developmental processes including spermatogenesis, cardiovascular system, endoderm formation, and so on. In this article, we firstly review the studies on the relation between the Sox17 expression and tumor malignancy. Although Sox17 positively promotes various tissue development, most of the cancers associated with Sox17 show decreased expression levels of Sox17, and an inverse correlation between Sox17 expression and malignancy is revealed. We briefly discuss the mechanism of such Sox17 down-regulation by focusing on DNA methylation of CpG sites located in the Sox17 gene promoter. Next, we overview the function of Sox17 in the fetal hematopoiesis, particularly in the dorsal aorta in midgestation mouse embryos. The Sox17 expression in hematopoietic stem cell (HSC)-containing intra-aortic hematopoietic cell cluster (IAHCs) is important for the cluster formation with the hematopoietic ability. The sustained expression of Sox17 in adult bone marrow HSCs and the cells in IAHCs of the dorsal aorta indicate abnormalities that are low lymphocyte chimerism and the aberrant proliferation of common myeloid progenitors in transplantation experiments. We then summarize the perspectives of Sox17 research in cancer control. Key Words Transcription factors, Neoplasms, Methylation, Hematopoiesis, Aotra

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