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Masahide Ikeguchi,Keisuke Goto,June Watanabe,Shoichi Urushibara,Tomohiro Osaki,Kanenori Endo,Shigeru Tatebe,Seiichi Nakamura 한국간담췌외과학회 2019 Annals of hepato-biliary-pancreatic surgery Vol.23 No.4
Backgrounds/Aims: The prognostic nutritional index (PNI) is based on the albumin concentration and absolute lymphocyte count and is designed to assess the nutritional and immunological status of patients. In this study, we evaluated the prognostic importance of the preoperative and postoperative PNI in patients who underwent curative resection of pancreatic ductal adenocarcinoma (PDAC). Methods: From 2006 to 2017, 50 patients with PDAC underwent curative resection at our hospital. We performed distal pancreatectomy (DP) with splenectomy in 15 patients, pancreaticoduodenectomy (PD) in 27 patients, PD combined with portal vein partial resection in 6 patients, and total pancreatectomy with splenectomy in 2 patients. We compared the preoperative PNI and postoperative PNI (1 and 2 months postoperatively) and analyzed the prognostic importance for these patients. Results: The mean PNI significantly decreased from 45.5 preoperatively to 39.8 at 1 month postoperatively (p<0.001), but recovered to 42.7 at 2 months postoperatively. In 23 patients, the PNI at 2 months postoperatively recovered to the preoperative level (recovered group), but in the remaining 27 patients, the PNI at 2 months postoperatively did not reach the preoperative level (non-recovered group). The overall median survival time in the recovered group (29 months) was significantly longer than that in the non-recovered group (12 months, p=0.003). The multivariate overall analysis demonstrated that good recovery of the postoperative PNI was strongly correlated with a better prognosis. Conclusions: Effective postoperative nutrition may have a prognostic benefit for patients with operable PDAC.
The phase transitions of hydrogen bonded ferroelectric CsH2PO4 under high pressure
Yuki Nakamoto,Kiyoshi Deguchi,Kouichi Tashima,Li Chung Ming,Shinji Azuma,Shoichi Endo,Takumi Kikegawa 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.46 No.1
Dielectric-constant measurements of a hydrogen-bonded crystal CsH2PO4 were carried out at low temperature (4 K < T < 300 K) under high pressure up to 3.0 GPa. By the dielectric measurements, we discovered two new high-pressure phases at about 1.3 GPa and 2.55 GPa, which are named as phases V and VI, respectively. These phases have a stable pressure region higher than that of the previously reported phase AFEII. On the other hand, at ambient temperature two phase transitions were previously found at 2.9 and 4.1 GPa through X-ray diraction study. However, we could not observe any anomaly corresponding to these phase transitions in the present dielectric measurement.