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      • Parametric Surface Defined on Parallelogrammic Domain and its Properties

        FAN Shuqian,ZOU Jinsong,SHI Mingquan (사)한국CDE학회 2013 한국CAD/CAM학회 국제학술발표 논문집 Vol.2010 No.8

        As essential components of many mechanical systems, tooth geometrical properties of spiral bevel gears greatly influence on the kinematic and dynamic behaviors of mechanical systems. Logarithmic spiral bevel gears show unique advantage in transmission due to their constant spiral angle property. However, mathematical model suitable for accurate digital modeling, differential geometrical characteristics and related contact analysis methods of tooth surface have not been deeply investigated, since such gears are not convenient to traditional cutting manufacture in gear industry. An accurate mathematical modeling of the tooth surface geometry for logarithmic spiral bevel gears is developed, based on the basic gearing kinematics and spherical involute geometry along with the tangent planes geometry. Actually, the tooth surface is a parametric surface defined on parallelogrammic domain. Then, an equivalence proof of the tooth surface geometry is given in order to greatly simplify the mathematical model. As major factors affecting lubrication, surface fatigue, contact stress, wear and manufacturability of gear teeth, differential geometrical characteristics of the tooth surface is summarized employing classical fundamental forms. By using mentioned geometrical properties, manufacturability and its limitation of logarithmic spiral bevel gears is analyzed using precision forging and multi-axis freeform milling, instead of classical cradle-type machine tools based milling or hobbing. Geometry and manufacturability analysis result shows that logarithmic spiral gears have many application advantages, but many urgent issues such as contact tooth analysis for precision plastic forming and multi-axis freeform milling should be further solved.

      • KCI등재

        Parametric surface and properties defined on parallelogrammic domain

        Fan, Shuqian,Zou, Jinsong,Shi, Mingquan Society for Computational Design and Engineering 2014 Journal of computational design and engineering Vol.1 No.1

        Similar to the essential components of many mechanical systems, the geometrical properties of the teeth of spiral bevel gears greatly influence the kinematic and dynamic behaviors of mechanical systems. Logarithmic spiral bevel gears show a unique advantage in transmission due to their constant spiral angle property. However, a mathematical model suitable for accurate digital modeling, differential geometrical characteristics, and related contact analysis methods for tooth surfaces have not been deeply investigated, since such gears are not convenient in traditional cutting manufacturing in the gear industry. Accurate mathematical modeling of the tooth surface geometry for logarithmic spiral bevel gears is developed in this study, based on the basic gearing kinematics and spherical involute geometry along with the tangent planes geometry; actually, the tooth surface is a parametric surface defined on a parallelogrammic domain. Equivalence proof of the tooth surface geometry is then given in order to greatly simplify the mathematical model. As major factors affecting the lubrication, surface fatigue, contact stress, wear, and manufacturability of gear teeth, the differential geometrical characteristics of the tooth surface are summarized using classical fundamental forms. By using the geometrical properties mentioned, manufacturability (and its limitation in logarithmic spiral bevel gears) is analyzed using precision forging and multiaxis freeform milling, rather than classical cradle-type machine tool based milling or hobbing. Geometry and manufacturability analysis results show that logarithmic spiral gears have many application advantages, but many urgent issues such as contact tooth analysis for precision plastic forming and multiaxis freeform milling also need to be solved in a further study.

      • KCI등재

        Serum MicroRNA Levels as a Noninvasive Diagnostic Biomarker for the Early Diagnosis of Hepatitis B Virus-Related Liver Fibrosis

        ( Suxia Bao ),( Jianming Zheng ),( Ning Li ),( Chong Huang ),( Mingquan Chen ),( Qi Cheng ),( Kangkang Yu ),( Shengshen Chen ),( Mengqi Zhu ),( Guangfeng Shi ) 대한간학회 2017 Gut and Liver Vol.11 No.6

        Background/Aims: To investigate the role of selected serum microRNA (miRNA) levels as potential noninvasive biomarkers for differentiating S0-S2 (early fibrosis) from S3-S4 (late fibrosis) in patients with a chronic hepatitis B virus (HBV) infection. Methods: One hundred twenty-three treatment-naive patients with a chronic HBV infection who underwent a liver biopsy were enrolled in this study. The levels of selected miRNAs were measured using a real-time quantitative polymerase chain reaction assay. A logistic regression analysis was performed to assess factors associated with fibrosis progression. Receiver operating characteristic (ROC) curve and discriminant analyses validated these the ability of these predicted variables to discriminate S0-S2 from S3-S4. Results: Serum miR-29, miR-143, miR-223, miR-21, and miR-374 levels were significantly downregulated as fibrosis progressed from S0-S2 to S3-S4 (p<0.05), but not miR-16. The multivariate logistic regression analysis identified a panel of three miRNAs and platelets that were associated with a high diagnostic accuracy in discriminating S0-S2 from S3-S4, with an area under the curve of 0.936. Conclusions: The levels of the studied miRNAs, with the exception of miR-16, varied with fibrosis progression. A panel was identified that was capable of discriminating S0-S2 from S3-S4, indicating that serum miRNA levels could serve as a potential noninvasive biomarker of fibrosis progression. (Gut Liver 2017;11:860-869)

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