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      • Drug adsorption and anti-microbial activity of functionalized multiwalled carbon nanotubes

        Saxena, Megha,Mittal, Disha,Boudh, Richa,Kumar, Kapinder,Verma, Anita K.,Saxena, Reena Techno-Press 2021 Advances in nano research Vol.11 No.6

        Multiwalled carbon nanotubes (MWCNTs) were first oxidized (O-CNTs) to introduce carboxylic group and then further functionalized (F-CNTs) with m-phenylenediamine, which was confirmed by FTIR and SEM. It was used as an effective adsorbent for the adsorptive removal of diclofenac drug from water. Under optimum conditions of pH 6, stirring speed 600 rpm, the maximum adsorption capacity obtained was 532 mg g<sup>-1</sup> which is superior to the values reported in literature. The adsorption was quite rapid as 25 mg L<sup>-1</sup> drug solution was adsorbed in only 3 minutes of contact time with 10 mg of adsorbent dose. The adsorption kinetics and isotherms were studied using various models to evaluate the adsorption process. The results showed that the data best fit in kinetics pseudo-second order and Langmuir isotherm model. Furthermore, the oxidized and functionalized MWCNTs were applied on gram-negative Escherichia coli and gram-positive Staphylococcus aureus using agar disc diffusion assay to validate their anti-microbial activity. Results were unique as both oxidized and functionalized MWCNTs were equally active against both E. coli and S. aureus. The newly synthesized F-CNTs have great potential in water treatment, with their dual action of removing drug and pathogens from water, makes it potential applicant to save environment.

      • Systematic review of the effectiveness of homoeopathy in the treatment of autism spectrum disorder

        Vibha Saxena,Gish Chacko,Udit Saxena 한국언어재활사협회 2021 Clinical Archives of Communication Disorders Vol.6 No.1

        Purpose: Over the years there is a significant increase in Autism Spectrum Disorder (ASD), yet there is no standard medical treatment available for this population. Homoeopathy as reported in literature can prove to be a boon for ASD treatment as in homoeopathy patients are prescribed medicine based on specific symptoms in light of associated physical and mental aspect. A systematic review of literature was required to put together the reported information on the relation between homoeopathy and ASD. This work reviews all the related literature in-depth. Methods: Literature on the concerned issue was searched from databases like Scopus, PubMed, ScienceDirect, JASTOR, Google Scholar, PsycINFO (psychology and psychiatry literature), and ERIC (Education Resources Information Center). Results: In total, 19 published articles were found on the investigation of using homoeopathy in the treatment of ASD. Seventeen studies showed that homoeopathy can be effective in the treatment of ASD. Result of 1 study was inconclusive and 1 more study found homoeopathy to be not suitable in treating ASD. Conclusions: Most reports support the use of homoeopathy in the treatment of ASD. They describe that homoeopathy efficiently control ASD symptoms and also supplements other therapies used in the treatment of ASD. Few authors suggested otherwise too.

      • KCI등재

        Assessment of Genetic Diversity in Cabbage Cultivars Using RAPD and SSR Markers

        Saxena, Bhawna,Kaur, Rajinder,Bhardwaj, Satya Vrat 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.3

        Genetic relationship and diversity among seven cabbage cultivars were analyzed using RAPD and SSR markers. These cultivars are of great commercial value in India and are confirmed for their reaction to black rot caused by Xanthomonas campestris pv. campestris. However, so far the extent of genetic diversity and relatedness has not been studied in these cultivars. A total of 17 selected RAPD primers generated 90 bands, 76 of which were polymorphic (84.44%). In addition, 27 selected SSR primers generated 67 amplified bands with 59 of which were polymorphic (87.6%). Though both the marker techniques were able to discriminate the cultivars effectively, analysis of combined data of markers (RAPD and SSR) resulted in better distinction of cultivars. By combining both the markers, a total of 157 bands were detected of which 135 bands (85.98%) were polymorphic, i.e. an average of 5.95 bands per primer. High level of polymorphism (> 85%) recorded with two different marker systems indicated a high level of genetic variation existing among the cultivars. Genetic relationship estimated using similarity co-efficient (Jaccard's) values between different pairs of cultivars varied from 0.21 to 0.77 in RAPD, 0.42 to 0.82 in SSR, and 0.43 to 0.89 with combined markers. A high correspondence had been recorded between the values of genetic variations generated by UPGMA, clustering, and scatter plot diagrams. The cultivars 'January King Sel. Improved' and 'Golden Acre' are highly divergent cultivars as demonstrated by both the marker systems.

      • QuESt: a QoS-based energy efficient sensor routing protocol

        Saxena, Navrati,Roy, Abhishek,Shin, Jitae John Wiley Sons, Ltd. 2009 WIRELESS COMMUNICATIONS AND MOBILE COMPUTING Vol.9 No.3

        <P>Rapid penetration of smart wireless devices and enormous growth of wireless communication technologies has already set the stage for deployment of wireless sensor networks (WSNs). While these small sensor nodes are often considered as the future of wireless communications, they also suffer from energy constraints. On the other hand, with increasing demand for real-time services in next generation wireless networks, quality-of-service (QoS)-based routing has emerged as an interesting research topic. Naturally offering some QoS-guarantee in sensor networks raises significant challenges. The network needs to cope up with battery-constraints, while providing precise QoS (end-to-end delay and bandwidth requirement) guarantee. More precisely, designing such QoS-protocols, optimizing multiple objectives, is computationally intractable. Based on the multi-objective genetic algorithm (MOGA), in this paper we propose a QoS-based energy-efficient sensor routing (QuESt) protocol that determines application-specific, near-optimal sensory-routes demand, by optimizing multiple QoS parameters, (end-to-end delay and bandwidth requirements) and energy consumption. Simulation results demonstrate that the proposed protocol is capable of discovering a set of QoS-based, near-optimal routes, even with imprecise network information. Copyright © 2007 John Wiley & Sons, Ltd.</P>

      • Near-Optimal Auto-Configuration of PCID in LTE Cellular Systems

        SAXENA, Navrati,ROY, Abhishek,WON, Jeong Jae The Institute of Electronics, Information and Comm 2009 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.92 No.10

        <P>In this letter we show that the dynamic optimal PCID allocation problem in LTE systems is NP-complete. Subsequently we provide a near-optimal solution using SON which models the problem using new merge operations and explores the search space using a suitable randomized algorithmic approach. Two feasible options for dynamic auto-configuration of the system are also discussed. Simulation results point out that the approach provides near-optimal auto-configuration of PCIDs in computationally feasible time.</P>

      • A New Channel-Aware Rate Adaptation in High Speed WLANs

        SAXENA, Navrati,ROY, Abhishek The Institute of Electronics, Information and Comm 2009 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.92 No.6

        <P>In this letter we propose an advanced rate adaptation algorithm that intelligently uses the channel statistics to make fast and efficient selection of transmission rates. Our implementation and simulation results prove that the proposed strategy achieves major latency and throughput improvements on 802.11n products and existing related protocols. The entire work is on a software module, thus providing adaptability, cost-effectiveness, with no hardware changes.</P>

      • Efficient IoT Gateway over 5G Wireless: A New Design with Prototype and Implementation Results

        Saxena, Navrati,Roy, Abhishek,Sahu, Bharat J. R.,Kim, HanSeok IEEE 2017 IEEE communications magazine Vol.55 No.2

        <P>The growth of loT is expected to herald a better quality of life and open up new industrial opportunities. However, it is also raising new challenges in resource constrained wireless networks. Originally designed for human-to-human wireless communications, present wireless networks fail to satisfy the huge connectivity and varying traffic requirements of loT. Next generation 5G wireless networks are expected to exploit emerging features, like mmWave, massive MIMO, and C-RAN, for providing the enormous connectivity, resource pooling, and energy efficiency required to support commercial rollout of loT. Exploring these emerging features, we develop 5G-enabled loT gateways to communicate with the RRI Is of 5G C: RAN. The gateways are endowed with efficient compression schemes to significantly improve uplink resource utilization. Our 5G C-RAN prototyping and laboratory experimental results point out a huge opportunity for supporting a massive number of loT-enabled devices by sophisticated 5G C-RAN deployment and efficient loT gateway development.</P>

      • Active VM Consolidation for Cloud Data Centers under Energy Saving Approach

        Saxena, Shailesh,Khan, Mohammad Zubair,Singh, Ravendra,Noorwali, Abdulfattah International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.11

        Cloud computing represent a new era of computing that's forms through the combination of service-oriented architecture (SOA), Internet and grid computing with virtualization technology. Virtualization is a concept through which every cloud is enable to provide on-demand services to the users. Most IT service provider adopt cloud based services for their users to meet the high demand of computation, as it is most flexible, reliable and scalable technology. Energy based performance tradeoff become the main challenge in cloud computing, as its acceptance and popularity increases day by day. Cloud data centers required a huge amount of power supply to the virtualization of servers for maintain on- demand high computing. High power demand increase the energy cost of service providers as well as it also harm the environment through the emission of CO<sub>2</sub>. An optimization of cloud computing based on energy-performance tradeoff is required to obtain the balance between energy saving and QoS (quality of services) policies of cloud. A study about power usage of resources in cloud data centers based on workload assign to them, says that an idle server consume near about 50% of its peak utilization power [1]. Therefore, more number of underutilized servers in any cloud data center is responsible to reduce the energy performance tradeoff. To handle this issue, a lots of research proposed as energy efficient algorithms for minimize the consumption of energy and also maintain the SLA (service level agreement) at a satisfactory level. VM (virtual machine) consolidation is one such technique that ensured about the balance of energy based SLA. In the scope of this paper, we explore reinforcement with fuzzy logic (RFL) for VM consolidation to achieve energy based SLA. In this proposed RFL based active VM consolidation, the primary objective is to manage physical server (PS) nodes in order to avoid over-utilized and under-utilized, and to optimize the placement of VMs. A dynamic threshold (based on RFL) is proposed for over-utilized PS detection. For over-utilized PS, a VM selection policy based on fuzzy logic is proposed, which selects VM for migration to maintain the balance of SLA. Additionally, it incorporate VM placement policy through categorization of non-overutilized servers as- balanced, under-utilized and critical. CloudSim toolkit is used to simulate the proposed work on real-world work load traces of CoMon Project define by PlanetLab. Simulation results shows that the proposed policies is most energy efficient compared to others in terms of reduction in both electricity usage and SLA violation.

      • Authentication and Authorization Scheme for Various User Roles and Devices in Smart Grid

        Saxena, Neetesh,Bong Jun Choi,Rongxing Lu IEEE 2016 IEEE transactions on information forensics and sec Vol.11 No.5

        <P>The smart grid, as the next generation of the power grid, is characterized by employing many different types of intelligent devices, such as intelligent electronic devices located at substations, smart meters positioned in the home area network, and outdoor field equipment deployed in the fields. In addition, there are various users in the smart grid network, including customers, operators, maintenance personnel, and so on, who use these devices for various purposes. Therefore, a secure and efficient mutual authentication and authorization scheme is needed in the smart grid to prevent various insider and outsider attacks on many different devices. In this paper, we propose an authentication and authorization scheme for mitigating outsider and insider threats in the smart grid by verifying the user authorization and performing the user authentication together whenever a user accesses the devices. The proposed scheme computes each user role dynamically using an attribute-based access control and verifies the identity of the user together with the device. Security and performance analysis show that the proposed scheme resists various insider as well as outsider attacks, and is more efficient in terms of communication and computation costs in comparison with the existing schemes. The correctness of the proposed scheme is also proved using BAN-Logic and Proverif.</P>

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