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Alok Sharma,G.D. Reddy,Atul Kaushik,K.Shanker,R.K. Tiwari,Alok Mukherjee,Ch.V. Rao 한국생약학회 2007 Natural Product Sciences Vol.13 No.1
ethanolic (50% v/v) extracts of Carissa carandas (fruits) (Apocynaceae) and Microstylis wallichii(tubers) (Orchidaceae) were examined for anti-inflamatory and analgesic activities in experimental animals.Carissa carandas and Microstylis wallichii (50 - 200 mg/kg) caused a dose dependent inhibition of swellingcaused by carrageenin significantly in cotton pellet induced granuloma in rats (P < 0.05 to P < 0.001). There was asignificant increase in the analgesy meter induced pain in rats. The extracts of Carissa carandas and Microstyliswallichii resulted in an inhibition of stretching episodes and percentage protection was 16.05 - 17.58%respectively in acetic acid induced writhing.KeywordsCarissa carandas, Microstylis wallichii, pain, inflamation