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Band offsets and optical conduction in the CdSe/GaSe interface
T.S. Kayed,A.F. Qasrawi,Khaled A. Elsayed 한국물리학회 2016 Current Applied Physics Vol.16 No.7
In this work, the design and characterization of CdSe/GaSe heterojunction is considered. The CdSe/GaSe thin film interface was prepared by the physical vapor deposition technique. Systematic structural and optical analysis were performed to explore the crystalline nature, the optical band gaps, the conduction and valence band offsets, the dielectric spectra, and the frequency dependent optical conductivity at terahertz frequencies. The X-ray diffraction analysis revealed a polycrystalline interface that is mostly dominated by the hexagonal CdSe oriented in the (002) direction. It was also found that the CdSe/GaSe interface exhibits conduction and valence band offsets of 1.35 and 1.23/1.14 eV, respectively. The dielectric spectra displayed two dielectric resonance peaks at 530 and 445 THz. Moreover, the computational fittings of the optical conductivity of the interface revealed a free carrier scattering time of 0.41 (fs) for a free carrier density of 7.0 1018 (cm3). The field effect mobility for the CdSe/GaSe interface was found to be 5.22 (cm2/Vs). The remarkable features of this device having large band offsets and qualitative optical conduction dominated by a scattering time in the order of femtoseconds in addition to the dielectric property nominate the device to be used in optoelectronic technology.
Characterization of Au/As2Se3/MoO3/Ag hybrid devices designed for dual optoelectronic applications
T.S. Kayed,A.F. Qasrawi 한국물리학회 2020 Current Applied Physics Vol.20 No.1
In this work, hybrid devices composed of n As2Se3/p MoO3 encapsulated between two Schottky shoulders (Au/n-As2Se3, Ag/MoO3) are prepared and characterized. While the structural analyses proofed the preferred growth of monoclinic MoO3 onto amorphous layers of As2Se3, the spectroscopic ellipsometry analysis revealed the high frequency dielectric constants, the effective mass and the negative pseudodielectric constant values. Electrically, the hybrid device displayed both tunneling and standard diode characteristics. As passive mode devices, the capacitance-voltage characteristics displayed the accumulation-depletion -inversion modes in the device. Furthermore, the conductivity spectral analysis has shown that the current conduction is dominated by the quantum mechanical tunneling and correlated barriers hoping mechanisms. The amplitude of the reflection coefficient and the return loss spectral analyses indicated that the hybrid devices are band stop filters in addition to it is usability as nonlinear optical interfaces, CMOS device and tunneling diodes.
Report from IPITA-TTS Opinion Leaders Meeting on the Future of &bgr;-Cell Replacement
Bartlett, Stephen T.,Markmann, James F.,Johnson, Paul,Korsgren, Olle,Hering, Bernhard J.,Scharp, David,Kay, Thomas W. H.,Bromberg, Jonathan,Odorico, Jon S.,Weir, Gordon C.,Bridges, Nancy,Kandaswamy, R Wolters Kluwer Health, Inc. All rights reserved. 2016 Transplantation Vol.100 No.2
Kim, Y.,Choi, H.,Lee, W.,Park, H.,Kam, T.I.,Hong, S.h.,Nah, J.,Jung, S.,Shin, B.,Lee, H.,Choi, T.Y.,Choo, H.,Kim, K.K.,Choi, S.Y.,Kayed, R.,Jung, Y.K. Blackwell Science ; Academic Press 2016 Neurobiology of disease Vol.87 No.-
<P>In neurodegenerative diseases like AD, tau forms neurofibrillary tangles, composed of tau protein. In the AD brain, activated caspases cleave tau at the 421th Asp, generating a caspase-cleaved form of tau, TauC3. Although TauC3 is known to assemble rapidly into filaments in vitro, a role of TauC3 in vivo remains unclear. Here, we generated a transgenic mouse expressing human TauC3 using a neuron-specific promoter. In this mouse, we found that human TauC3 was expressed in the hippocampus and cortex. Interestingly, TauC3 mice showed drastic learning and spatial memory deficits and reduced synaptic density at a young age (2-3 months). Notably, tau oligomers as well as tau aggregates were found in TauC3 mice showing memory deficits. Further, i.p. or i.c.v. injection with methylene blue or Congo red, inhibitors of tau aggregation in vitro, and i.p. injection with rapamycin significantly reduced the amounts of tau oligomers in the hippocampus, rescued spine density, and attenuated memory impairment in TauC3 mice. Together, these results suggest that TauC3 facilitates early memory impairment in trans genic mice accompanied with tau oligomer formation, providing insight into the role of TauC3 in the AD pathogenesis associated with tau oligomers and a useful AD model to test drug candidates. (C) 2015 Elsevier Inc. All rights reserved.</P>
Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of &bgr;-Cell Replacement
Markmann, James F.,Bartlett, Stephen T.,Johnson, Paul,Korsgren, Olle,Hering, Bernhard J.,Scharp, David,Kay, Thomas W. H.,Bromberg, Jonathan,Odorico, Jon S.,Weir, Gordon C.,Bridges, Nancy,Kandaswamy, R Williams & Wilkins Co 2016 Transplantation Vol.100 No.7
SUMMARY: The International Pancreas and Islet Transplant Association (IPITA), in conjunction with the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.