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RISS 인기검색어
- 검색키워드
- 저자 : Ramesh Chander (검색결과 3 건)
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Irene Sarkar,Ramesh Chander 한국지질과학협의회 2002 Geosciences Journal Vol.6 No.3
The moderate magnitude Chamoli earthquake thatoccurred on March 29, 1999, in the Garhwal Higher Himalayaproduced, among many other observable effects, changes in flowof several artisan springs. Qualitative observations of significantchanges in the flow of ten springs located in regions of higherintensity show a strong spatial correlation with our preliminaryestimates of perturbing pore pressure field induced in the watersaturated shallow rocks of the region by the earthquake in its coseis-mic phase. The results are significant for it is the first successfulattempt in the Himalayan region to investigate the response patternof the local groundwater flow system to perturbations induced tothe ambient tectonic stress regime by a major earthquake.
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Genetic Structure and Differentiation of Three Indian Goat Breeds
Dixit, S.P.,Verma, N.K.,Aggarwal, R.A.K.,Kumar, Sandeep,Chander, Ramesh,Vyas, M.K.,Singh, K.P. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.9
Gene flow, genetic structure and differentiation of Kutchi, Mehsana and Sirohi breeds of goat from North-Western India were evaluated based on 25 microsatellite markers so as to support breed conservation and improvement decisions. The microsatellite genotyping was carried out using an automated DNA sequencer. The gene diversity across the studied loci for the Kutchi breed varied from 0.57 (ILST 065) to 0.93 (OarFCB 304, OMHC 1, ILSTS 058) with an overall mean of 0.79${\pm}$0.02. The corresponding values for Mehsana and Sirohi breeds were 0.16 (ILST 008) to 0.93 (OMHC 1, ILSTS 058) with an average of 0.76${\pm}$0.04, and 0.50 (ILSTS 029) to 0.94 (ILSTS 058) with an average of 0.78${\pm}$0.02, respectively. The Mehsana breed had lowest gene diversity among the 3 breeds studied. All the populations showed an overall significant heterozygote deficit ($F_{is}$). The Fis values were 0.26, 0.14 and 0.36 for Kutchi, Mehsana and Sirohi goat breeds, respectively. Kutchi and Mehsana were more differentiated (16%) followed by Mehsana and Sirohi (13%).The measures of standard genetic distance between pairs of breeds indicated that the lowest genetic distance was between Kutchi and Sirohi breeds (0.73) and the largest genetic distance was between Mehsana and Kutchi (1.0) followed by Sirohi and Mehsana (0.75) breeds. Mehsana and Kutchi are distinct breeds and this was revealed by the estimated genetic distance between them. All measures of genetic variation revealed substantial genetic variation in each of the populations studied, thereby showing good scope for their further improvement.
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Anu Chandra,Abbas Ali Mahdi,Raj Kumar Singh,Farzana Mahdi,Ramesh Chander 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.3
In the present investigation we report the protective potential of some herbal hypoglycemic agents on antioxidant status and levels of metal ions in streptozotocin-induced diabetic rats. Furthermore, in vitro antioxidant activity of the herbs was also evaluated. Induction of diabetes mellitus in rats caused an increase in blood lipid peroxide levels that was associated with the reduced activity of red blood cell (RBC) antioxidant enzymes—namely, superoxide dismutase, catalase, glutathione reductase, and glutathione peroxidase—along with depletion of plasma reduced glutathione (GSH) and copper, zinc, iron, magnesium, and selenium levels. Oral treatment of diabetic rats with Allium sativum, Azadirachta indica, Momordica charantia, and Ocimum sanctum extracts (500 mg/kg of body weight) not only lowered the blood glucose level but also inhibited the formation of lipid peroxides, reactivated the antioxidant enzymes, and restored levels of GSH and metals in the above-mentioned model. The herbal extracts (50–500 μg) inhibited the generation of superoxide anions (O2.) in both enzymatic and nonenzymatic in vitro systems. These preparations also inhibited the ferrous-sodium ascorbate-induced formation of lipid peroxides in RBCs. The in vivo and in vitro protective effects of the above-mentioned herbal drugs were also compared with that of glibenclamide. On the basis of our results, we conclude that the above-mentioned herbal plants not only possess hypoglycemic properties, but they also decrease oxidative load in diabetes mellitus. Therefore, we propose that long-term use of such agents might help in the prevention of diabetes-associated complications. However, the extrapolation of these results to humans needs further in-depth study.
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