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      • KCI등재

        Phylogeny of a Novel “Helicobacter heilmannii” Organism from a Japanese Patient with Chronic Gastritis Based on DNA Sequence Analysis of 16S rRNA and Urease Genes

        Takehisa Matsumoto,Masatomo Kawakubo,Mayumi Shiohara,Toshiko Kumagai,Eiko Hidaka,Kazuyoshi Yamauchi,Kozue Oana,Kenji Matsuzawa,Hiroyoshi Ota,Yoshiyuki Kawakami 한국미생물학회 2009 The journal of microbiology Vol.47 No.2

        “Helicobacter heilmannii” is an uncultivable spiral-shaped bacterium inhabiting the human gastric mucosa. It is larger and more tightly-coiled than H. pylori. We encountered a patient with chronic gastritis infected a “H. heilmannii”-like organism (HHLO), designated as SH6. Gastric mucosa derived from the patient was orally ingested by specific pathogen free mice. Colonization of the mice by SH6 was confirmed by electron microscopy of gastric tissue specimens. In an attempt to characterize SH6, 16S rRNA and urease genes were sequenced. The 16S rRNA gene sequence was most similar (99.4%; 1,437/1,445 bp) to HHLO C4E from a cheetah. However, the urease gene sequence displayed low similarity (81.7%; 1,240/1,516 bp) with HHLO C4E. Taxonomic analysis disclosed that SH6 represents a novel strain and should constitute a novel taxon in the phylogenetic trees, being discriminated from any other taxon, with the ability of infecting human gastric mucosa.

      • Reliability Analysis of Interconnected Dynamical Systems with Reconfigurable Control

        Matsumoto, Satoshi,Kohda, Takehisa The Korean Society of Safety 2011 International Journal of Safety Vol.10 No.2

        The reconfigurable control systems based on feedback controls are utilized to compensate for damages of actuators in control systems. Such systems have multiple feedback controls and switch them in accordance with the degrees of the failures of the actuators. In order to be able to assess those systems, this paper develops a method to obtain reliabilities of reconfigurable dynamical systems which are interconnected in parallel / series configuration. By calculating reliabilities of interconnected dynamical systems, it is possible to assess many dynamical systems by comparing their reliabilities. Firstly, reliabilities of subsystems are obtained according to the definitions of the failures in terms of robust reliability for each subsystem. Then, the reliability of overall system is calculated from reliabilities of subsystems, using the methodology employed for probabilistic safety assessment. Failure rates of subsystems with feedbacks for reconfiguration change in certain time periods because of the switching of feedback controls. In order to deal with this, combinations of subsystems which compose overall system for each time period are derived by the methodology mentioned above and then integrated to calculate the reliability of overall system for a specific time. An illustrative example shows the validity and details of the proposed method.

      • Reliability Analysis of Interconnected Dynamical Systems with Reconfigurable Control

        ( Satoshi Matsumoto ),( Takehisa Kohda ) 한국안전학회(구 한국산업안전학회) 2011 International Journal of Safety Vol.10 No.2

        The reconfigurable control systems based on feedback controls are utilized to compensate for damages of actuators in control systems. Such systems have multiple feedback controls and switch them in accordance with the degrees of the failures of the actuators. In order to be able to assess those systems, this paper develops a method to obtain reliabilities of reconfigurable dynamical systems which are interconnected in parallel / series configuration. By calculating reliabilities of interconnected dynamical systems, it is possible to assess many dynamical systems by comparing their reliabilities. Firstly, reliabilities of subsystems are obtained according to the definitions of the failures in terms of robust reliability for each subsystem. Then, the reliability of overall system is calculated from reliabilities of subsystems, using the methodology employed for probabilistic safety assessment. Failure rates of subsystems with feedbacks for reconfiguration change in certain time periods because of the switching of feedback controls. In order to deal with this, combinations of subsystems which compose overall system for each time period are derived by the methodology mentioned above and then integrated to calculate the reliability of overall system for a specific time. An illustrative example shows the validity and details of the proposed method.

      • KCI등재

        Observation of disossiative recombination in the hydrogen sheet plasma

        akira Tonegawa,Hiroie MATSUMOTO,Hiroyuki YAZAWA,Kazutaka KAWAMURA,Masataka ONO,Takehisa SHIBUYA 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III

        The experimental observation of dissociative recombination in Molecular Assisted Recombination (MAR) for hydrogen detached plasma has been studied in the linear divertor plasma simulator, TPD-SheetIV. Measurements of the relative concentrations of atomic and molecular ions (nH+, n+ H2, and n+ H3), electron density (ne), electron temperature (Te), and heat load to the target plate (Q) were carried out in hydrogen detached plasma with hydrogen gas puff at varying discharge current. An “omegatron” mass analyzer, situated behind a small hole of the endplate, is used for analyzing ion species. It is shown from these results that the dominant molecular process is a dissociative recombination process via H+ 2 , H+ 3 in the plasma over the range of low plasma density (<5 × 1018 m.3) and low hydrogen pressure (<4 mTorr). In contrast, molecular assisted dissociation (MAD) always dominates over the MAR in the high density plasma (>5 × 1018 m.3).

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