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RISS 인기검색어
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- 저자 : Qingjiang Sun (검색결과 3 건)
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Fasting Blood Glucose, Cholesterol, and Risk of Primary Liver Cancer: The Kailuan Study
Xiangming Ma,Haozhe Cui,Miaomiao Sun,Qian Liu,Xining Liu,Guangjian Li,Yaochen Wei,Qingjiang Fu,Siqing Liu,Liying Cao 대한암학회 2021 Cancer Research and Treatment Vol.53 No.4
Purpose The influence of fasting blood glucose (FBG) and cholesterolemia primary liver cancer (PLC) in China was analyzed via a large prospective cohort study based on a community population, and the combined effects between them were investigated. Materials and Methods Overall, 98,936 staff from the Kailuan Group who participated in and finished physical examinations bet-ween 2006 and 2007 were included in the cohort study. Their medical information was collected and they were followed up after examination. The correlations of serum FBG or total cholesterol (TC) with PLC were analyzed. Then, we categorized all staff into four groups: normal FBG/non-hypocholesterolemia, normal FBG/hypocholesterolemia, elevated FBG/non-hypocholesterolemia, elevated FBG/hypocholesterolemia, and normal FBG/non-hypocholesterolemia was used as a control group. The combined effects of elevated FBG and hypocholesterolemia with PLC were analyzed using the Age-scale Cox proportional hazard regression model. Results During 1,134,843.68 person-years follow-up, a total of 388 PLC cases occurred. We found the elevated FBG and hypocholesterolemia increase the risk for PLC, respectively. Compared with the non-hypocholesterolemia/normal FBG group, the risk of PLC was significantly increased in the non-hypocholesterolemia/elevated FBG group (hazard artio [HR], 1.19; 95% confidence interval [CI], 0.88 to 1.62) and hypocholesterolemia/normal FBG group (HR, 1.53; 95% CI, 1.19 to 1.97), and in the hypocholesterolemia/elevated FBG group (HR, 3.16; 95% CI, 2.13 to 4.69). And, a significant interaction effect was found of FBG and TC on PLC. All results were independent from the influence of liver disease. Conclusion Elevated serum FBG and hypocholesterolemia are risk factors for PLC, especially when combined. Thus, for the prevention and treatment of PLC, serum FBG and TC levels should be investigated.
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Bin Xu,Jingwen Xue,Jun Huang,Haojun Jin,Peng Shen,Qingjiang Sun 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.15 No.01
The doped quantum dots (QDs) that feature dual emission in one nanocrystal and long fluorescence lifetime have gained great interest in biosensing and bioimaging applications. In this work, we report the synthesis and functionalization of copper ion-doped indium phosphate (Cu:InP) QDs that exhibit simultaneous green InP emission and red Cu2+ emission. The oil-soluble QDs were synthesized by adsorbing Cu2+ onto InP core, followed by growing zinc selenide (ZnSe) shell via the successive ion layer adsorption reaction. During the synthesis, fluorescence ratiometry (and resultant multiple fluorescence colors) can be generated by changing either the dopant amount or the shell-growth time, but they act in a different manner: increasing the Cu2+ amount results in quenched InP emission and oppositely improved Cu2+ emission; the increase of shell-growth time leads to continuously improved Cu2+ emission relative to constant InP emission. Further, functionalization of the oil-soluble Cu:InP QDs with dihydrolipoic acid-polyethylene glycol (DHLA-PEG) via ligand exchange produces the water-soluble and biocompatible dual-emission QDs. The PEGylated Cu:InP QDs present desirable charge neutrality and excellent thermal stability and photostability, thereby holding high potential in a diversity of biomedical applications.
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Effect of Annealing on Lattice Strain and Near-Band-Edge Emission of ZnO Nanorods
Musbah Babikier,Jinzhong Wang,Dunbo Wang,Qian Li,Jianming Sun,Yuan Yan,Wenqi Wang,Qingjiang Yu,Shujie Jiao,Shiyong Gao,Hongtao Li 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.4
The effect of air and oxygen annealing on the structural and the optical properties of hydrothermally synthesized ZnO nanorods was investigated. After hydrothermal synthesis, the resulting ZnO nanorods were annealed in air and under an oxygen atmosphere at 370°C for 1 h. X-ray diffraction results revealed that the oxygen-annealed nanorods possessed high crystallinity with a hexagonal-wurtzite crystal structure in the (002) plane. Evaluation of strain showed a tensile lattice strain of 0.426% resulting from oxygen annealing. The photoluminescence measurements showed that the relative intensity ratio of the near-band-edge emission (NBE) to the green emission (INBE/IGE) increased from ~2.6 for the as-grown ZnO nanorods to ~68.7 when the nanorods were annealed under oxygen. After annealing, a red shift of ~30 and ~44 meV in the NBE was observed for the nanorods that were annealed in air and under oxygen, respectively. This shift is attributed to the interaction between the neutral acceptors and the adsorbed oxygen atoms.
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