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Prediction of Quantitative Traits Using Common Genetic Variants: Application to Body Mass Index
Bae, Sunghwan,Choi, Sungkyoung,Kim, Sung Min,Park, Taesung Korea Genome Organization 2016 Genomics & informatics Vol.14 No.4
With the success of the genome-wide association studies (GWASs), many candidate loci for complex human diseases have been reported in the GWAS catalog. Recently, many disease prediction models based on penalized regression or statistical learning methods were proposed using candidate causal variants from significant single-nucleotide polymorphisms of GWASs. However, there have been only a few systematic studies comparing existing methods. In this study, we first constructed risk prediction models, such as stepwise linear regression (SLR), least absolute shrinkage and selection operator (LASSO), and Elastic-Net (EN), using a GWAS chip and GWAS catalog. We then compared the prediction accuracy by calculating the mean square error (MSE) value on data from the Korea Association Resource (KARE) with body mass index. Our results show that SLR provides a smaller MSE value than the other methods, while the numbers of selected variables in each model were similar.
Unlimited Cooperative Sensing with Energy Detection for Cognitive Radio
Bae, Sunghwan,Kim, Hongseok The Korea Institute of Information and Commucation 2014 Journal of communications and networks Vol.16 No.2
In this paper, we investigate the fundamental performance limits of the cooperative sensing using energy detection by considering the unlimited number of sensing nodes. Although a lot of cognitive radio research so far proposed various uses of energy detection because of its simplicity, the performance limits of energy detection have not been studied when a large number of sensing nodes exist. First, we show that when the sensing nodes see the independent and identically distributed channel conditions, then as the number of sensing nodes N goes to infinity, the OR rule of hard decision achieves zero of false alarm Pf for any given target probability of detection $\bar{P_d}$ irrespective of the non-zero received primary user signal to noise ratio ${\gamma}$. Second, we show that under the same condition, when the AND rule of hard decision is used, there exists a lower bound of $P_f$. Interestingly, however, for given $\bar{P_d}$, $P_f$ goes to 1 as N goes to infinity. Third, we show that when the soft decision is used, there exists a way of achieving 100% utilization of secondary user, i.e., the sensing time overhead ratio goes to zero so does $P_f$.We verify our analyses by performing extensive simulations of the proposed unlimited cooperative sensing. Finally, we suggest a way of incorporating the unlimited cooperative sensing into a practical cellular system such as long term evolutionadvanced by exploiting the existing frame structure of absolute blank subframe to implement the in-band sensing.
시설하우스에서 퀀텀닷조명이 고추냉이 생육에 미치는 영향
배성환(Sunghwan Bae),유용환(Yong Hwan Yoo),신정철(Jung Chul Shin),김민하(Minha Kim),안효성(Hyo-Seong Ahn),박상운(Sang Un Park),김용득(Yongduk Kim) 한국조명·전기설비학회 2021 한국조명·전기설비학회 학술대회논문집 Vol.2021 No.11
Quantum dot is a particle with unique optical properties. Through electric current flows, generate light wavelengths of different lengths depending on the size of the particles. The LED made of quantum dot (QDLED) can control the light spectrum and has the potential to provide a light source optimized for the growth of individual species. According to this characteristeics fo QD-LED, this experiment was conducted to confirm the effects of QD-LED that based on absorption spectrum of wasabi on the growth and quality of Wasabi japonica ‘Daruma’. ‘Daruma’ seedling were cultivated in cheerwon Saemtong Gochuneangii greenhouse. The light source was composed of 3:1 ratio according to the light intensity of blue (B) and red (B) mixed. And as a control, only sun-treated wasabi was placed. At 11 weeks after planting, the plant length, petiole length, leaf length, leaf width, and number of leaves were compared. As a result, QD-LED light were shown significant differences at all characteristeics. In summary, compared to the sunlight, the QD-LED is advantageous for the growth of five quantitative traits of wasabi japonica ‘Daruma’. The rhizome weight of wasabi is highly positively correlated with the No. of leaves on main rhizome, inducing an increase in the number of leaves through the QD-LED light source is expected to increase the yield of wasabi.
Bae, EunJung,Yeo, In Joon,Jeong, Byungkwan,Shin, Yongsik,Shin, Kyung-Hoon,Kim, Sunghwan American Chemical Society 2011 ANALYTICAL CHEMISTRY - Vol.83 No.11
<P>A strong linear relationship was observed between the average double bond equivalence (DBE) and the ratio of carbon to oxygen atoms in oxygenated compounds of dissolved organic matter (DOM). Data were acquired by a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS), equipped with a negative-mode electrospray ionization source. The slope and <I>y</I>-intercepts extracted from the linear relationship can be used to compare DOM samples originating from different locations. Significant differences in these parameters were observed between inland riverine and offshore coastal DOM samples. Offshore coastal DOM molecules underwent a change of one DBE for each removal or addition of two oxygen atoms. This suggested the existence of multiple carboxyl groups, each of which contains a double bond and two oxygen atoms. Inland riverine samples exhibited a change of ∼1.5 DBE following the addition or removal of two oxygen atoms. This extra change in DBE was attributed to cyclic structures or unsaturated chemical bonds. The DBE value with maximum relative abundance and the minimum DBE value for each class of oxygenated compounds showed that approximately two oxygen atoms contributed to a unity change in DBE. The qualitative analyses given here are in a good agreement with results obtained from analyses using orthogonal analytical techniques. This study demonstrates that DBE and the carbon number distribution, observed by high resolution mass spectrometry, can be valuable in elucidating and comparing structural features of oxygenated molecules of DOM.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2011/ancham.2011.83.issue-11/ac200464q/production/images/medium/ac-2011-00464q_0004.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ac200464q'>ACS Electronic Supporting Info</A></P>
고성환(SungHwan-Ko),채수용(SooYong-Chae),홍순찬(Soon-Chan Hong),고종선(JungSun-Ko),배창한(ChangHan-Bae),이병송(ByungSong-Lee),박현준 전력전자학회 2006 전력전자학술대회 논문집 Vol.- No.-
본 연구에서는 열차 추진 장치 시스템에 엔진의 중심부를 모의할 수 있는 Simplorer의 프로그램을 개발하여 M-G Set으로 모사한다. 열차의 엔진부와 발전기 구동에서의 제어는 DTC (Direct Torque Control) 제어로 모사 하였다. M-G Set을 구성은 견인력 토크지령을 받아 엔진부에서 DTC제어를 하였고, 발전기 구동 부는 속도지령을 받는 DTC제어로 하여 추진 장치 성능시험설비 열차운행모의에 의한 전력 조류 해석, 소비 및 회생전력을 분석할 수 있도록 하였다.
거리 정보를 이용한 되먹임 선형화 기법 무인기 편대 비행제어
김성환(Sunghwan Kim),유창경(Chang-Kyung Ryoo),박춘배(Choon-Bae Park) 제어로봇시스템학회 2009 제어·로봇·시스템학회 논문지 Vol.15 No.1
This paper addresses how to make a formation of multiple unmanned aerial vehicles (UAVs) using only the relative range information. Since the relative range can easily be measured by an on-board range sensor like the laser range finder, the proposed method does not require any expensive and heavy wireless communication system to share the navigation information of each vehicle. Based on the two-dimensional (2-D) nonlinear equations of motion, we propose a nonlinear formation controller using the typical input-output feedback linearization method. The performance of the proposed formation controller is verified by various numerical simulations.
소형 무인기들의 군집비행을 위한 운영 네트워크 시스템과 PILS 개발
김성환(Sunghwan Kim),조상욱(Sangook Cho),조성범(Seong-Beom Cho),박춘배(Choon-Bae Park) 제어로봇시스템학회 2012 제어·로봇·시스템학회 논문지 Vol.18 No.5
In this paper, a operation network system equipped with onboard wireless communication systems and ground-based mission control systems is proposed for swarm flight of small UAVs. This operating system can be divided into two networks, UaV communication network and ground control system. The UAV communication network is intend to exchange the informations of navigation, mission and flight status with minimum time delay. The ground control system consisted of mission control systems and UDP network. Proposed operation network system can make a swarm flight of various UAVs, execute complex missions decentralizing mission to several UAVs and cooperte several missions. Finally, PILS environments are developed based on the total operating system.