Toward an intelligent approach for predicting surface tension of binary mixtures containing ionic liquids

Reza Soleimani,Amir Hossein Saeedi Dehaghani,Navid Alavi Shoushtari,Pedram Yaghoubi,Alireza Bahadori 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.7

Knowledge of the surface tension of ionic liquids (ILs) and their related mixtures is of central importance and enables engineers to efficiently design new processes dealing with these fluids on an industrial scale. It’s obvious that experimental determination of surface tension of every conceivable IL and its mixture with other compounds would be a herculean task. Besides, experimental measurements are intrinsically laborious and expensive; therefore, accurate prediction of the property using a reliable technique would be overwhelmingly favorable. To do so, a modeling method based on artificial neural network (ANN) trained by Bayesian regulation back propagation training algorithm (trainbr) has been proposed to predict surface tension of the binary ILs mixtures. A total set of 748 data points of binary surface tension of IL systems within temperature range of 283.1-348.15 K was used to train and test the applied network. The obtained results indicated that the predictive values and experimental data are quite matching, representing reliability of the used ANN model for such purpose. Also, compared with other methods, such as SVM, GA-SVM, GA-LSSVM, CSA-LSSVM, GMDH-PNN and ANN trained with trainlm algorithm the proposed model was better in terms of accuracy.

Study effect of different parameters on the sulphate sorption onto nano alumina

Reza Katal,Mehdi Jafari,Amir Hossein Saeedi Dehaghani,Seyedmehdi Sharifian,Mohammed Ali Ghayyem,Mohsen Vafaie Sefti 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.1

The aim of this research work is to investigate sorption characteristic of modified nano alumina (n-Al) for the removal of SO42 from aqueous solutions and wastewater. The sorption of SO42 by batch method is carried out. The optimum conditions of sorption were found to be: a sorbent dose of 0.3 g in 100 ml of SO42, contact time of 35 min, pH = 5. In optimum condition, removal efficiency was 85.6% for the SO42. Three equations, i.e. Morris–Weber, Lagergren and pseudo second order have been tested to track the kinetics of removal process. The Langmuir, Freundlich and D–R are subjected to sorption data to estimate sorption capacity. It can be concluded that n-Al has potential to remove SO42 ions from aqueous solutions at different concentrations. It was found that the temperature has positive effect on the process and negative DG values indicated thermodynamically feasible and spontaneous nature of the sorption. Positive value of DS reveals the increased randomness at the solid–solution interface during the fixation of the ion on the active sites of the sorbent. The effect of other anions was studied and it was found the existence of them in the solution has considerable effect on the sulphate removal.

The Impact of MRS Phantom Container on the Quality of Spectrum Provided by 3T MRI

Mahdi Saeedi-Moghadam,Mehrzad Lotfi,Banafsheh Zeinali-Rafsanjani,Reza Jalli 한국자기학회 2020 Journal of Magnetics Vol.25 No.3

This study intended to evaluate the effect of the material of phantom-container on the MRS signal in 3T MRI. Three phantom-container consisting of clear laboratory-glass, PET-bottle, and falcon-tube was used. The metabolites contained 6 mM Cr and 3 mM Cho. FWHM and SNR of Cho and both peaks of Cr were calculated. FWHM of all the peaks of glass-phantom was 50.08 and 19.48 % fewer than those provided by PET and falcon-tube; also, the SNR of the all the peaks of the PET and falcon-tube were by average 77.99 and 91.18 % fewer than the peaks provided by glass-phantom. The laboratory-glass is a good material for building MRS phantoms since it does not affect the baseline-noise, FWHM, and SNR of the spectra. It was also revealed that the size of the phantom and the distance between the spectroscopy volume and phantom walls were important and can affect the baseline-noise.

Assessment the Influencing Factors on MRS Signal Obtained from High Magnetic Field Strength (1.5T) MRI Scanners During the Application of Homemade Metabolite Phantom

Mahdi Saeedi-Moghadam,Majid Pouladian,Mehrzad Lotfi,Reza Faghihi 한국자기학회 2019 Journal of Magnetics Vol.24 No.1

Purpose: This study aimed to present a protocol for constructing MRS phantoms that are supposed to be subjective of spectroscopy using 1.5T machines. Methods: As phantom containers, laboratory clear/amber glass bottles and an internally-designed Plexiglass and PVC cylinders were tested to evaluate the effect of phantom material and design on produced signals. HPLC and distilled-water were evaluated as solvent of metabolites. Finally, a protocol was suggested. Results: The results revealed that the physical walls of internally-designed phantom affect the WS and its baseline noise. The results also showed that even the amber-pigments inside the bottles can affect the MRS signal. Accordingly, the combination of HPLC-water inside clear-glass containers is suggested. Conclusion: The suggested protocol is as follows, apply clear-glass container as phantom body, do not build internal-structures using physical walls of glass or any other materials. Apply HPLC-water as solvent instead of distilled-water. Check the purity of chemical metabolites.

CO2/CH4 separation with poly(4-methyl-1-pentyne) (TPX) based mixed matrix membrane filled with Al2O3 nanoparticles

Amir Hossein Saeedi Dehaghani,Mohammad Hadi Nematollahi,Reza Abedini 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.2

The effect of alumina (Al2O3) nano-particles on gas separation properties of poly(4-methyl-1-pentyne) known as TPX was evaluated. Mixed matrix membranes (MMMs) were prepared with various weight percent (5, 10, 15, 20 and 30) of alumina nano-particles through solution casting along with solvent evaporation method. TPX and consequent MMMs were characterized using FT-IR, SEM and TGA methods. The MMMs permselectivities were determined through pure CO2 and CH4 permeation measurement and CO2/CH4 selectivity calculation. SEM images demonstrated the proper dispersion of alumina nano-particles in TPX matrix. Results from gas permeation showed that the permeability of both CO2 and CH4 as well as CO2/CH4 selectivities were increased with increasing alumina content. Significant increase of CO2 permeability (from 157.43 Barrer at 8 bar and no loading of Al2O3 to 527.78 Barrer at 8 bar and 30 wt% loading of Al2O3) and conspicuous enhancement of selectivity, from 7.73 to 12.51, were obtained in TPX MMMs.

Survival Analysis of Patients with Breast Cancer using Weibull Parametric Model

Baghestani, Ahmad Reza,Moghaddam, Sahar Saeedi,Majd, Hamid Alavi,Akbari, Mohammad Esmaeil,Nafissi, Nahid,Gohari, Kimiya Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

Background: The Cox model is known as one of the most frequently-used methods for analyzing survival data. However, in some situations parametric methods may provide better estimates. In this study, a Weibull parametric model was employed to assess possible prognostic factors that may affect the survival of patients with breast cancer. Materials and Methods: We studied 438 patients with breast cancer who visited and were treated at the Cancer Research Center in Shahid Beheshti University of Medical Sciences during 1992 to 2012; the patients were followed up until October 2014. Patients or family members were contacted via telephone calls to confirm whether they were still alive. Clinical, pathological, and biological variables as potential prognostic factors were entered in univariate and multivariate analyses. The log-rank test and the Weibull parametric model with a forward approach, respectively, were used for univariate and multivariate analyses. All analyses were performed using STATA version 11. A P-value lower than 0.05 was defined as significant. Results: On univariate analysis, age at diagnosis, level of education, type of surgery, lymph node status, tumor size, stage, histologic grade, estrogen receptor, progesterone receptor, and lymphovascular invasion had a statistically significant effect on survival time. On multivariate analysis, lymph node status, stage, histologic grade, and lymphovascular invasion were statistically significant. The one-year overall survival rate was 98%. Conclusions: Based on these data and using Weibull parametric model with a forward approach, we found out that patients with lymphovascular invasion were at 2.13 times greater risk of death due to breast cancer.

Application of a Non-Mixture Cure Rate Model for Analyzing Survival of Patients with Breast Cancer

Baghestani, Ahmad Reza,Moghaddam, Sahar Saeedi,Majd, Hamid Alavi,Akbari, Mohammad Esmaeil,Nafissi, Nahid,Gohari, Kimiya Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16

Background: As a result of significant progress made in treatment of many types of cancers during the last few decades, there have been an increased number of patients who do not experience mortality. We refer to these observations as cure or immune and models for survival data which include cure fraction are known as cure rate models or long-term survival models. Materials and Methods: In this study we used the data collected from 438 female patients with breast cancer registered in the Cancer Research Center in Shahid Beheshti University of Medical Sciences, Tehran, Iran. The patients had been diagnosed from 1992 to 2012 and were followed up until October 2014. We had to exclude some because of incomplete information. Phone calls were made to confirm whether the patients were still alive or not. Deaths due to breast cancer were regarded as failure. To identify clinical, pathological, and biological characteristics of patients that might have had an effect on survival of the patients we used a non-mixture cure rate model; in addition, a Weibull distribution was proposed for the survival time. Analyses were performed using STATA version 14. The significance level was set at $P{\leq}0.05$. Results: A total of 75 patients (17.1%) died due to breast cancer during the study, up to the last follow-up. Numbers of metastatic lymph nodes and histologic grade were significant factors. The cure fraction was estimated to be 58%. Conclusions: When a cure fraction is not available, the analysis will be changed to standard approaches of survival analysis; however when the data indicate that the cure fraction is available, we suggest analysis of survival data via cure models.

Intronic Polymorphisms of the SMAD7 Gene in Association with Colorectal Cancer

Damavand, Behzad,Derakhshani, Shaghayegh,Saeedi, Nastaran,Mohebbi, Seyed Reza,Milanizadeh, Saman,Azimzadeh, Pedram,Aghdaie, Hamid Asadzadeh,Zali, Mohammad Reza Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

Based on genome-wide association studies (GWAS) a linkage between several variants such as single nucleotide polymorphisms (SNPs) in intron 3 of SMAD7 (mothers against decapentaplegic homolog7) were, rs12953717, rs4464148 and rs4939827 has been noted for susceptibility to colorectal cancer (CRC). In this study we investigated the relationship of rs12953717 and rs4464148 with risk of CRC among 487 Iranian individuals based on a case-control study. Genotyping of SNPs was performed by PCR-RFLP and for confirming the outcomes, 10% of genotyping cases were sequenced with RFLP. Comparing the case and control group, we have found significant association between the rs4464148 SNP and lower risk of CRC. The AG genotype showed decreased risk with and odds ratio of 0.635 (adjusted OR=0.635, 95% CI: 0.417-0.967, p=0.034). There was no significant difference in the distribution of SMAD7 gene rs12953717 TT genotype between two groups of the population evaluated (adjusted OR=1.604, 95% CI: 0.978-2.633, p=0.061). On the other hand, rs12953717 T allele showed a statistically significant association with CRC risk (adjusted OR=1.339, 95% CI: 1.017-1.764, p=0.037). In conclusion, we found a significant association between CRC risk and the rs4464148 AG genotype. Furthermore, the rs12953717 T allele may act as a risk factor. This association may be caused by alternative splicing of pre mRNA. Although we observed a strong association with rs4464148 GG genotype in affected women, we did not detect the same association in CRC male patients.

Purification and removal of Ascaris and Fasciola hepatica eggs from drinking water using roughing filters

Amir Hossein Mahvi,Jafar Nouri,Reza Saeedi,Kavoos Dindarloo,Mohammad Rafiee,Sina Dobaradaran 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.3

The performance of a horizontal roughing filter (HRF) and a downflow roughing filter (DRF) in the removal of Ascaris and Fasciola hepatica eggs was investigated. The experiments were performed at three filtration rates of 0.5, 1.0 and 1.5 m/h and different influent concentrations of Ascaris and Fasciola hepatica eggs. Alteration of the filtration rate in the range of 0.5-1.5 m/h did not have significant influence on the effectiveness of the roughing filters. The HRF had higher efficiency in the removal of both Fasciola hepatica and Ascaris eggs in comparison with the DRF, so that the average efficiencies of the HRF for the removal of Fasciola hepatica and Ascaris eggs at filtration rate of 1.0m/h were determined to be 89.0 and 57.3%, respectively, whereas the same values of the DRF were 77.2 and 52.5%, respectively. The straining was confirmed to be the main mechanism of helminth eggs removal by the roughing filters, because Fasciola hepatica eggs with larger size were removed more effectively than Ascaris eggs. The results of this study indicate that the roughing filters, especially the HRF, had promising performance in the removal of helminth eggs and could be used for water and secondary effluent treatment.