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        BMP-2 Immoblized in BCP-Chitosan-Hyaluronic Acid Hybrid Scaffold for Bone Tissue Engineering

        Nath, Subrata Deb,Abueva, Celine,Sarkar, Swapan Kumar,Lee, Byong Taek Materials Research Society of Korea 2014 한국재료학회지 Vol.24 No.12

        In this study, we fabricated a novel micro porous hybrid scaffold of biphasic calcium phosphate (BCP) and a polylectrolyte complex (PEC) of chitosan (CS) and hyaluronic acid (HA). The fabrication process included loading of CS-HA PEC in a bare BCP scaffold followed by lypophilization. SEM observation and porosimetry revealed that the scaffold was full of micro and macro pores with total porosity of more than 60 % and pore size in the range of $20{\sim}200{\mu}m$. The composite scaffold was mechanically stronger than the bare BCP scaffold and was significantly stronger than the CS-HA PEC polymer scaffold. Bone morphogenetic growth factor (BMP-2) was immobilized in CS-HA PEC in order to integrate the osteoinductive potentiality required for osteogenesis. The BCP frame, prepared by sponge replica, worked as a physical barrier that prolonged the BMP-2 release significantly. The preliminary biocompatibility data show improved biological performance of the BMP-2 immobilized hybrid scaffold in the presence of rabbit bone marrow stem cells (rBMSC).

      • KCI등재

        Detecting medicinal plants species using GPS positioning in Vidyasagar University Campus, Midnapore, West Bengal, India

        Sk. Md. Abu Imam Saadi,Ismail Mondal,Subrata Sarkar,Amal Kumar Mondal,Jatisankar Bandyopadhyay 대한공간정보학회 2017 Spatial Information Research Vol.25 No.1

        A portable global positioning system (GPS) unit was tested against conventional field techniques for our University Campus plot location the GPS accuracy tested against 3 benchmarks indicated that for the surrounding area the largest average displacement from true position was 48 m form the mean sea level. Five operators were instructed in the use of GPS for waypoint navigation ours University campus and seven plots were then located by each of the operators using either GPS or conventional field navigation. Results indicated that the operator with the least amount of plot-location experience was able to locate plots faster with GPS than by conventional techniques. System portability, satellite availability, canopy interference with signals, and operator biases are cited as moderate encumbrances. Our study documented the diversity of medicinal plants of Vidyasagar University campus and their adjoining area in the district of Paschim Medinipur, South West Bengal, India. This includes 117 species, 108 genera, distributed among 49 plant families under the division Marchantiophyta, Pteridophyta, Monocotyledones and Dicotyledones. Our field survey reportare represent 117 species among them some dominating family’s like- Poaceae (11), Fabaceae (10), Apocynaceae (7), Malvaceae (6), Asteraceae (5), Euphorbiaceae (5), Amarantheceae (4), Araceae (4), Acanthaceae (4). Among the 117 species, presented checklist includes herbs (62), shrubs (22), trees (22), climbers (10) and Branched thallus (1). We take step for conservation of all the plant species to protect from anthropogenic activities.

      • KCI등재

        Oral and maxillofacial injuries in children: a retrospective study

        Santanu Mukhopadhyay,Sauvik Galui,Raju Biswas,Subrata Saha,Subir Sarkar 대한구강악안면외과학회 2020 대한구강악안면외과학회지 Vol.46 No.3

        Objectives: The purpose of this retrospective epidemiological study was to determine the etiology and pattern of maxillofacial injuries in a pediatric population. Materials and Methods: Data for pediatric maxillofacial trauma patients aged 12 years and younger who were registered at the Department of Pediatric and Preventive Dentistry, Dr. R. Ahmed Dental College and Hospital, Kolkata, India, were reviewed and examined. Patients who were treated between October 2016 and September 2018 were analyzed according to age, sex, cause of injury, frequency and site of facial fractures, and soft tissue injuries. The chi-square tests were carried out for statistical analyses with a significance level of 5%. Results: Of 232 patients with a mean age of 6.77±3.25 years, there were 134 males (57.8%) and 98 females (42.2%). The overall male to female ratio was 1.39:1. The most common causes of injuries were falls (56.5%) and motor vehicle accidents (16.8%). Incidence of falls decreased significantly with age (P<0.001). Dentoalveolar injuries (61.6%) and soft tissue injuries (57.3%) were more common than facial fractures (42.7%). Mandibular fractures (82.8%) were the most common facial fractures, and perioral or lip injuries were the most prevalent injuries in our patient population. There was a positive association between facial fractures and soft tissue injury (P<0.01) (odds ratio 0.26; confidence interval 0.15-0.46). Conclusion: Falls were the leading cause of maxillofacial trauma in our sample of children, and the most common site of fractures was the mandible.

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