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      • Decreased Expression of FADS1 Predicts a Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma

        Du, Yong,Yan, Shu-Mei,Gu, Wan-Yi,He, Fan,Huang, Li-Yun,Li, Mei,Yuan, Yan,Chen, Ren-Hui,Zhong, Qian,Li, Man-Zhi,Li, Yong,Zeng, Mu-Sheng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

        FADS1 (fatty acid desaturase 1) plays a crucial role in fatty acid metabolism, and it was recently reported to be involved in tumorigenesis. However, the role of FADS1 expression in esophageal squamous cell carcinoma (ESCC) remains unknown. In the current study, we investigated the expression and clinical pathologic and prognostic significance of FADS1 in ESCC. Immunohistochemical analyses revealed that 58.2% (146/251) of the ESCC tissues had low levels of FADS1 expression, whereas 41.8% (105/251) exhibited high levels of FADS1 expression. In positive cases, FADS1 expression was detected in the cytoplasm of cells. Correlation analyses demonstrated that FADS1 expression was significantly correlated with tumor location (p=0.025) but not with age, gender, histological grade, tumor status, nodal status or TNM staging. Furthermore, patients with tumors expressing high levels of FADS1had a longer disease-free survival time (p<0.001) and overall survival time (p <0.001). Univariate and multivariate analyses revealed that, along with nodal status, FADS1 expression was an independent and significant predictive factor (p<0.001). In conclusion, our study suggested that FADS1 might be a valuable biomarker and potential therapeutic target for ESCC.

      • KCI등재

        MR Imaging of the Spine at 3.0T with T2-Weighted IDEAL Fast Recovery Fast Spin-Echo Technique

        Ai-Jun Ren,Yong Guo,Shu-Ping Tian,Li-Jing Shi,Min-Hua Huang 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.1

        Objective: To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine. Materials and Methods: Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student’s t test and Wilcoxon’s signed rank test. Results: Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE. Conclusion: As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T. Objective: To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine. Materials and Methods: Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student’s t test and Wilcoxon’s signed rank test. Results: Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE. Conclusion: As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T.

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      • 机电工程中智能化技术的应用探究

        黄益长(Yichang Huang),何黎斌(Libin He),任勇(Yong Ren) ACADEMIC FRONTIERS PUBLISHING GROUP(AFP) 2024 Journal of Engineering and Technology Management ( Vol.1 No.2

        随着科技的不断进步,智能化技术在建筑机电工程中的应用日益广泛,成为提升建筑功能和效率的关键因素,本文对智能化技术进行了定义,并回顾了其发展历程,强调了智能化技术在机电工程中的重要性,概述了智能化技术的主要类型及其在不同领域的应用情况。深入探讨了智能化技术在机电工程中的具体应用,包括智能化供电系统、暖通空调系统、消防系统和电梯系统。同时,分析了智能化技术应用所带来的优势,如节能减排和成本控制,以及面临的挑战,包括技术集成、数据安全和隐私保护问题,以及高昂的初期投资和维护成本。

      • KCI등재

        An Experimental and Numerical Investigation on the Twist Springback of Transformation Induced Plasticity 780 Steel Based on Different Hardening Models

        Yan-Min Xie,Ren-Yong Huang,Wei Tang,Bei-Bei Pan,Fei Zhang 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.4

        Investigation on twist springback is important to improve the accuracy of forming parts. In this paper, a double C rail made of transformation induced plasticity 780 (TRIP 780) steel is designed, and the stamping and twist springback are simulated with ABAQUS based on three different hardening models (including Ziegler, Johnson-Cook and combined hardening models). A new index for calculating the twist springback is proposed, which is based on the angle between two end section lines of the double C rail. The experimental results of twist springback are compared with the calculation results from three different hardening models. The calculation results based on combined hardening model are the closest to the experiment data. In order to compensate twist springback, a curved surface die is designed based on the geometric shape of the double C rail after twist springback. The stamping and twist springback are simulated based on the curved surface die and combined hardening model, and the twist springback is decreased obviously after compensation, which shows that the compensation of twist springback is effective.

      • Factors for Postoperative Gallstone Occurrence in Patients with Gastric Cancer: a Meta-analysis

        Chen, Xiang-Jun,Li, Nian,Huang, Ying-De,Ren, Shuang,Liu, Fang,Chen, Lian,Wang, Yong,Chen, Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        Objective: To evaluate risk factors for gallstones after gastrectomy. Methods: To identify documents published from 1990 to 2011 the Pubmed, Cochrane Library, Springer Link, CBM and WanFang databases were searched and a meta-analysis was performed with RevMan 5.2 software for odds ratios and 95%CIs. Results: Fifteen studies were selected for the meta-analysis. The pooled ORs [95%CIs] were 0.56 [0.43, 0.73], (P<0.0001) for digestive tract reconstruction, 0.80 [0.54, 1.17], (P=0.25) for pylorus preservation, 0.33[0.15, 0.75], (P=0.008) for resection scope of stomach, 0.33 [0.15, 0.75], (P=0.008) for lymphadenectomy, and 0.13 [0.05, 0.33], (P<0.0001) for vagotomy. Conclusions: Digestive tract physical reconstruction and vagus nerve preservation can reduce the morbidity of gallstones after gastrectomy. Total gastrectomy can add to the morbidity of galltones as does increasing the degree of lymph node dissection. There was no significant difference in gallstones with or without pylorus preservation.

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