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      • KCI등재후보

        Effects of targeted remediation in anatomy for first year medical students

        Nachiket Shankar,Nachiket Shankar,Yogitha Ravindranath,Roopa Ravindranath,Henal Shah 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.1

        The aim of this study was to assess the effectiveness of a questionnaire to guide targeted remediation among undergraduate medical students in anatomy. Seventy-five students from a medical college in South India who failed in the first internal theory examination were administered a validated 35-item questionnaire. The total and domain specific questionnaire scores were calculated. Specific weekly interventions for each student based on the questionnaire scores were conducted by appointed academic mentors for three months prior to the second internal examination. The dependent variable was performance in the second internal examination. The students were re-administered the questionnaire after the second internal examination. The independent variables were the marks obtained in the first internal examination, domain specific and total questionnaire scores, sex, and regularity of the student in attending the remedial sessions. Inferential statistical tests used were the chi-square test, independent sample t test, paired t test, multiple regression and binomial logistic regression. Of the 75 students who underwent remediation, 54 (72%) passed in the second internal examination. The scores in the second internal examination among these students was found to be significantly higher as compared to the first internal examination. The total, subject related and study skills questionnaire score were significantly lower after remediation. Students who were irregular had a significantly lower pass rate. The multivariate analysis showed that only the first internal marks added significantly to the prediction about second internal performance. This study provides evidence to show that struggling students perceive a benefit from targeted remediation.

      • Level of Awareness of Cervical and Breast Cancer Risk Factors and Safe Practices among College Teachers of Different States in India: Do Awareness Programmes Have an Impact on Adoption of Safe Practices?

        Shankar, Abhishek,Rath, G.K.,Roy, Shubham,Malik, Abhidha,Bhandari, Ruchir,Kishor, Kunal,Barnwal, Keshav,Upadyaya, Sneha,Srivastava, Vivek,Singh, Rajan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

        Background: Breast and cervical cancers are the most common causes of cancer mortality among women in India, but actually they are largely preventable diseases. Although early detection is the only way to reduce morbidity and mortality, there are limited data on breast and cervical cancer knowledge, safe practices and attitudes of teachers in India. The purpose of this study is to assess the level of awareness and impact of awareness programs in adoption of safe practices in prevention and early detection. Materials and Methods: This assessment was part of a pink chain campaign on cancer awareness. During cancer awareness events in 2011 at various women colleges in different parts in India, a pre-test related to cervical cancer and breast cancer was followed by an awareness program. Post-tests using the same questionnaire were conducted at the end of the interactive session, at 6 months and 1 year. Results: A total of 156 out of 182 teachers participated in the study (overall response rate was 85.7 %). Mean age of the study population was 42.4 years (range- 28-59 yrs). There was a significant increase in level of knowledge regarding cervical and breast cancer at 6 months and this was sustained at 1 year. Adoption of breast self examination (BSE) was significantly more frequent in comparison to CBE, mammography and the Pap test. Magazines and newspapers were sources for knowledge regarding screening tests for breast cancer in more than 60% of teachers where as more than 75% were educated by doctors regarding the Pap test. Post awareness at 6 months and 1 year, there was a significant change in alcohol and smoking habits. Major reasons for not doing screening test were found to be ignorance (50%), lethargic attitude (44.8%) and lack of time (34.6%). Conclusions: Level of knowledge of breast cancer risk factors, symptoms and screening methods was high as compared to cervical cancer. There was a significant increase in level of knowledge regarding cervical and breast cancer at 6 months and this was sustained at 1 year. Adoption of BSE was significantly greater in comparison to CBE, mammography and the Pap test. To inculcate safe practices in lifestyle of people, awareness programmes such as pink chain campaign should be conducted more widely and frequently.

      • Alginate-based nanocomposite films reinforced with halloysite nanotubes functionalized by alkali treatment and zinc oxide nanoparticles

        Shankar, Shiv,Kasapis, Stefan,Rhim, Jong-Whan Elsevier 2018 International journal of biological macromolecules Vol.118 No.2

        <P><B>Abstract</B></P> <P>Functionalized halloysite nanotubes were prepared by surface activation of halloysite (Hal) with sodium hydroxide and deposition of zinc oxide nanoparticles (ZnONP). The surface charge of Hal was changed from 0.18 ± 0.6 mV to −35.2 ± 2.8 mV after alkali treatment. The functionalized Hal (AT-Hal/ZnONP) was incorporated into alginate biopolymer as a reinforcing filler with different concentration of AT-Hal/ZnONP (1, 3, 5, and 7 wt% of alginate). Alginate films with AT-Hal/ZnONP exhibited a significant increase in the mechanical, water vapor barrier, and UV light barrier properties. The thermal stability of composite films has not changed after AT-Hal/ZnONP incorporation. The AT-Hal/ZnONP incorporated alginate films demonstrated strong antibacterial activity against food-borne pathogenic bacteria, <I>Escherichia coli</I> and <I>Listeria monocytogenes</I>. The nanocomposite film with 7 wt% of AT-Hal/ZnONP exhibited complete sterilization of <I>E. coli</I> and <I>L. monocytogenes</I> after 3 and 9 h of treatment, respectively.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Halloysite (Hal) was activated with sodium hydroxide. </LI> <LI> Zinc oxide nanoparticles (ZnONP) were deposited on the alkali treated halloysite (AT-Hal). </LI> <LI> At-Hal/ZnONP was incorporated to form alginate-based nanocomposite films. </LI> <LI> The nanocomposite films increased mechanical, water vapor barrier, and UV light barrier properties. </LI> <LI> The nanocomposite films exhibited strong antibacterial activity. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Change in Trend in Various Clinico-Pathological Factors and Treatment Profile of Breast Cancer Patients: a Tertiary Cancer Centre Experience

        Shankar, Abhishek,Roy, Shubham,Rath, GK,Kamal, Vineet Kumar,Bhandari, Menal,Kulshrestha, Rashi,Prasad, Neelam,Sachdev, Jaineet,Jeyaraj, Pamela Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.8

        Background: Breast cancer is by far the most frequent cancer of women (23% of all cancers), ranking second overall when both sexes are considered together. Since there has been change in clinico-pathological factors and treatment profiles for breast cancer patients over the years, the present study to evaluate the change trends in India. Materials and Methods: A detailed analysis was carried out with respect to age, menopausal status, family history, disease stage, surgery performed, histopathology, hormone receptor status, and use of chemotherapy or hormonal therapy. Change in various clinico-pathological factors and treatments of breast cancer cases was recorded and analysed. Results: Mean age at presentation was found to be earlier in 2005-2006 compared with 1997-98 (p value: 0.046). More premenopausal women were diagnosed with breast cancer in 2005-2006 when this was compared with initial years of assessment (p value ${\leq}0.001$). When change in the receptor status was evaluated, we observed that there was a decrease in cases of ER and PR receptor positivity which was significant (p value: 0.007). Over the period of time, more f patients were not offered surgery initially in view of advanced disease when the two time periods were compared (p value: ${\leq}0.001$). There was a significant increase in patients who were initially offered neo-adjuvant chemotherapy in view of advanced disease at presentation (p value: ${\leq}0.001$). There was increasing number of patients who received palliative treatment for symptoms in 2005-2006 when compared to patients treated in 1997-98((p value: ${\leq}0.001$). Conclusions: Changes in mean age at presentation, premenopausal status, and stage at presentation have occurred over the years. More aggressive patterns of disease have become more common with early age at presentation and aggressive biological behaviour with receptor negative tumours.

      • KCI등재

        Properties of ZnO:Al Films Prepared by Spin Coating of Aged Precursor Solution

        Shankar Prasad Shrestha,Jeevan Jyoti Nakarmi,Young-Sung Kim,Rishi Ghimire,Sabita Shrestha,박종윤,Jin-Hyo Boo 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.1

        Transparent conducting undoped and Al impurity doped ZnO films were deposited on glass substrate by spin coat technique using 24 days aged ZnO precursor solution with solution of ethanol and diethanolamine. The films were characterized by UV-Visible spectroscopy, X-ray diffraction (XRD), scanning electron microscope (SEM), electrical resistivity (ρ), carrier concentration (n), and hall mobility (μ) measurements. XRD data show that the deposited film shows polycrystalline nature with hexagonal wurtzite structure with preferential orientation along (002) crystal plane. The SEM images show that surface morphology, porosity and grain sizes are affected by doping concentration. The Aldoped samples show high transmittance and better resistivity. With increasing Al concentration only mild change inoptical band gap is observed. Optical properties are not affected by aging of parent solution. A lowest resistivity (8.5 ×10-2 ohm cm) is observed at 2 atomic percent (at.%) Al. With further increase in Al concentration, the resistivity started to increase significantly. The decrease resistivity with increasing Al concentration can be attributed to increase in both carrier concentration and hall mobility.

      • KCI등재

        Investigation of friction in rectangular Nitrile-Butadiene Rubber (NBR) hydraulic rod seals for defence applications

        Shankar Bhaumik,A. Kumaraswamy,S. Guruprasad,P. Bhandari 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.11

        Contact based FE simulations have been carried out to estimate the contact pressure distribution at seal/rod interface at sealed oil pressuresof 10, 20 and 30 MPa and constant rod velocity of 0.12 m/s. Oil film thickness at the interface was then computed analytically atvarious combinations of oil pressures and rod velocities. Seal contact pressure and oil film thickness data along with surface roughness,intermolecular interaction between seal/rod interfaces has been perused to estimate the friction in Nitrile-Butadiene Rubber (NBR) rectangularhydraulic rod seals using theoretical models such as Inverse hydrodynamic lubrication (IHL), Greenwood-Williamson (GW)and Wassink’s models. The friction at seal/rod interface was also measured experimentally using a specially designed test rig. The comparisonof theoretical and experimental data revealed that, friction computed from GW and Wassink’s models had good agreement withthe experimental results.

      • KCI등재

        Effects of Concentration of ZnO Nanoparticles on Mechanical, Optical, Thermal, and Antimicrobial Properties of Gelatin/ZnO Nanocomposite Films

        Shankar, Shiv,Teng, Xinnan,Rhim, Jong-Whan Korea Society of Packaging Science and Technology 2014 한국포장학회지 Vol.20 No.2

        This study illustrates the synthesis of gelatin based zinc oxide nanoparticle (ZnONPs) incorporated nanocomposite films using different concentrations of ZnONPs. The ZnONPs were oval in shape and the size ranged from 100- 200 nm. The nanocomposite films were characterized by UV-visible, FE-SEM, FT-IR, and XRD. The concentrations of ZnONPs greatly influenced the properties of nanocomposite films. The absorption peaks around 360 nm increased with the increasing concentrations of ZnONPs. The surface color of film did not change while transmittance at 280 nm was greatly reduced with increase in the concentration of ZnONPs. FTIR spectra showed the interaction of ZnONPs with gelatin. XRD data demonstrated the crystalline nature of ZnONPs. The thermostability, char content, water contact angle, water vapor permeability, moisture content, and elongation at break of nanocomposite films increased, whereas, tensile strength and modulus decreased with increase in the concentrations of ZnONPs. The gelatin/ZnONPs nanocomposite films showed profound antibacterial activity against both Gram-positive and Gram-negative food-borne pathogenic bacteria. The gelatin/$ZnONP^{1.5}$ nanocomposite film showed the best UV barrier and antimicrobial properties among the tested-films, which indicated a high potential for use as an active food packaging films with environmentally-friendly nature.

      • SCISCIESCOPUS

        Antimicrobial wrapping paper coated with a ternary blend of carbohydrates (alginate, carboxymethyl cellulose, carrageenan) and grapefruit seed extract

        Shankar, Shiv,Rhim, Jong-Whan Elsevier 2018 Carbohydrate Polymers Vol.196 No.-

        <P><B>Abstract</B></P> <P>A functional biopolymer-coated paper was prepared by coating a ternary blend of the alginate, carboxymethyl cellulose, and carrageenan with grapefruit seed extract (GSE) for the substitute use of synthetic polymer-coated paper. The microstructure of the surface and cross-section of the coated paper analyzed by field emission scanning electron microscope (FE-SEM) indicated that the biopolymer was compatible with the base paper and filled the pores of the porous fiber to make a smooth-surfaced coating paper. The properties of the biopolymer-coated paper, such as water and oil resistance, water vapor barrier, surface hydrophobicity, and mechanical properties, increased significantly compared with not only the base paper but also commercially used PE-coated paper. The blended biopolymer coating material exhibited strong antibacterial activity against food-borne pathogenic bacteria, <I>Listeria monocytogenes</I> and <I>Escherichia coli</I>, which were destroyed completely within 3 and 9 h, respectively. The packaging test for a minced fish cake packed with the biopolymer-coated paper showed the complete destruction of surface inoculated bacteria in 6–9 days. The biopolymer-coated paper showed a high potential for disposable food packaging applications to increase the shelf-life of packaged food.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A ternary blend of the alginate, carboxymethyl cellulose, and carrageenan with grapefruit seed extract (GSE) was used for coating of paper. </LI> <LI> Water and oil resistance properties of paper increased after coating. </LI> <LI> Water vapor barrier, surface hydrophobicity, and mechanical properties, increased significantly after coating. </LI> <LI> Blended biopolymer coating material exhibited strong antibacterial activity. </LI> <LI> The biopolymer-coated paper showed a high potential for disposable food packaging applications. </LI> </UL> </P>

      • Revisiting the Bulge-Halo Conspiracy. I. Dependence on Galaxy Properties and Halo Mass

        Shankar, Francesco,Sonnenfeld, Alessandro,Mamon, Gary A.,Chae, Kyu-Hyun,Gavazzi, Raphael,Treu, Tommaso,Diemer, Benedikt,Nipoti, Carlo,Buchan, Stewart,Bernardi, Mariangela,Sheth, Ravi,Huertas-Company, American Astronomical Society 2017 The Astrophysical Journal Vol.840 No.1

        <P>We carry out a systematic investigation of the total mass density profile of massive (log M-star / M-circle dot greater than or similar to 11.3) early-type galaxies and its dependence on galactic properties and host halo mass with the aid of a variety of lensing/dynamical data and large mock galaxy catalogs. The latter are produced via semi-empirical models that, by design, are based on just a few basic input assumptions. Galaxies. with measured stellar masses, effective radii, and Sersic indices, are assigned, via abundance matching relations, host dark matter halos characterized by a typical Lambda CDM profile. Our main results are as follows. (1) In line with observational evidence, our semi-empirical models naturally predict that the total, mass-weighted density slope at the effective radius gamma' is not universal, steepening for more compact and/or massive galaxies, but flattening with increasing host halo mass. (2) Models characterized by a Salpeter or variable initial mass function (IMF) and uncontracted dark matter profiles are in good agreement with the data, while a Chabrier IMF and/or adiabatic contractions/expansions of the dark matter halos are highly disfavored. (3) Currently available data on the mass density profiles of very massive galaxies (log M-star / M-circle dot greater than or similar to 12), with M-halo greater than or similar to 3 x 10(14) M-circle dot, favor instead models with a stellar profile flatter than a Sersic one in the very inner regions (r less than or similar to 3-5 kpc), and a cored NFW or Einasto dark matter profile with median halo concentration a factor of similar to 2 or less than or similar to 1.3, respectively, higher than those typically predicted by N-body numerical simulations.</P>

      • Facile approach for large-scale production of metal and metal oxide nanoparticles and preparation of antibacterial cotton pads

        Shankar, Shiv,Rhim, Jong-Whan Elsevier 2017 Carbohydrate polymers Vol.163 No.-

        <P><B>Abstract</B></P> <P>Metallic nanoparticles such as zinc oxide (ZnONPs), copper oxide (CuONPs), and silver (AgNPs) were synthesized in gram scale using green methods. The antibacterial cotton fibers/nanoparticles (cotton fibers/NPs) composite pads were prepared, and nanoparticle binding/release tests were performed. All the NPs were crystalline and showed characteristic XRD diffraction peaks and showed the characteristic FTIR bands of the respective nanoparticles. All the NPs showed strong antimicrobial activity against Gram-positive and Gram-negative pathogenic bacteria. The NPs were attached to the cotton pad by adsorption at different extent depending on the types of nanoparticles. The adsorption and release of nanoparticles on and from cotton pads were also dependent on the types of nanoparticles. The NPs-adsorbed cotton pads showed potent antibacterial activity against pathogenic bacteria such as <I>Escherichia coli, Listeria monocytogenes, Staphylococcus aureus,</I> and <I>Staphylococcus epidermis.</I> The developed NPs-adsorbed cotton pads have potential to be used as wound dressings and antibacterial food packaging applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Metallic nanoparticles (ZnONPs, CuONPs, and AgNPs) were synthesized in gram scale. </LI> <LI> NPs-adsorbed antimicrobial cotton pads were prepared. </LI> <LI> Binding and releasing of NPs from the cotton pad were dependent on the type of NPs. </LI> <LI> The NPs-adsorbed cotton pads exhibited strong antibacterial activity. </LI> <LI> It has a potential for the wound dressing and food packaging applications. </LI> </UL> </P>

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