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Aljoša Trmčić,John Samelis,Christophe Monnet,Irena Rogelj,Bojana Bogovič Matijašić 한국유전학회 2011 Genes & Genomics Vol.33 No.3
Nisin is an antimicrobial peptide produced by Lactococcus lactis. It has a long history of safe use, mainly in food production. This bacteriocin has been studied from many aspects of genetics, biosynthesis, immunity, regulation and mode of action. The strain Lac. lactis M78 has already been described in previous studies as a good nisin A producer with equally good potential to be used in food production. The main objective of the present study was to determine the complete nucleic acid sequence of the nisin A gene cluster from this strain. This is the first time that all 11 genes that form the nisin A gene cluster were sequenced. The obtained sequence (GenBank: HM219853) was compared to other known nucleic acid sequences of bacteriocin nisin. The results of the comparison showed certain differences in sequences that might influence the structure and function of proteins involved in nisin biosynthesis, immunity and regulation.
Biophysical and economic limits to negative CO<sub>2</sub> emissions
Smith, Pete,Davis, Steven J.,Creutzig, Felix,Fuss, Sabine,Minx, Jan,Gabrielle, Benoit,Kato, Etsushi,Jackson, Robert B.,Cowie, Annette,Kriegler, Elmar,van Vuuren, Detlef P.,Rogelj, Joeri,Ciais, Philipp Nature Publishing Group 2016 Nature climate change Vol.6 No.1
<P>To have a >50% chance of limiting warming below 2 degrees C, most recent scenarios from integrated assessment models (IAMs) require large-scale deployment of negative emissions technologies (NETs). These are technologies that result in the net removal of greenhouse gases from the atmosphere. We quantify potential global impacts of the different NETs on various factors (such as land, greenhouse gas emissions, water, albedo, nutrients and energy) to determine the biophysical limits to, and economic costs of, their widespread application. Resource implications vary between technologies and need to be satisfactorily addressed if NETs are to have a significant role in achieving climate goals.</P>