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RISS 인기검색어
- 검색키워드
- 저자 : S.S.ROUTRAY (검색결과 3 건)
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A NOTE ON OPTIMAL ORDER LEVEL FOR DETERIORATING ITEMS WITH UNIFORM DEMAND RATE
S.S.ROUTRAY,S.K.PAIKRAY,U.K.MISRA 장전수학회 2014 Proceedings of the Jangjeon mathematical society Vol.17 No.3
An optimal order level inventory problem is discussed with the uniform demand rate. It is assumed that the inventory system deals with three types of items with uniform demand rate and shortages are allowed. The scheduled time is xed for all the items deteriorate at a time varying rate. There is no repair or replacement of deteriorated items during the given cycle. In this problem we have taken mixed seasonal, non seasonal and purely seasonal items which are stored at own as well as rented ware houses. A numerical example is taken up to illustrate the solution procedure.
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Ndonwi, Elvis Ngwa,Atogho-Tiedeu, Barbara,Lontchi-Yimagou, Eric,Shinkafi, Tijjani S.,Nanfa, Dieudonne,Balti, Eric V.,Indusmita, Routray,Mahmood, Amena,Katte, Jean-Claude,Mbanya, Armand,Matsha, Tandi,M Korean Society of ToxicologyKorea Environmental Mu 2019 Toxicological Research Vol.35 No.3
Pesticide exposure may induce biochemical alterations including oxidative stress and lipid peroxidation. However, in the context of developmental origin of health and disease, putative trans-generational effect of exposure to pesticides are insufficiently studied. We therefore aimed to evaluate the biochemical effect of gestational exposure to four pesticides on female Wistar rats and their offspring at adult age. We studied 30 female nulliparous Wistar rats divided into 5 equal groups. Group 1 served as the control group and received distilled water while group 2, 3, 4 and 5 received orally pesticide 1 (imidacloprid), pesticide 2 (chlorpyrifos), pesticide 3 (imidacloprid + lambda cyhalothrin) and pesticide 4 (oxamyl) respectively once daily throughout gestation at a dose equivalent to 1/10 lethal dose 50. The mothers were followed up until one month post gestation. The offspring were followed up from birth until adult age (12 weeks). In all animals at each time point we evaluated malondialdehyde (MDA), oxidative stress and liver function enzymes. There was similar variation of total body weight in all the groups during and after gestation. However, Female Wistar rats of the exposed groups had significant alterations in liver SOD (-30.8% to +64.1%), catalase (-38.8% to -85.7%) and GSH (-29.2% to -86.5%) and; kidney catalase (> 100%), GSH (> 100%). Moreover, MDA, alanine transaminase (ALT) and aspartate transaminase (AST) levels were significantly higher in pesticide exposed rats compared to the control group. Similar alterations in antioxidant enzymes, MDA and liver function enzymes were observed in offspring of treated rats evidenced at weaning and persisting until adult age. Exposure to pesticides causes oxidative stress and lipid peroxidation in exposed female Wistar rats and their offspring. The persistence in offspring at adult age suggests transgenerational adverse effects.
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Elvis Ngwa Ndonwi,Barbara Atogho-Tiedeu,Eric Lontchi-Yimagou,Tijjani S. Shinkafi,Dieudonne Nanfa,Eric V. Balti,Routray Indusmita,Amena Mahmood,Jean-Claude Katte,Armand Mbanya,Tandi Matsha,Jean Claude 한국독성학회 2019 Toxicological Research Vol.35 No.3
Pesticide exposure may induce biochemical alterations including oxidative stress and lipid peroxidation. However, in the context of developmental origin of health and disease, putative trans-generational effect of exposure to pesticides are insufficiently studied. We therefore aimed to evaluate the biochemical effect of gestational exposure to four pesticides on female Wistar rats and their offspring at adult age. We studied 30 female nulliparous Wistar rats divided into 5 equal groups. Group 1 served as the control group and received distilled water while group 2, 3, 4 and 5 received orally pesticide 1 (imidacloprid), pesticide 2 (chlorpyrifos), pesticide 3 (imidacloprid + lambda cyhalothrin) and pesticide 4 (oxamyl) respectively once daily throughout gestation at a dose equivalent to 1/10 lethal dose 50. The mothers were followed up until one month post gestation. The offspring were followed up from birth until adult age (12 weeks). In all animals at each time point we evaluated malondialdehyde (MDA), oxidative stress and liver function enzymes. There was similar variation of total body weight in all the groups during and after gestation. However, Female Wistar rats of the exposed groups had significant alterations in liver SOD (−30.8% to +64.1%), catalase (−38.8% to −85.7%) and GSH (−29.2% to −86.5%) and; kidney catalase (> 100%), GSH (> 100%). Moreover, MDA, alanine transaminase (ALT) and aspartate transaminase (AST) levels were significantly higher in pesticide exposed rats compared to the control group. Similar alterations in antioxidant enzymes, MDA and liver function enzymes were observed in offspring of treated rats evidenced at weaning and persisting until adult age. Exposure to pesticides causes oxidative stress and lipid peroxidation in exposed female Wistar rats and their offspring. The persistence in offspring at adult age suggests transgenerational adverse effects.
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