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RISS 인기검색어
- 검색키워드
- 저자 : Peter Van Dael (검색결과 2 건)
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Peter Van Dael 한국영양학회 2021 Nutrition Research and Practice Vol.15 No.2
Long-chain (LC) n-3 polyunsaturated fatty acids (n-3 PUFAs), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), are nutrients involved in many metabolic and physiological processes, and are referred to as n-3 LCPUFA. They have been extensively studied for their effects in human nutrition and health. This paper provides an overview on metabolism, sources, dietary intake, and status of n-3 LCPUFA. A summary of the dietary recommendations for n-3 LCPUFAs for different age groups as well as specific physiological conditions is provided. Evidence for n-3 LCPUFA in cardiovascular diseases, including new studies, is reviewed. Expert recommendations generally support a beneficial effect of n-3 LCPUFA on cardiovascular health and recommend a daily intake of 500 mg as DHA and EPA, or 1–2 servings of fish per week. The role of n-3 LCPUFA on brain health, in particular neurodegenerative disorders and depression, is reviewed. The evidence for beneficial effects of n-3 LCPUFA on neurodegenerative disorders is non-conclusive despite mechanistic support and observational data. Hence, no definite n-3 LCPUFA expert recommendations are made. Data for the beneficial effect of n-3 LCPUFA on depression are generally compelling. Expert recommendations have been established: 200–300 mg/day for depression; up to 1–2 g/day for major depressive disorder. Recent studies support a beneficial role of n-3 LCPUFAs in reducing the risk for premature birth, with a daily intake of 600–800 mg of DHA during pregnancy. Finally, international experts recently reviewed the scientific evidence on DHA and arachidonic acid (ARA) in infant nutrition and concluded that the totality of data support that infant and follow-on formulas should provide both DHA and ARA at levels similar to those in breast milk. In conclusion, the available scientific data support that dietary recommendations for n-3 LCPUFA should be established for the general population and for subjects with specific physiological conditions.
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Recent Studies on the Health Benefits of Omega-3 Polyunsaturated Fatty Acids
James D. Richards,Taichi Inui,Peter Van Dael 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Long-chain omega-3 polyunsaturated fatty acids (n-3 LCPUFAs), in particular docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), are nutrients involved in several metabolic and physiological processes. They have been extensively studied for their effects in human nutrition and health. This talk will provide a brief overview on metabolism, sources, dietary intake, and global intake and status of n-3 LCPUFA. Recommendations from expert groups and scientific authorities for n-3 LCPUFA intakes for different age groups as well as specific physiological conditions will be discussed. Evidence for n-3 LCPUFA in supporting a wide variety of health benefits, in several different populations/life stages, will be reviewed. These benefits include positive effects with respect to heart health; neurodevelopment in infants (when combined with arachidonic acid in appropriate levels and ratios); cognition, and depression/mood including in older adults; support of immune function; as well as the most recent data on the important role these fatty acids play in reducing incidence of early preterm birth. The totality of available data support multiple roles of n-3 LCPUFAs on a diversity of positive health effects across the entirety of the lifespan.
ScienceON
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