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RISS 인기검색어
- 검색키워드
- 저자 : Razieh Choghakhori (검색결과 3 건)
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Amir Abbasnezhad,Ebrahim Falahi,Michael J. Gonzalez,Parivash Kavehi,Faezeh Fouladvand,Razieh Choghakhori 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.3
Dietary modification is an effective method for preventing and managing hypertension. Therefore, we conducted a systematic review and meta-analysis to assess the effects of different dietary approaches for comparing high- and low-carbohydrate diets on systolic and diastolic blood pressure (SBP and DBP, respectively) in patients with type 2 diabetes mellitus (T2DM). We carried out a comprehensive literature search using PubMed, the Cochrane Library, Web of Science, and Scopus without any language and time restrictions until April, 2019. We carried out a meta-analysis using both fixed and random effects models where appropriate and used the I² index to evaluate heterogeneity. We identified 16 eligible studies, with a total of 1,610 participants. The overall pooled net effect of different dietary approaches on SBP and DBP were −2.29 ㎜Hg [95% confidence interval (CI): −3.49 to −1.1] and −1.03 ㎜Hg (95% CI: −1.77 to −0.29), respectively, compared with high-carbohydrate diets. Indeed, diets high in monounsaturated fatty acids more effective in reducing both SBP and DBP than high-carbohydrate diets, whereas high-protein diets were not effective. Furthermore, we found that different dietary approaches, such as low-fat diets, did not reduce SBP or DBP to a greater extent than low-carbohydrate diets. Overall, the results of our meta-analysis show that diets high in monounsaturated fatty acids are more effective in reducing both SBP and DBP than diets high in carbohydrate, whereas other dietary approaches were not effective.
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Elham Eslampour,Farzad Ebrahimzadeh,Amir Abbasnezhad,Mohammad Zeinali Khosroshahi,Razieh Choghakhori,Omid Asbaghi 대한내분비학회 2019 Endocrinology and metabolism Vol.34 No.2
Background: Although previous studies have demonstrated that irisin plays an anti-inflammatory role in the body, conflicting results have been reported regarding the correlation between serum levels of irisin and C-reactive protein (CRP). The present metaanalysis was conducted to further investigate the correlation between irisin and CRP levels. Methods: We systematically searched PubMed, the Cochrane Library, Web of Science, Embase, SCOPUS, and Ovid to retrieve studies assessing the correlation between irisin and CRP levels. Meta-analyses were performed using a random-effects model, and the I2 index was used to evaluate heterogeneity. Results: Of the 428 studies that were initially found, 14 studies with 2,530 participants met the inclusion criteria for the meta-analysis. The pooled effect size was calculated as 0.052 (95% confidence interval, −0.047 to 0.152; P=0.302). Subgroup analyses identified s ignificant, positive, but weak correlations between CRP and irisin levels in cohort studies, studies conducted among healthy participants, studies in which the male-to-female ratio was less than 1, in overweight or obese subjects, and in studies with a samplesize of at least 100 participants. Conclusion: The present meta-analysis found no overall significant correlation between irisin and CRP levels, although a significant positive correlation was found in overweight or obese subjects. Well-designed studies are needed to verify the results of the present meta-analysis.
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Amir Abbasnezhad,Amin Hasanavand,Ebrahim Falahi,Sara Kashkooli,Omid Asbaghi,Razieh Choghakhori 한국식품영양과학회 2020 Preventive Nutrition and Food Science Vol.25 No.2
Results of previous studies regarding the effect of L-carnitine on lipid profiles in the patients with liver diseases are contradictory. This meta-analysis was performed to assess the effect of L-carnitine on serum levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG), and total cholesterol (TC) in overweight patients with liver diseases. A systematic search was carried out using the Web of Science, PubMed, Scopus, and Cochrane library databases to identify articles published before April 2019 investigating the effects of L-carnitine supplementation on patients with liver disease. There was no language or time limitation for the studies. A meta-analysis was carried out using both the random and fixed effects model where appropriate, and I2 index were used to evaluate heterogeneity. These results indicated that L-carnitine supplementation significantly reduces blood levels of TC and TG in patients with liver disease, whereas carnitine had no effect on the levels of HDL and LDL. The reducing effect of L-carnitine on both TC and TG was found following long-term carnitine supplementation (≥24 weeks), supplementation with doses less than or equal to 2,000 ㎎/d, and in patients with chronic hepatitis C. This meta-analysis indicates the beneficial effect of L-carnitine on TC and TG in overweight patients with liver disease, particularly patients with chronic hepatitis C, in both long-term and low doses.
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