RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        Anti-tumor activities of Panax quinquefolius saponins and potential biomarkers in prostate cancer

        Shan He,Fangqiao Lyu,Lixia Lou,Lu Liu,Songlin Li,Johannes Jakowitsch,Yan Ma 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.2

        Background: Prostate carcinoma is the second most common cancer among men worldwide. Developing new therapeutic approaches and diagnostic biomarkers for prostate cancer (PC) is a significant need. The Chinese herbal medicine Panax quinquefolius saponins (PQS) have been reported to show anti-tumor effects. We hypothesized that PQS exhibits anti-cancer activity in human PC cells and we aimed to search for novel biomarkers allowing early diagnosis of PC. Methods: We used the human PC cell line DU145 and the prostate epithelial cell line PNT2 to perform cell viability assays, flow cytometric analysis of the cell cycle, and FACS-based apoptosis assays. Microarray-based gene expression analysis was used to display specific gene expression patterns and to search for novel biomarkers. Western blot and quantitative real-time PCR were performed to demonstrate the expression levels of multiple cancer-related genes. Results: Our data showed that PQS inhibited the viability of DU145 cells and induced cell cycle arrest at the G1 phase. A significant decrease in DU145 cell invasion and migration were observed after 24 h treatment by PQS. PQS up-regulated the expression levels of p21, p53, TMEM79, ACOXL, ETV5, and SPINT1 while it down-regulated the expression levels of bcl2, STAT3, FANCD2, DRD2, and TMPRSS2. Conclusion: PQS promoted cells apoptosis and inhibited the proliferation of DU145 cells, which suggests that PQS may be effective for treating PC. TMEM79 and ACOXL were expressed significantly higher in PNT2 than in DU145 cells and could be novel biomarker candidates for PC diagnosis.

      • SCIESCOPUSKCI등재

        Influence of Nocturnal Supplemental Lighting and Different Irrigation Regimes on Vase Life and Vase Performance of the Hybrid Rose ‘Charming Black’

        Liyun Shi,Songlin He,Zheng Wang,Wan Soon Kim 한국원예학회 2021 원예과학기술지 Vol.39 No.1

        Preharvest conditions, including photoperiod and irrigation regime, affect the keeping quality of long stem roses (Rosa x hybrida). Rose plants of the cultivar ‘Charming Black’ were subjected to four different treatments to investigate how nocturnal supplemental lighting and different irrigation regimes influence post-harvest performance. Vase life, ornamental quality, water balance, petal color, vacuolar pH, soluble sugar content, and soluble protein content were investigated in this study. Treatment with nocturnal supplemental lighting extended the vase life and increased the daily ornamental value in cut roses. In addition, flowers grown under nocturnal supplemental lighting and without irrigation had significantly improved flower color and ornamental value and the highest values for soluble sugar content and soluble protein content. Withholding irrigation under supplemental lighting promoted maintenance of the water balance, which prolonged the vase life of the cut flowers. This study illustrates that supplemental lighting is helpful in extending the vase life of cut roses and that a non-irrigation regime under supplemental lighting results in the most promising physiological and biochemical responses.

      • SCIESCOPUSKCI등재

        Effects of Root Pruning on Adventitious Root Formation, Enzyme Activities, and Hormone Levels in Paeonia suffruticosa ‘Fengdanbai’ Seedlings

        Zheng Wang,Gege Su,Songlin He,Liyun Shi,Dan He,Wenqian Shang,Dajuan Yang 한국원예학회 2021 원예과학기술지 Vol.39 No.1

        Root pruning during early root development can optimize the root structure of woody plants. To determine the effects of root pruning on tree peony (Paeonia suffruticosa), seedlings of the tree peony cultivar ‘Fengdanbai’ were subjected to varying degrees or different styles of root pruning. Various indexes were analyzed, including the anatomical structure of the root, root vitality, the activity levels of antioxidant enzymes, and the contents of endogenous hormones and their ratios. Comprehensive morphological observation showed that pruning freshly germinated roots that are 3 cm long by 1/3 (i.e., removing 1 cm) yielded the greatest rooting rate (90%), lateral root initiation (2.34 per seedling), and subsequent growth. Analysis of physiological and biochemical indicators during the critical rooting period (3-5 days after root pruning) showed that the levels of superoxide dismutase and abscisic acid (ABA) were decreased, while the oxidase activities of peroxidase, polyphenol oxidase, and indole acetate oxidase and the contents of the endogenous hormones indole acetic acid (IAA), gibberellin (GA3), and zeatin (ZT) were increased. IAA plays a key role in the process of adventitious root formation and the ratios of IAA/GA3, IAA/ABA, and IAA/ZT reflect endogenous hormone homeostasis during adventitious root formation. IAA/ABA and IAA/ZT showed higher values in the pruned roots compared to the control roots, which favor adventitious root induction and elongation. These results provide a basis for the study of adventitious root formation in tree peony.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼