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      • KCI등재

        Honey in Bronchial Asthma: From Folk Tales to Scientific Facts

        Alzhraa Salah Abbas,Sherief Ghozy,Le Huu Nhat Minh,Mohammad Rashidul Hashan,Ali Lotfy Soliman,Nguyen Thanh Van,Kenji Hirayama,Nguyen Tien Huy 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.6

        Bronchial asthma is one of the most common chronic inflammatory diseases. Complementary and alternative medicine is increasingly used for treating bronchial asthma. Ten electronic databases were searched to investigate whether honey alone or in combination with other ingredients can be considered as the potential treatment for bronchial asthma. Combinations of honey and Nigella sativa (NS) showed significant improvement in all pulmonary functions, including forced expiratory volume (FEV1) (MD = 0.52, P < .001), forced vital capacity (FVC) (MD = 0.55, P = .002), and peak expiratory flow rate (PEFR) (MD = 80.60, P < .001), in both moderate and severe, uncontrolled persistent asthma compared with baseline. Asthma control test scores also improved significantly (MD = 11.22, P < .001) in patients using combinations of honey and NS compared with baseline. Patients with a less severe grade of asthma showed a significant positive response in clinical parameters upon using honey. One study showed that using celery seeds and honey was associated with clinical improvement of both lung functions, FEV1 (MD = 18.09, P < .001) and FVC (MD = 24.23, P < .001), and respiratory parameters compared with baseline. In conclusion, honey alone has no strong evidence of being effective in controlling asthma. However, when used in combination with other substances, it showed a relatively high efficacy in patients with asthma. This finding may help in asthma control with lower cost alternatives and better outcomes.

      • KCI등재

        Management of Adult Unruptured Brain Arteriovenous Malformations: An Updated Network Meta-Analysis

        Dmytriw Adam A.,Ku Jerry,Ghozy Sherief,Grewal Sahibjot,Cancelliere Nicole M.,Azzam Ahmed Y.,Robert W. Regenhardt,Rabinov James D.,Christopher J. Stapleton,Patel Krunal,Patel Aman B.,Pereira Vitor Mend 대한신경중재치료의학회 2023 Neurointervention Vol.18 No.2

        The management of unruptured brain arteriovenous malformations (ubAVMs) is a complex challenge to neurovascular practitioners. This meta-analysis aimed to identify the optimal management of ubAVMs comparing conservative management, embolization, radiosurgery, microsurgical resection, and multimodality. The search strategy was developed a priori according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched the Ovid Medline, Embase, Web of Science, and Cochrane Library databases to identify relevant papers. Using R version 4.1.1., a frequentist network meta-analysis was conducted to compare different management modalities for the ubAVMs. Overall, the conservative group had the lowest risk of rupture (P-score=0.77), and the lowest rate of complications was found in the conservative group (P-score=1). Among different interventions, the multimodality group had the highest rupture risk (P-score=0.34), the lowest overall complications (P-score=0.75), the best functional improvement (P-score=0.65), and the lowest overall mortality (P-score=0.8). However, multimodality treatment showed a significantly higher risk of rupture (odds ratio [OR]=2.13; 95% confidence interval [95% CI]=1.18–3.86) and overall complication rate (OR=5.56; 95% CI=3.37–9.15) compared to conservative management; nevertheless, there were no significant differences in overall mortality or functional independence when considered independently. Conservative management is associated with the lowest rupture risk and complication rate overall. A multimodal approach is the best option when considering mortality rates and functional improvement in the context of existing morbidity/symptoms. Microsurgery, embolization, and radiosurgery alone are similar to the natural history in terms of functional improvement and mortality, but have higher complication rates.

      • SCOPUSKCI등재

        A closer look at the high burden of psychiatric disorders among healthcare workers in Egypt during the COVID-19 pandemic

        Amr Ehab El-Qushayri,Abdullah Dahy,Abdullah Reda,Mariam Abdelmageed Mahmoud,Sarah Abdel Mageed,Ahmed Mostafa Ahmed Kamel,Sherief Ghozy 한국역학회 2021 Epidemiology and Health Vol.43 No.-

        OBJECTIVES: This study aimed to examine the prevalence of psychiatric disorders among Egyptian healthcare workers (HCWs) during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: Six databases were searched for relevant papers. The quality of the selected articles was measured using the Na-tional Institute of Health quality assessment tool. We used a fixed-effects model when there was no heterogeneity and a ran-dom-effects model when there was heterogeneity. RESULTS: After screening 197 records, 10 studies were ultimately included. Anxiety was the most commonly reported psychi-atric disorder among HCWs, with a prevalence of 71.8% (95% confidence interval [CI], 49.4 to 86.9), followed by stress (66.6%; 95% CI, 47.6 to 81.3), depression (65.5%; 95% CI, 46.9 to 80.3), and insomnia (57.9%; 95% CI, 45.9 to 69.0). As measured using the 21-item Depression, Anxiety, and Stress Scale, the most common level of severity was moderate for depression (22.5%; 95% CI, 19.8 to 25.5) and stress (14.5%; 95% CI, 8.8 to 22.9), while high-severity anxiety was more common than other levels of se-verity (28.2%; 95% CI, 3.8 to 79.6). CONCLUSIONS: The COVID-19 pandemic has had a negative effect on Egyptian HCWs’ psychological well-being. More psychological support and preventive measures should be implemented to prevent the further development of psychiatric ill-ness among physicians and other HCWs.

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