Dental Hetero-Graft Materials with Nano Hydroxyapatite Surface Treatment

Kim, Dai-Hwan,Kim, Kyung-Il,Yoon, Seokyoung,Kim, Hyung-Jo,Ahn, Jin-Soo,Jun, Sang Ho,Kang, Ho Chang,Pang, Changhyun,Kim, Jaeyun,Cha, Hyung Joon American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.10

<P>We report the development of hydroxyapatite nanoparticle (HAp NP)-functionalized hetero-graft materials (HGMs) for dental applications. These HGMs were prepared by attaching platelet-, needle-, and sphere-shaped HAp NPs to the surface of xenograft materials through chemical conjugation. Although all three HAp NPs contributed to increase the surface area of bone graft material (BGM), the shape of the HAp NPs was a determining factor. Platelet HAp NPs were most effective, because they caused a 48.9% increase in BGM surface area whereas the influence of the spherical NP was only a 6.7% increase. This suggests that geometric factors regarding both the attached HAp NPs and graft material surface are essential in controlling the surface roughness of graft materials. Among the three HAp NPs, it was the platelet HAp NPs that helped to increase the efficacy of the BGM most significantly. Compared with BGM with no HAp NP attachment, HGM with platelet HAp NP ('platelet-HGM) treatment had similar to 46.1% higher cell attachment and proliferation rate. The MU assay also showed that the HAp NP-treated hetero-graft materials had negligible cytotoxicity.</P>

Neurogenic rosacea in Korea

( Hyeone Kim ),( Seokyoung Kang ),( Koeun Kim ),( Soyun Cho ),( Kwangho Kim ),( Il-hwan Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Rosacea with severe neurologic symptoms such as burning and stinging is often not effectively treated with conventional therapies. Objectives: The aim of this study was to investigate the clinical characteristics of Korean rosacea patients with prominent neurological symptoms. Methods: In the present study, the demographic features, medical history, clinical manifestations, and treatment modalities of 17 neurogenic rosacea patients that had prominent neurologic symptoms and 106 erythematotelangiectatic rosacea (ETR) patients are investigated as a control group. Results: All seventeen neurogenic rosacea patients had severe persistent erythema with burning/stinging sensation limited to both cheeks. Among these patients, 94.1% were female (16/17), 23.6 % had dyslipidemia (4/17), 17.7 % had hypertension (3/17), and 17.7% had psychiatric diseases. Heat stimuli (58.8 %, [10/17]), and stress (52.9 %, [9/17]) were major aggravating factors. Cold stimuli alleviated the symptoms in half of the patients (41.2 %, [7/17]). Fourteen of seventeen patients (82.3 %) improved after receiving anticonvulsants and antidepressants. Conclusion: Rosacea patients with severe neurologic symptoms show distinct clinical manifestations and should be classified separately, and a different therapeutic approach is necessary for them

LiDAR 누적 기반 고밀도 점군데이터 생성을 통한 정밀한 깊이 완성 기법

김석영(Seokyoung Kim),박영규(Yeonggyu Park),박태현(Taehyun Park),서유리(Yuri Seo),김찬수(Chansoo Kim),김성준(Seongjun Kim),조기춘(Kichun Jo) 한국자동차공학회 2023 한국자동차공학회 부문종합 학술대회 Vol.2023 No.5

Three-Dimensional Axotomy and Regeneration on Open-Microfluidic Device

Seokyoung Bang(방석영),Songhyun Lee(이송현),Kyeong Seob Hwang(황경섭),Jongbaeg Kim(김종백),Nakwon Choi(최낙원),Hong Nam Kim(김홍남) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.4

3D tissue formation by stacking detachable cell sheets formed on nanofiber mesh

Kim, Min Sung,Lee, Byungjun,Kim, Hong Nam,Bang, Seokyoung,Yang, Hee Seok,Kang, Seong Min,Suh, Kahp-Yang,Park, Suk-Hee,Jeon, Noo Li IOP Publishing 2017 Biofabrication Vol.9 No.1

<P>We present a novel approach for assembling 3D tissue by layer-by-layer stacking of cell sheets formed on aligned nanofiber mesh. A rigid frame was used to repeatedly collect aligned electrospun PCL (polycaprolactone) nanofiber to form a mesh structure with average distance between fibers 6.4 mm. When human umbilical vein endothelial cells (HUVECs), human foreskin dermal fibroblasts, and skeletal muscle cells (C2C12) were cultured on the nanofiber mesh, they formed confluent monolayers and could be handled as continuous cell sheets with areas 3. x. 3 cm(2) or larger. Thicker 3D tissues have been formed by stacking multiple cell sheets collected on frames that can be nested (i.e. Matryoshka dolls) without any special tools. When cultured on the nanofiber mesh, skeletal muscle, C2C12 cells oriented along the direction of the nanofibers and differentiated into uniaxially aligned multinucleated myotube. Myotube cell sheets were stacked (upto 3 layers) in alternating or aligned directions to form thicker tissue with similar to 50 mu m thickness. Sandwiching HUVEC cell sheets with two dermal fibroblast cell sheets resulted in vascularized 3D tissue. HUVECs formed extensive networks and expressed CD31, a marker of endothelial cells. Cell sheets formed on nanofiber mesh have a number of advantages, including manipulation and stacking of multiple cell sheets for constructing 3D tissue and may find applications in a variety of tissue engineering applications.</P>

Clinical manifestations and patch-test results in facial contact dermatitis induced by disposable face masks

( Seokyoung Kang ),( Jincheol Kim ),( Minje Jung ),( Boyoung Chung ),( Chunwook Park ),( Hyeone Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: The patients with facial contact dermatitis by wearing a disposable mask were rapidly increased due to the outbreak of COVID-19 Objectives: The aim of this study was to investigate the clinical manifestation and results of allergy patch test for the patients with facial contact dermatitis induced by disposable mask. Methods: The clinical manifestations, and patch-test (T.R.U.E. TEST®) results of 26 patients with contact dermatitis induced by the disposable mask (mask group) and 70 patients by other cause (control group) are investigated as a control group. Results: The skin lesion was more common in centrofacial area (69.23%) than peripheral area (30.76%). Hyperkeratosis (23.07%) and xerosis (11.53%) were more frequent in mask group. Patients in mask group complained mostly itching (57.69%) and flushing (23.07%). Patients in mask group show more positive reaction of Potassium dichromate (26.92%, [mask group] vs 10.00%, [control group]) and 4-tert-butylphenol-formaldehyde resin (15.38%, [mask group] vs 2.85%, [control group]) than control group in patch-test results. Eleven patients in control group (15.71%) were negative reaction of all items in patch-test result, in contrast only one patient showed negative reaction in mask group (3.84%). The patients of mask group showed clinical improvement after changing to cloth mask Conclusion: Patients with the facial contact dermatitis induced by disposable mask presented different contact sensitization profiles compared to control group

The clinical characteristics of the sensitive skin Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea

( Seokyoung Kang ),( Jincheol Kim ),( Minje Jung ),( Boyoung Chung ),( Chunwook Park ),( Hyeone Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Sensitive skin exhibits various clinical characteristics. Baumann classified sensitive skin into the four categories; stinging, allergic, acne and rosacea types Objectives: We aimed to investigate the clinical manifestations of sensitive skin according to the classification of Baumann Methods: With the sensitive skin scale-10, a questionnaire for measuring severity, the patients whose scores are over 50 and less than 20 were defined as sensitive skin group (n=37) and control group (n=21), respectively. Characteristics and objective measurements (transepidermal water loss [TEWL], epidermal moisture content, Von Frey filament test, demodex density) are recruited and sensitive skin group were divided according to the classification of Baumann Results: Most patients with sensitive skin were female and the mean age were 36.24 ± 11.90. The most common subtype was rosacea type followed by allergic type. Overall, the average of the TEWL in patient group was 23.21 ± 13.28, higher than control group (8.90 ± 3.09) and the reference value (14.0 ± 8.80). The epidermal moisture content of patient group was statistically lower than control group. There is no significant difference in TEWL and epidermal moisture content among subtypes. The demodex density of rosacea type is statistically higher than that of acne and stinging type Conclusion: There are distinct clinical characteristics in the four subtypes in sensitive skin. It will help to approach patients with sensitive skin

결혼 이주와 이주 수원국의 성 역할 태도: 다문화가족과 비 다문화가족 한국인 남편의 성 역할 태도 비교를 중심으로

김석영(Seokyoung Kim),김민지(Minzee Kim) 한국문화사회학회 2020 문화와 사회 Vol.28 No.2

결혼 이주 여성과 한국인 남편으로 이루어진 다문화가족은 우리 사회에서 지속적으로 증가하고 있다. 그간 다문화가족에 관한 연구는 가부장적, 상업화된 다문화결혼의 폐해와 결혼 이주 여성의 사회, 경제, 문화적인 취약성으로 인한 인권침해, 한국과 상이한 문화권에서의 이주로 인한 결혼 이주자의 적응 문제에 집중해 왔다. 반면에 결혼 이주자의 능동성과 주체성에 주목하여, 이들이 한국사회에 미치는 영향에 대한 연구는 희소한 것을 알 수 있다. 이러한 연구 경향은 다문화가족의 증가가 결혼의 주체에게 젠더 관계에 대해 새로운 문화적 이해의 문을 열어줄 수 있는 구조적 기회가 될 수도 있다는 것을 간과할 수 있다. 이에 본 연구는 다문화가족의 한국인 남편의 성 역할 태도를 비 다문화가족의 한국인 남편의 성 역할 태도와 비교해 분석했다. 분석 결과, 다문화가족의 남편들은 비 다문화가족의 남편들에 비해 육아와 가사 노동에 있어서는 덜 가부장적인 태도를 가지는 것으로 나타났고, 생계 부양과 관련해서는 더 가부장적인 태도를 가지는 것으로 나타났다. 다문화가족의 남편들의 성 역할 태도는 남편과 아내의 개인적 특성, 가족적 특성과 유의미한 관련을 가지는 것으로 나타났으나, 비 다문화가족의 남편들의 경우는 그렇지 않았다. 이는 결혼 이주의 증가가 젠더 관계에 있어 도전과 기회의 측면 모두를 가지고 있다는 것을 보여준다. For the last several decades, in addition to international mobility caused by men and women who are migrating in order to work, marriage migration has also increased. Unlike labor migration, marriage migration across the globe is predominately undertaken by women and mainly from less affluent countries to more affluent countries. Reflecting the context in which marriage migration occurs, the majority of literature on marriage migration points to the global patriarchy in which gender inequality facilitates and is reinforced by marriage migration. However, such approach could ignore structural opportunities as well as these women’s agency that could also open up a new cultural understanding regarding gender relations. In this research, we attempt to analyze marriage migration in the context of gender role attitudes of husbands in the receiving country. Using the case of Korea, we analyze gender role attitudes of Korean men married to non-Korean women and compare their attitudes with those of Korean men married to Korean women. Results show that Korean husbands in transnational marriage are not more patriarchal than Korean husbands in national marriage and that gender role attitudes of men in transnational marriage tend be explained by instrumental and familial factors while those of men in traditional marriage are not explained by either factors. This suggests both challenges and opportunities of gender relations in the era of global marriage migration. Through this analysis, we try to fill a gap in the literature by suggesting implications of marriage migration as a dynamic field in which gender roles are actively negotiated and resisted.

The clinical characteristics and courses of pityriasis rosea in Korea

( Jincheol Kim ),( Seokyoung Kang ),( Minje Jung ),( Boyoung Chung ),( Chunwook Park ),( Hyeone Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1

Background: Pityriasis rosea is an idiopathic acute or subacute inflammatory disease with diverse subtypes and clinical courses. Objectives: The aim of this study was to investigate the clinical characteristics and courses of Korean pityriasis rosea patients. Methods: The demographic features, medical history, clinical characteristics, laboratory finding and treatment modalities of 80 pityriasis rosea patients are investigated. Results: The mean age of patients was 31.8 and 63.8% (51/80) of patients were female. The secondary lesion occurs 9.7 days after the primary lesion and lasts for 49.6 days on average. The primary lesions mainly occurred on the abdomen (18.8%, [15/80]) and 46.3% (37/80) of patients did not recognize the primary lesions. The secondary lesions mostly occur on the chest (77.5%, [62/80]) and abdomen (86.3%, [69/80]) with Christmas tree pattern (93.8%, [75/80]). 21 patients (26.3%) accompanied by prodromes and 52 patients (65.0%) accompanied by pruritus which is lower than expected. Most patients were treated by antihistamine (97.5%, [78/80]), topical calcineurin inhibitor (87.5%, [70/80]) and ultraviolet therapy (87.5%, [70/80]). Conclusion: Pityriasis rosea mainly occurred on the abdomen and lasted for about 7 weeks in Koreans. The treatment duration was longer in men, non-macular subtype regardless of age, primary lesion, prodromes,and itching severity. This study provides information about the clinical course of pityriasis rosea in Korean.

TB-CompletionFormer : Two-branch Backbone 기반 향상된 깊이 완성 연구

김석영(Seokyoung Kim),김찬수(Chansoo Kim) 한국자동차공학회 2023 한국자동차공학회 학술대회 및 전시회 Vol.2023 No.11

Dense depth estimation about surrounding environments is one of the key components in autonomous driving applications such as object detection and SLAM. To predict accurate depth information, depth completion aims to predict a dense depth map from a sparse depth map by LiDAR and a RGB image by camera. In the depth completion, it is essential to effectively fuse both LiDAR and camera modalities to achieve good performance. In this paper, we propose a two-branch architecture based on Vision Transformer, which is a more powerful and accurate multi-modal backbone, to fuse different modalities from heterogeneous sensors. To fuse two modalities, the proposed model consists of two branch modules: a coarse-branch and a finebranch. Using an RGB image and a sparse depth map, the coarse-branch module generates a dense depth map focused on color information. The fine-branch module estimates a final dense depth map focused on depth information through the color-dominant depth map and the sparse depth map. Additionally, residual connections to the Joint Convolutional Attention and Transformer (JCAT) is added to preserve the feature information. As a result, experiments on NYUv2 dataset demonstrate that the proposed method outperforms the previous models.