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RISS 인기검색어
- 검색키워드
- 저자 : T. Venkatesan (검색결과 5 건)
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Venkatesan, T.,Choi, Y. W.,Mun, S. P.,Kim, Y. K. Springer Science + Business Media 2016 Cell biology and toxicology Vol.32 No.5
<P>In the present study, we investigated the anticancer activity of Pinus radiata bark extract (PRE) against MCF-7 human breast cancer cells. First, we observed that PRE induces potent cytotoxic effects in MCF-7 cells. The cell death had features of cytoplasmic vacuolation, plasma membrane permeabilization, chromatin condensation, phosphatidylserine externalization, absence of executioner caspase activation, insensitivity to z-VAD-fmk (caspase inhibitor), increased accumulation of autophagic markers, and lysosomal membrane permeabilization (LMP). Both the inhibition of early stage autophagy flux and lysosomal cathepsins did not improve cell viability. The antioxidant, n-acetylcysteine, and the iron chelator, deferoxamine, failed to restore the lysosomal integrity indicating that PRE-induced LMP is independent of oxidative stress. This was corroborated with the absence of enhanced ROS production in PRE-treated cells. Chelation of both intracellular calcium and zinc promotes PRE-induced LMP. Geranylgeranylacetone, an inducer of Hsp70 expression, also had no significant protective effect on PRE-induced LMP. Moreover, we found that PRE induces endoplasmic reticulum (ER) stress and mitochondrial membrane depolarization in MCF-7 cells. The ER stress inhibitor, 4-PBA, did not restore the mitochondrial membrane integrity, whereas cathepsin inhibitors demonstrated significant protective effects. Collectively, our results suggest that PRE induces an autophagic block, LMP, ER stress, and mitochondrial dysfunction in MCF-7 cells. However, further studies are clearly warranted to explore the exact mechanism behind the anticancer activity of PRE in MCF-7 human breast cancer cells.</P>
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A Novel Image Encryption Using Calligraphy Based Scan Method and Random Number
( T Sivakumar ),( R Venkatesan ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.6
Cryptography provides an effective solution to secure the communication over public networks. The communication over public networks that includes electronic commerce, business and military services, necessitates the requirement of simple and robust encryption techniques. In this paper, a novel image encryption method which employs calligraphy based hybrid scan and random number is presented. The original image is scrambled by pixel position permutation with calligraphy based diagonal and novel calligraphy based scan patterns. The cipher image is obtained by XORing the scrambled image with random numbers. The suggested method resists statistical, differential, entropy, and noise attacks which have been demonstrated with a set of standard images.
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Research and Experimental Implementation of a CV-FOINC Algorithm Using MPPT for PV Power System
Arulmurugan, R,Venkatesan, T 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.4
This research suggests maximum power point tracking (MPPT) for the solar photovoltaic (PV) power scheme using a new constant voltage (CV) fractional order incremental conductance (FOINC) algorithm. The PV panel has low transformation efficiency and power output of PV panel depends on the change in weather conditions. Possible extracting power can be raised to a battery load utilizing a MPPT algorithm. Among all the MPPT strategies, the incremental conductance (INC) algorithm is mostly employed due to easy implementation, less fluctuations and faster tracking, which is not only has the merits of INC, fractional order can deliver a dynamic mathematical modelling to define non-linear physiognomies. CV-FOINC variation as dynamic variable is exploited to regulate the PV power toward the peak operating point. For a lesser scale photovoltaic conversion scheme, the suggested technique is validated by simulation with dissimilar operating conditions. Contributions are made in numerous aspects of the entire system, including new control algorithm design, system simulation, converter design, programming into simulation environment and experimental setup. The results confirm that the small tracking period and practicality in tracking of photovoltaic array.
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N. Rajasekaran,C. Muniraj,T. Venkatesan,A. Kumaravel 한양대학교 청정에너지연구소 2024 Journal of Ceramic Processing Research Vol.25 No.1
Nanocomposites (LDPE + BaTiO3 ceramic) with different volume ratio of 0%, 1%, 3% and 5% were prepared by melt mixingmethod. Scanning Electron microscopy (SEM) results for nanocomposites materials shows that the nanofiller particle disperseduniformly throughout the entire surface and there is no agglomeration of nanoparticles. BaTiO3 ceramic nanoparticle structureand crystallite size were investigated using X-ray diffraction (XRD) studies. Using energy-dispersive X-ray spectroscopy (EDS),the chemical composition of the composite material has been determined. EDS can have determined the types of elementspresent in the sample and their relative concentrations. To assess the behavior of nanocomposites, experimental test wasconducted to predict the electrical parameters such as dielectric breakdown strength, DC volume resistivity, dielectric constantand Dissipation factor. The dielectric strength was estimated using a feed forward neural network (FFNN) and ArtificialNeural Network and Fuzzy Inference system (ANFIS) technique under various conditions and filler percentages. From the testresults, it was observed that nanocomposites with 3% wt has the highest dielectric strength. In Weibull analysis, feed forwardneural network (FFNN) and Artificial Neural Network and Fuzzy Inference system (ANFIS) predicted that with the inclusionof nanofiller, the electrical breakdown strength of nanocomposite materials was increased. The results show that, dielectricpermittivity and dissipation factor (tan delta) of the nanocomposites materials decreased and increased correspondingly withincrease in frequency. Further increase in mixing proportion of nanocomposites, it was found that the inter particle distanceis decreased due to that the mobility of charge carrier is increased and the material loses its dielectric property. From theexperimental test results, it was found that LDPE/BaTiO3 ceramic filler nanocomposites materials with 3% wt have betterelectrical properties compared to neat LDPE.
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Surface energy and wettability of van der Waals structures
Annamalai, M.,Gopinadhan, K.,Han, S.,Saha, S.,Park, H.,Cho, E.,Kumar, B.,Patra, A.,Kim, S. W.,Venkatesan, T. Royal Society of Chemistry 2016 Nanoscale Vol.8 No.10
<P>The wetting behaviour of surfaces is believed to be affected by van der Waals (vdW) forces; however, there is no clear demonstration of this. With the isolation of two-dimensional vdW layered materials it is possible to test this hypothesis. In this paper, we report the wetting behaviour of vdW heterostructures which include chemical vapor deposition (CVD) grown graphene, molybdenum disulfide (MoS2) and tungsten disulfide (WS2) on few layers of hexagon boron nitride (h-BN) and SiO2/Si. Our study clearly shows that while this class of two-dimensional materials are not completely wetting transparent, there seems to be a significant amount of influence on their wetting properties by the underlying substrate due to dominant vdW forces. Contact angle measurements indicate that graphene and graphene-like layered transitional metal dichalcogenides invariably have intrinsically dispersive surfaces with a dominating London-vdW force-mediated wettability.</P>
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