http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Suping Guo (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Tiantian Lian,Tao Yang,Junde Sun,Suping Guo,Huaijun Yang,Caihong Dong 한국미생물학회 2014 The journal of microbiology Vol.52 No.8
Cordyceps militaris, the type species of genus Cordyceps, isone of the most popular mushrooms and a nutraceutical ineastern Asia. It is considered a model organism for thestudy of Cordyceps species because it can complete its lifecycle when cultured in vitro. In the present study, the occurrenceand sequence variation of SSU rDNA group I introns,Cmi.S943 and Cmi.S1199, among different isolatesof C. militaris were analyzed. Based on the secondary structurepredictions, the Cmi.S943 intron has been placed insubgroup IC1, and the Cmi.S1199 intron has been placedin subgroup IE. No significant similarity between Cmi.S943and Cmi.S1199 suggested different origins. Three genotypes,based on the frequency and distribution of introns, were describedto discriminate the 57 surveyed C. militaris strains. It was found that the genotype was related to the stromacharacteristics. The stromata of all of the genotype II strains,which possessed only Cmi.S943, could produce perithecium. In contrast, the stromata of all genotype III strains, whichhad both Cmi.S943 and Cmi.S1199, could not produce perithecium. Cmi.S1199 showed the lowest level of intra-specificvariation among the tested strains. Group I introns can belost during strain cross-mating. Therefore, we presumed thatduring cross-mating and recombination, intron loss could bedriven by positive Darwinian selection due to the energeticcost of transcribing long introns.
-
Yingjia Wu,Jinbin Chen,Lei Zhao,Qiaoqiao Li,Jinhan Zhu,Hong Yang,Suping Guo,Mian Xi 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1
Purpose This study aimed to develop a nomogram for predicting pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) in patients with esophageal squamous cell carcinoma (ESCC) by integrating hematological biomarkers and clinicopathological characteristics. Materials and Methods Between 2003 and 2017, 306 ESCC patients who underwent neoadjuvant CRT followed by esophagectomy were analyzed. Besides clinicopathological factors, hematological parameters before, during, and after CRT were collected. Univariate and multivariate logistic regression analyses were performed to identify predictive factors for pCR. A nomogram model was built and internally validated. Results Absolute lymphocyte count (ALC), lymphocyte to monocyte ratio, albumin, hemoglobin, white blood cell, neutrophil, and platelet count generally declined, whereas neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) increased significantly following neoadjuvant CRT. After surgery, 124 patients (40.5%) achieved a pCR. The pCR group demonstrated significantly more favorable survival than the non-pCR group. On multivariate analysis, significant factors associated with pCR included sex, chemotherapy regimen, post-CRT endoscopic finding, pre-CRT NLR, ALC nadir during CRT, and post-CRT PLR, which were incorporated into the prediction model. The nomogram indicated good accuracy in predicting pCR, with a C-index of 0.75 (95% confidence interval, 0.71 to 0.78). Conclusion Female, chemotherapy regimen of cisplatin/vinorelbine, negative post-CRT endoscopic finding, pre-CRT NLR (≤ 2.1), ALC nadir during CRT (> 0.35×109/L), and post-CRT PLR (≤ 83.0) were significantly associated with pCR in ESCC patients treated with neoadjuvant CRT. A nomogram incorporating hematological biomarkers to predict pCR was developed and internally validated, showing good predictive performance.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
