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Endovascular Closure Resolves Trimethylaminuria Caused by Congenital Portosystemic Shunts
Ponce-Dorrego, Mar?a Dolores,Garzon-Moll, Gonzalo The Korean Society of Pediatric Gastroenterology 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.6
This study aimed to report three new cases of an association between two rare conditions, congenital portosystemic shunts (CPSS) and trimethylaminuria (TMAU), and the efficacy of endovascular closure of the CPSS for resolving TMAU. Between November 2014 and April 2017, 15 patients with CPSS were enrolled in this prospective study to assess the efficacy of percutaneous endovascular shunt closure. Three patients presented with clinical symptoms of TMAU that were confirmed by urine analysis of trimethylamine (TMA) and TMA n-oxide. One year after endovascular closure of the congenital portosystemic shunt, the same parameters were evaluated were obtained and the values were compared to the pretreatment values. The results indicated the disappearance of clinical symptoms of TMAU and normalization of the urine test parameters in two patients and no changes in one patient, who developed new portosystemic communications.
Ponce-Garcia, Gustavo,Villanueva-Segura, Olga K.,Garza-Elizondo, Karina,Villegas-Ramirez, Heriberto M.,Fernandez-Salas, Ildefonso,Rodriguez-Sanchez, Iram P.,Dzul-Manzanilla, Felipe,Flores-Suarez, Adri The Korea Society for Parasitology and Tropical Me 2022 The Korean Journal of Parasitology Vol.60 No.3
The head louse Pediculus humanus capitis (De Geer) is a hematophagous ectoparasite that inhabits the human scalp. The infestations are asymptomatic; however, skin irritation from scratching occasionally may cause secondary bacterial infections. The present study determined the presence and frequency of the knockdown resistance (kdr) mutation T929I in 245 head lice collected from Mexico, Peru, and Canada. Head lice were collected manually using a comb in the private head lice control clinic. Allele mutation at T9291 was present in 100% of the total sampled populations (245 lice) examined. In addition, 4.89% of the lice were homozygous susceptible, whereas 6.93% heterozygous and 88.16% homozygous were resistant, respectively. This represents the second report in Mexico and Quebec and fist in Lima.
Endovascular Closure Resolves Trimethylaminuria Caused by Congenital Portosystemic Shunts
María Dolores Ponce-Dorrego,Gonzalo Garzón-Moll 대한소아소화기영양학회 2019 Pediatric gastroenterology, hepatology & nutrition Vol.22 No.6
This study aimed to report three new cases of an association between two rare conditions, congenital portosystemic shunts (CPSS) and trimethylaminuria (TMAU), and the efficacy of endovascular closure of the CPSS for resolving TMAU. Between November 2014 and April 2017, 15 patients with CPSS were enrolled in this prospective study to assess the efficacy of percutaneous endovascular shunt closure. Three patients presented with clinical symptoms of TMAU that were confirmed by urine analysis of trimethylamine (TMA) and TMA n-oxide. One year after endovascular closure of the congenital portosystemic shunt, the same parameters were evaluated were obtained and the values were compared to the pretreatment values. The results indicated the disappearance of clinical symptoms of TMAU and normalization of the urine test parameters in two patients and no changes in one patient, who developed new portosystemic communications.
Endovascular Treatment of Congenital Portosystemic Shunt: A Single-Center Prospective Study
María-Dolores Ponce-Dorrego,Teresa Hernández-Cabrero,Gonzalo Garzón-Moll 대한소아소화기영양학회 2022 Pediatric gastroenterology, hepatology & nutrition Vol.25 No.2
Purpose: To design a prospective study on endovascular closure of congenital portosystemic shunts. The primary endpoint was to assess the safety of endovascular closure. The secondary endpoint was to evaluate the clinical, analytical and imaging outcomes of treatment. Methods: Fifteen patients (age range: 2 days to 21 years; 10 male) were referred to our center due to congenital portosystemic shunts. The following data were collected prior to treatment: age, sex, medical history, clinical and analytical data, urine trimethylaminuria, abdominal-US, and body-CT. The following data were collected at the time of intervention: anatomical and hemodynamic characteristics of the shunts, device used, and closure success. The following data were collected at various post-intervention time points: during hospital stay (to confirm shunt closure and detect complications) and at one year after (for clinical, analytical, and imaging purposes). Results: The treatment was successful in 12 participants, migration of the device was observed in two, while acute splanchnic thrombosis was observed in one. Off-label devices were used in attempting to close the side-to-side shunts, and success was achieved using Amplatzer™ Ductus-Occluder and Amplatzer™ Muscular-Vascular-Septal-Defect-Occluder. The main changes were: increased prothrombin activity (p=0.043); decreased AST, ALT, GGT, and bilirubin (p=0.007, p=0.056, p=0.036, p=0.013); thrombocytopenia resolution (p=0.131); expansion of portal veins (p=0.005); normalization of Doppler portal flow (100%); regression of liver nodules (p=0.001); ammonia normalization (p=0.003); and disappearance of trimethylaminuria (p=0.285). Conclusion: Endovascular closure is effective. Our results support the indication of endovascular closure for side-to-side shunts and for cases of congenital absence of portal vein.
Do Remittances Crowd Out the Government’s Redistributive Policy?
IKUHO KOCHI;RAUL ALBERTO PONCE RODRIGUEZ 경제연구소 2010 Journal of Economic Development Vol.35 No.4
In this paper, we develop a political economy model with a voting equilibrium to analyze the impact of remittances in the government’s redistributive policy. Remittances affect the distribution of income and the households’ demand for public redistribution. In this paper we consider the impact of remittances on two types of redistributive programs: a universal and a targeted transfer program. For an economy with targeted public transfers, we identify conditions in which an increase in remittances crowds out the social transfers of the government. If the redistributive program is universal then an increase in remittances actually increases the size of the government’s transfers.
Luz M. Ramos-Ponce,Mireille Vega,Edith Colunga-Urbina,Georgina C. Sandoval-Fabián,Nagamani Balagurusamy,Juan Carlos Contreras-Esquivel,Francisco J. Rodriguez-Gonzalez 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.3
A colorimetric method for quantitative measurement of free amino groups of water soluble chitin derivatives is described. The method utilizes genipin as a natural and specific reagent for determining the concentration of free amino groups in samples of water soluble chitin derivatives. The blue color adduct (complex) formed during genipin reaction with free amino groups was measured at about 589 nm and Beer-Lambert’s law obeyed over the concentration range of 50 to 300 mg/L. Parameters of analytical conditions were considered and kept constant during the experimental procedure. Highly acetylated water soluble chitin derivatives can be differentiated from water soluble chitosan using this genipin method. The colorimetric method with genipin was proved to be a rapid and efficient technique to determine the free amino groups in water soluble chitin derivatives. This method can also be applied for the detection of the enzymatic activity of chitindeacetylase.
Are the long–short term memory and convolution neural networks really based on biological systems?
David Balderas Silva,Pedro Ponce Cruz,Arturo Molina Gutierrez 한국통신학회 2018 ICT Express Vol.4 No.2
In general, it is not a simple task to predict sequences or classify images, and it is even more problematic when both are combined. Nevertheless, biological systems can easily predict sequences and are good at image recognition. For these reasons Long–Short Term Memory and Convolutional Neural Networks were created and were based on the memory and visual systems. These algorithms have shown great properties and shown certain resemblance, yet they are still not the same as their biological counterpart. This article reviews the biological bases and compares them.
DO REMITTANCES CROWD OUT THE GOVERNMENT’S REDISTRIBUTIVE POLICY?
IKUHO KOCHI,RAÚL ALBERTO PONCE RODRÍGUEZ 중앙대학교 경제연구소 2010 Journal of Economic Development Vol.35 No.4
In this paper, we develop a political economy model with a voting equilibrium to analyze the impact of remittances in the government’s redistributive policy. Remittances affect the distribution of income and the households’ demand for public redistribution. In this paper we consider the impact of remittances on two types of redistributive programs: a universal and a targeted transfer program. For an economy with targeted public transfers, we identify conditions in which an increase in remittances crowds out the social transfers of the government. If the redistributive program is universal then an increase in remittances actually increases the size of the government’s transfers.