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Plasmodium falciparum apicoplast and its transcriptional regulation through calcium signaling
Praveen Rai,Drista Sharma,Rani Soni,Nazia Khatoon,Bhaskar Sharma,Tarun Kumar Bhatt 한국미생물학회 2017 The journal of microbiology Vol.55 No.4
Malaria has been present since ancient time and remains amajor global health problem in developing countries. Plasmodiumfalciparum belongs to the phylum Apicomplexan,largely contain disease-causing parasites and characterizedby the presence of apicoplast. It is a very essential organelleof P. falciparum responsible for the synthesis of key moleculesrequired for the growth of the parasite. Indispensablenature of apicoplast makes it a potential drug target. Calciumsignaling is important in the establishment of malaria parasiteinside the host. It has been involved in invasion and egressof merozoites during the asexual life cycle of the parasite. Calcium signaling also regulates apicoplast metabolism. Therefore,in this review, we will focus on the role of apicoplast inmalaria biology and its metabolic regulation through Ca++signaling.
Singh, Harvinder,Prashar, Sanjeev,Agarwal, Rashmi,Sharma, Tarun Kumar KNU The Institute of Management Economy Research 2014 Asia-Pacific Journal of Business Vol.5 No.1
Shopping malls have become key players in the Indian retail space. Even in upcoming Indian towns, malls have been mushrooming. Raipur, the capital city of the Indian state of Chhattisgarh has witnessed the growth over the last few years. However, this unplanned growth of malls in cities is expected to lead to oversupply of mall space in the near future, making things difficult for mall developers. The study is an attempt to identify appropriate strategies for mall developers to iron out such kinks. This paper presents 'shopping experience' as a tool to compete, succeed and explore its composition in terms of its constituent factors. The paper uses Exploratory Factor Analysis (EFA) on a non-probability sample of 350 respondents. It condenses a set of twenty-two mall variables into five factors that directly influence the shopping experience. These factors included ambience, infrastructure, marketing focus, convenience and safety and security. In terms of significance, shoppers assigned different weightage to each of these factors. The study shed light on interesting insights regarding the expectations of mall shoppers in the city of Raipur. The results though interesting, may be extended to different social, economic and geographic contexts to check the universality. While strategizing, mall developers must assign proportionate effort on the factors based on the respective contribution to shopping experience. In light of intensifying competition in Raipur, the study is significant for future prospects of malls. In the absence of a scientific and objective basis, the developers run risk of making wrong investment and management decisions. This paper is a useful addition to the body of knowledge on management of shopping malls in India and is unique in terms of its focus on mall shoppers in the smaller Indian cities like Raipur.
Determinants of Shopping Experience for Mall Shoppers
Harvinder Singh,Sanjeev Prashar,Rashmi Agarwal,Tarun Kumar Sharma 강원대학교 경영경제연구소 2014 Asia-Pacific Journal of Business Vol.5 No.1
Shopping malls have become key players in the Indian retail space. Even in upcoming Indian towns, malls have been mushrooming. Raipur, the capital city of the Indian state of Chhattisgarh has witnessed the growth over the last few years. However, this unplanned growth of malls in cities is expected to lead to oversupply of mall space in the near future, making things difficult for mall developers. The study is an attempt to identify appropriate strategies for mall developers to iron out such kinks. This paper presents ‘shopping experience’ as a tool to compete, succeed and explore its composition in terms of its constituent factors. The paper uses Exploratory Factor Analysis (EFA) on a non-probability sample of 350 respondents. It condenses a set of twenty-two mall variables into five factors that directly influence the shopping experience. These factors included ambience, infrastructure, marketing focus, convenience and safety and security. In terms of significance, shoppers assigned different weightage to each of these factors. The study shed light on interesting insights regarding the expectations of mall shoppers in the city of Raipur. The results though interesting, may be extended to different social, economic and geographic contexts to check the universality. While strategizing, mall developers must assign proportionate effort on the factors based on the respective contribution to shopping experience. In light of intensifying competition in Raipur, the study is significant for future prospects of malls. In the absence of a scientific and objective basis, the developers run risk of making wrong investment and management decisions. This paper is a useful addition to the body of knowledge on management of shopping malls in India and is unique in terms of its focus on mall shoppers in the smaller Indian cities like Raipur.