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      • KCI등재

        Theoretical investigation of electronic structure and optical response in relation to the transport properties of Ga1-xInxN (x = 0, 0.25, 0.50, 0.75)

        Fahad Ali Shah,Saleem Ayaz Khan,Suneela Arif,Sikander Azam,R. Khenata,S. Bin Omran 한국물리학회 2015 Current Applied Physics Vol.15 No.5

        The state-of-the-art all-electron FLPAW method and the BoltzTrap software package based on semiclassical theory were adopted to explore the electronic structure and the optical and thermoelectric properties of Ga1-xInxN. Ga1-xInxN is predicted to be a direct band gap material for all values of x. Moreover, the band gap varies between 2.99 eV and 1.95 eV as x changes. Optical parameters such as the dielectric constant, absorption coefficient, reflectivity and refractive index are calculated and discussed in detail. The doping of In plays an important role in the modulation of the optical constants. The static dielectric constant ε (0) of Ga1-xInxN was calculated as 3.95, 3.99, 3.99 and 4.03 at x = 0.00, 0.25, 0.50 and 0.75, respectively. The static refractive index is 2.0 for pure Ga1-xInxN at x = 0.00. The thermal properties varied greatly as x fluctuated. The ternary alloy has large values for the Seebeck coefficient and figure of merit at high temperatures and is thus suitable for thermoelectric applications. Pure Ga1-xInxN at x = 0 exhibited ZT = 0.80 at room temperature, and at higher temperatures, the thermal conductivity decreased with increased In doping.

      • KCI등재

        Therapeutic role of medicinal plant extracts and bioactive compounds in osteoarthritis

        Fahad Hassan Shah,김송자 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.4

        Osteoarthritis (OA) is a musculoskeletal disorder characterized by degeneration of articular cartilages facilitated by inflammation, cartilage and extracellular matrix degrading enzymes and chondrocyte dedifferentiation and depletion. The current therapy for OA failed to avert the degeneration of articular cartilage due to elusive molecular nature, multifarious signaling pathway and molecular targets implicated in this disease. These reasons are imposing hefty economic burden globally which necessitate for the discovery and development of multi-action drugs capable of stunting diseased condition. Medicinal plants accommodate various bioactive compounds that have a role in regulating inflammation and tissue regenerative properties. These compounds and plant extracts interact with multiple drug targets and disease pathways which make them attractive candidate for OA therapy. Recently, numerous compounds have been explored in OA induced animal and cell line models that significantly improved the cartilage integrity, extracellular matrix production and chondrocyte survival. In this review, we reviewed medicinal plant extracts and bioactive components and their therapeutic influence in OA therapy.

      • Grey wolf optimization based clustering algorithm for vehicular ad-hoc networks

        Fahad, Muhammad,Aadil, Farhan,Rehman, Zahoor-ur-,Khan, Salabat,Shah, Peer Azmat,Muhammad, Khan,Lloret, Jaime,Wang, Haoxiang,Lee, Jong Weon,Mehmood, Irfan Elsevier 2018 Computers & electrical engineering Vol.70 No.-

        <P>In vehicular ad-hoc network (VANETs), frequent topology changes occur due to fast moving nature of mobile nodes. This random topology creates instability that leads to scalability issues. To overcome this problem, clustering can be performed. Existing approaches for clustering in VANETs generate large number of cluster-heads which utilize the scarce wireless resources resulting in degraded performance. In this article, grey wolf optimization based clustering algorithm for VANETs is proposed, that replicates the social behaviour and hunting mechanism of grey wolfs for creating efficient clusters. The linearly decreasing factor of grey wolf nature enforces to converge earlier, which provides the optimized number of clusters. The proposed method is compared with well-known meta-heuristics from literature and results show that it provides optimal outcomes that lead to a robust routing protocol for clustering of VANETs, which is appropriate for highways and can accomplish quality communication, confirming reliable delivery of information to each vehicle. (C) 2018 Elsevier Ltd. All rights reserved.</P>

      • KCI등재

        Cross-Linked Poly(cyclotriphosphazene-co-phloretin) Microspheres and Their Application for Controlled Drug Delivery

        Sahid Mehmood,Haojie Yu,Li Wang,Md Alim Uddin,Bilal Ul Amin,Fazal Haq,Shah Fahad,Muhammad Haroon 한국고분자학회 2022 Macromolecular Research Vol.30 No.9

        In this work, cross-linked poly(cyclotriphosphazene-co-phloretin) (PCTPPT) microspheres were synthesized and characterized by Fourier transform infrared (FT-IR) spectroscopy and scanning electron microscope (SEM). In FT-IR spectra, the new appeared bands at 1009 cm-1 and 1132 cm-1 confirmed the successful polymerization between hexachlorocyclotriphosphazene (HCCP) and phloretin (Pht). While the SEM results showed that the size of the microspheres was strongly dependent on the HCCP:Pht mole ratio. The crystalline nature of the PCTPPT microspheres was checked by X-ray diffraction (XRD) and provided evidence for the successful preparation of the microspheres. The thermal stability of the PCTPPT microspheres was investigated by thermogravimetric analysis (TGA). The obtained TGA results showed that the increase in thermal stability was attributed to the highly cross-linked covalently bonded structure of PCTPPT microspheres. The particle size distribution was determined by dynamic light scattering (DLS) and the results showed that the decreased HCCP:Pht mole ratio increases the size of the microspheres. The PCTPPT-3 microspheres were used as drug carriers for a model drug camptothecin (CPT). The experimental findings showed a cumulative release of 41.0% in pH 4.0 and 32.6% in pH 7.4 after 350 h and the PCTPPT-3/CPT microspheres have good drug loading capability and controlled release property for CPT.

      • SCOPUSKCI등재

        Synthesis of carboxymethyl starch grafted polyvinyl imidazole (CMS-g-PVIs) and their role as an absorbent for the removal of phenol

        Fazal Haq,Haojie Yu,Li Wang,Lisong Teng,Sahid Mehmood,Muhammad Haroon,Bilal-Ul-Amin,Shah Fahad,Md Alim Uddin,Di Shen 대한환경공학회 2021 Environmental Engineering Research Vol.26 No.5

        Cigarette industry plays an important role in the economy of the advanced countries. But the cigarette smoke contains toxic chemicals such as phenol which causes various kind of diseases and affect human life. In this paper, we synthesized carboxymethyl starch grafted poly vinyl imidazole (CMS-g-PVIs) by reacting carboxymehtyl starch (CMS) with vinyl imidazole (VI). The structures of the CMS-g-PVIs were investigated by 1H NMR and FT-IR. The crystalline properties of the CMS and CMS-g-PVIs were checked by XRD. The thermal properties of the original CMS and CMS-g-PVIs were investigated by TGA analysis. It was found that the modified starches had high thermal stability due to aromatic imidazole ring. The modified starches also showed more rough and distorted morphology as compared to native CMS. The CMS-g-PVIs were subjected for phenol adsorption and showed adsorption efficiencies of 0.170 g/g, 0.190 g/g, 0.192 g/g and 0.199 g/g for CMS, CMS-g-PVI 1, CMS-g-PVI 2 and CMS-g-PVI 3, respectively. Due to higher grafting ratio, CMS-g-PVI 3 showed good adsorption efficiency of 0.199 g/g for phenol. The obtained results showed that the grafting of vinyl imidazole on CMS can increase the adsorption efficiency of native CMS towards phenol.

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