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RISS 인기검색어
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- 저자 : Sul Ki Hu (검색결과 4 건)
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A Modular Multilevel Converter with a Zigzag Transformer for Bipolar MVDC Distribution Systems
Cui, Shenghui,Lee, Joon-Hee,Hu, Jingxin,De Doncker, Rik W.,Sul, Seung-Ki Institute of Electrical and Electronics Engineers 2019 IEEE transactions on power electronics Vol.34 No.2
<P>This letter presents a modular multilevel converter (MMC) for bipolar medium-voltage direct-current (MVDC)) distribution systems. By employing a zigzag transformer as a grid interface transformer with a dedicated operation method, the operation of two dc poles of an MMC can be fully decoupled. Consequently, the MMC can provide full bipolar-operation capability. No additional component is required, and no penalty of increased power rating is imposed on the grid interface transformer. The scheme based on the proposed topology is competitive and cost-effective for emerging MVDC distribution systems. Feasibility of the proposed scheme is verified by both simulations and down-scale experiments.</P>
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Oral Bioavailability and Enterohepatic Recirculation of OtiloniumBromide in Rats
신범수,Jung Jun Kim,John Kim,Sul Ki Hu,Han Kyung Kim,Hye Suk Lee,Sun Dong Yoo 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.1
This study was conducted to examine the oral bioavailability and the possibility of enterohepatic recirculation of otilonium bromide in rats. A sensitive LC/MS/MS assay (LLOQ 0.5 ng/mL) was developed for the determination of otilonium and applied to i.v. and oral administration studies in bile duct cannulated (BDC) and non-BDC rats. After i.v. injection to BDC rats (1 mg/ kg as otilonium), average t1/2, CL, Vz and AUC were 7.9 ± 1.9 h, 8.7 ± 3.1 mL/min/kg, 5.7 ± 1.4 L/kg and 2,088 ± 676 ng·h/mL, respectively, and these values were comparable to those found in non-BDC rats. The percentages of i.v. dose excreted unchanged in bile and urine in BDC rats were 11.6 ± 3.0 and 3.1 ± 0.7%, respectively. Upon oral administration to non-BDC rats (20 mg/kg as otilonium), t1/2, Cmax, Tmax and AUC were 6.4 ± 1.3 h, 182.8 ± 44.6 ng/mL, 1.9 ± 1.6 h and 579 ± 113 ng·h/mL, respectively. The absolute oral bioavailability was low (1.1%), while the drug was preferentially distributed to gastrointestinal tissues. A secondary peak was observed in the serum concentration-time profiles in non-BDC rats following both i.v. and oral administration, indicating that otilonium bromide was subject to enterohepatic recirculation.
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Oral Bioavailability and Enterohepatic Recirculation of Otilonium Bromide in Rats
Shin, Beom-Soo,Kim, Jung-Jun,Kim, John,Hu, Sul-Ki,Kim, Hyoung-Jun,Hong, Seok-Hyun,Kim, Han-Kyung,Lee, Hye-Suk,Yoo, Sun-Dong 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.1
This study was conducted to examine the oral bioavailability and the possibility of enterohepatic recirculation of otilonium bromide in rats. A sensitive LC/MS/MS assay (LLOQ 0.5 ng/mL) was developed for the determination of otilonium and applied to i.v. and oral administration studies in bile duct cannulated (BDC) and non-BDC rats. After i.v. injection to BDC rats (1 mg/kg as otilonium), average $t_{1/2}$, CL, $V_z$ and AUC were $7.9\;{\pm}\;1.9\;h,\;8.7\;{\pm}\;3.1$ mL/min/kg, $5.7\;{\pm}\;1.4$ L/kg and $2,088\;{\pm}\;676\;ng{\cdot}h/mL$, respectively, and these values were comparable to those found in non-BDC rats. The percentages of i.v. dose excreted unchanged in bile and urine in BDC rats were $11.6\;{\pm}\;3.0$ and $3.1\;{\pm}\;0.7$%, respectively. Upon oral administration to non-BDC rats (20 mg/kg as otilonium), $t_{1/2},\;C_{max},\; T_{max}$ and AUC were $6.4\;{\pm}\;1.3\;h,\;182.8\;{\pm}\;44.6\;ng/mL,\; 1.9\;{\pm}\;1.6\;h$ and $579\;{\pm}\;113\;ng{\cdot}h/mL$, respectively. The absolute oral bioavailability was low (1.1%), while the drug was preferentially distributed to gastrointestinal tissues. A secondary peak was observed in the serum concentration-time profiles in non-BDC rats following both i.v. and oral administration, indicating that otilonium bromide was subject to enterohepatic recirculation.
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외부 열원 전도방식을 이용한 표면 이슬 맺힘 현상의 개선
김성진(Seong Jin Kim),강석훈(Seok Hoon Kang),박기홍(Ki Hong Park),유원설(Won Sul Yoo),박상후(Sang Hu Park),최호진(Ho Jin Choi) Korean Society for Precision Engineering 2011 한국정밀공학회지 Vol.28 No.6
Dew generation on an outer surface is considered as an important issue to be settled in the field of home appliances. In the case of a refrigerator that is subject to the dew generation problem on the surface of an outer-door of refrigeration thread, and so as to solve this problem, the electric heater is generally used for drying the dew. However, the heater inevitably requires electrical power consumption that is one of critical issues on the refrigerator. In this study, to prevent dew generation without the heater, a method of using induced heat from room temperature was proposed. In edge sides of a door, high conductive plates are installed and received the heat from outside that is relatively high temperature, and the heat is transferred onto dew generation region. Using prototypes, performance test was conducted under a certain temperature and humidity condition. The experimental results show that the surface temperature on the dew generation region was increased about 0.3~ 2.5℃ without use of any heater.
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