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1
Study on the Application of 17 Wild Plant Species in Greening the Abandoned Quarry

Cai qiong Wu,Shanghai Lai,Tao Xu,Jiangli Lei,Yiyan Xu 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-
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2
Nitrate reduction and its effects on trichloroethylene degradation by granular iron

Lu, Qiong,Jeen, Sung-Wook,Gui, Lai,Gillham, Robert W. Pergamon Press 2017 Water research Vol.112 No.-
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Abstract Laboratory column experiments and reactive transport modeling were performed to evaluate the reduction of nitrate and its effects on trichloroethylene (TCE) degradation by granular iron. In addition to determining degradation kinetics of TCE in the presence of nitrate, the columns used in this study were equipped with electrodes which allowed for in situ measurements of corrosion potentials of the iron material. Together with Raman spectroscopic measurements the mechanisms of decline in iron reactivity were examined. The experimental results showed that the presence of nitrate resulted in an increase in corrosion potential and the formation of thermodynamically stable passive films on the iron surface which impaired iron reactivity. The extent of the decline in iron reactivity was proportional to the nitrate concentration. Consequently, significant decreases in TCE and nitrate degradation rates and migration of degradation profiles for both compounds occurred. Furthermore, the TCE degradation kinetics deviated from the pseudo-first-order model. The results of reactive transport modeling, which related the amount of a passivating iron oxide, hematite (α-Fe2O3), to the reactivity of iron, were generally consistent with the patterns of migration of TCE and nitrate profiles observed in the column experiments. More encouragingly, the simulations successfully demonstrated the differences in performances of three columns without changing model parameters other than concentrations of nitrate in the influent. This study could be valuable in the design of iron permeable reactive barriers (PRBs) or in the development of effective maintenance procedures for PRBs treating TCE-contaminated groundwater with elevated nitrate concentrations. Highlights <UL> <LI> Nitrate reduction impaired iron reactivity for trichloroethylene degradation. </LI> <LI> Nitrate reduction resulted in formation of passive films on iron surfaces. </LI> <LI> The iron reactivity decline was proportional to the nitrate concentration. </LI> <LI> Modeling can be valuable in designing of permeable reactive barriers. </LI> </UL> Graphical abstract [DISPLAY OMISSION]
3
Cardioprotective effect of ginsenoside Rb1 via regulating metabolomics profiling and AMP-activated protein kinase-dependent mitophagy

Jingui Hu,Ling Zhang,Fei Fu,Qiong Lai,Lu Zhang,Tao Liu,Boyang Yu,Junping Kou,Fang Li 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.2
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  DBpia
  
  ScienceON
Background: Ginsenoside Rb1, a bioactive component isolated from the Panax ginseng, acts as a remedy to prevent myocardial injury. However, it is obscure whether the cardioprotective functions of Rb1 are related to the regulation of endogenous metabolites, and its potential molecular mechanism still needs further clarification, especially from a comprehensive metabolomics profiling perspective. Methods: The mice model of acute myocardial ischemia (AMI) and oxygen glucose deprivation (OGD)-induced cardiomyocytes injury were applied to explore the protective effect and mechanism of Rb1. Meanwhile, the comprehensive metabolomics profiling was conducted by high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (HPLC-Q/TOF-MS) and a tandem liquid chromatography and mass spectrometry (LC-MS). Results: Rb1 treatment profoundly reduced the infarct size and attenuated myocardial injury. The metabolic network map of 65 differential endogenous metabolites was constructed and provided a new inspiration for the treatment of AMI by Rb1, which was mainly associated with mitophagy. In vivo and in vitro experiments, Rb1 was found to improve mitochondrial morphology, mitochondrial function and promote mitophagy. Interestingly, the mitophagy inhibitor partly attenuated the cardioprotective effect of Rb1. Additionally, Rb1 markedly facilitated the phosphorylation of AMP-activated protein kinase a (AMPKa), and AMPK inhibition partially weakened the role of Rb1 in promoting mitophagy. Conclusions: Ginsenoside Rb1 protects acute myocardial ischemia injury through promoting mitophagy via AMPKa phosphorylation, which might lay the foundation for the further application of Rb1 in cardiovascular diseases.