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      • KCI등재

        Editing, Publishing and Aggregating Video Articles: Do We Need a Scholarly Approach?

        Reza Assadi,Armen Yuri Gasparyan 대한의학회 2015 Journal of Korean medical science Vol.30 No.9

        The article supports the idea of providing infrastructure and training for preparing and publishing quality video articles. Properly edited, formatted, and verified video items can present graphic contents of interest to the global scientific community. It is suggested to apply traditional attributes of scholarly articles to video items and aggregate them on a specifically designed editing, publishing, and indexing platform, called PubTube. As a mega platform, PubTube may provide space for a variety of open-access sources of information, ranging from short audio-video presentations to research protocols and educational lectures. Video articles on the platform have to pass quality checks by skilled reviewers. Global editorial associations should be prepared to improving the whole process of publishing and aggregating video articles.

      • Template-oriented synthesis of hydroxyapatite nanoplates for 3D bone printing

        Doustkhah, Esmail,Najafi Zare, Reza,Yamauchi, Yusuke,Taheri-Kafrani, Asghar,Mohtasham, Hamed,Esmat, Mohamed,Ide, Yusuke,Fukata, Naoki,Rostamnia, Sadegh,Sadeghi, Morteza H.,Assadi, M. Hussein N. Royal Society of Chemistry 2019 Journal of Materials Chemistry B Vol. No.

        <P>The design of hydroxyapatite (HA) nanoarchitecture is critical for fabricating artificial bone tissues as it dictates the biochemical and the mechanical properties of the final product. Herein, we incorporated a simple hard-template approach to synthesise single crystal nanoplates of HA. We used the 2D graphitic nitride (g-C3N4) material to prepare an HA sol-gel under hydrothermal conditions. A new HA nanostructure was then formed during the calcination and removal of g-C3N4 at a higher temperature, which finally led to the production of nanoplates (thickness of ∼100 nm) while in lateral dimension the average size was in the micrometre scale. We characterised the synthesised HA nanoplates with XRD, TEM, and HRTEM. The theoretically predicted nanostructure construction based on Wulff's method is in full agreement with the experimental observations. We then prepared different weight ratios of HA and polylactic acid (PLA) composites for artificial 3D bone fabrication. The strong interaction between PLA and HA's (110) facet, which was the second most prevalent, resulted in the composite's mechanical robustness. After mechanical testing, an optimum ratio was selected for biological studies and 3D printing. Biological experiments demonstrated that the synthesised composite had excellent viability <I>in vitro</I>.</P>

      • KCI등재

        Radioimmunotherapy (RIT) in Brain Tumors

        Ali Gholamrezanezhad,Hossein Shooli,Narges Jokar,Reza Nemati,Majid Assadi 대한핵의학회 2019 핵의학 분자영상 Vol.53 No.6

        Annually, the incidence of brain tumors has slightly increased and also the patient prognosis is still disappointing, especially for high-grade neoplasms. So, researchers seek methods to improve therapeutic index as a critical aim of treatment. One of these new challenging methods is radioimmunotherapy (RIT) that involves recruiting a coupling of radionuclide component with monoclonal antibody (mAb) which are targeted against cell surface tumor–related antigens or antigens of cells within the tumor microenvironment. In the context of cancer care, precision medicine is exemplified by RIT; precision medicine can offer a tailored treatment to meet the needs for treatment of brain tumors. This review aims to discuss the molecular targets used in radioimmunotherapy of brain tumors, available and future radioimmunopharmaceutics, clinical trials of radioimmunotherapy in brain neoplasms, and eventually, conclusion and future perspective of application of radioimmunotherapy in neurooncology cancer care.

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