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      • SCOPUSKCI등재

        Characterization of mandibular molar root and canal morphology using cone beam computed tomography and its variability in Belgian and Chilean population samples

        Torres, Andres,Jacobs, Reinhilde,Lambrechts, Paul,Brizuela, Claudia,Cabrera, Carolina,Concha, Guillermo,Pedemonte, Maria Eugenia Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.2

        Purpose: This study used cone-beam computed tomography (CBCT) to characterize mandibular molar root and canal morphology and its variability in Belgian and Chilean population samples. Materials and Methods: We analyzed the CBCT images of 515 mandibular molars (257 from Belgium and 258 from Chile). Molars meeting the inclusion criteria were analyzed to determine (1) the number of roots; (2) the root canal configuration; (3) the presence of a curved canal in the cross-sectional image of the distal root in the mandibular first molar and (4) the presence of a C-shaped canal in the second mandibular molar. A descriptive analysis was performed. The association between national origin and the presence of a curved or C-shaped canal was evaluated using the chi-squared test. Results: The most common configurations in the mesial root of both molars were type V and type III. In the distal root, type I canal configuration was the most common. Curvature in the cross-sectional image was found in 25% of the distal canals of the mandibular first molars in the Belgian population, compared to 11% in the Chilean population. The prevalence of C-shaped canals was 10% or less in both populations. Conclusion: In cases of unclear or complex root and canal morphology in the mandibular molars, CBCT imaging might assist endodontic specialists in making an accurate diagnosis and in treatment planning.

      • SCISCIESCOPUS

        Efficacy of a high quality O<sub>1</sub>/Campos foot-and-mouth disease vaccine upon challenge with a heterologous Korean O Mya98 lineage virus in pigs

        Galdo Novo, S.,Malirat, V.,Maradei, E.D.,Pedemonte, A.R.,Espinoza, A.M.,Smitsaart, E.,Lee, K.N.,Park, J.H.,Bergmann, I.E. Elsevier 2018 Vaccine Vol.36 No.12

        <P><B>Abstract</B></P> <P>In 2010 serotype O foot-and-mouth disease virus of the Mya98 lineage/SEA topotype spread into most East Asian countries. During 2010–2011 it was responsible for major outbreaks in the Republic of Korea where a monovalent O/Manisa vaccine (belonging to the ME-SA topotype) was applied to help control the outbreaks. Subsequently, all susceptible animals were vaccinated every 6 months with a vaccine containing the O/Manisa antigen. Despite vaccination, the disease re-occurred in 2014 and afterwards almost annually. This study focuses on the <I>in vivo</I> efficacy in pigs of a high quality monovalent commercial O<SUB>1</SUB>/Campos vaccine against heterologous challenge with a representative 2015 isolate from the Jincheon Province of the Republic of Korea. Initially, viral characterizations and r<SUB>1</SUB> determinations were performed on six viruses recovered in that region during 2014–2015, centering on their relationship with the well characterized and widely available O<SUB>1</SUB>/Campos vaccine strain. Genetic and antigenic analysis indicated a close similarity among 2014–2015 Korean isolates and with the previous 2010 virus, with distinct differences with the O<SUB>1</SUB>/Campos strain. Virus neutralisation tests using O<SUB>1</SUB>/Campos cattle and pig post vaccination sera and recent Korean outbreak viruses predicted acceptable cross-protection after a single vaccination, as indicated by r<SUB>1</SUB> values, and in pigs, by expectancy of protection. In agreement with the <I>in vitro</I> estimates, <I>in vivo</I> challenge with a selected field isolate indicated that O<SUB>1</SUB>/Campos primo vaccinated pigs were protected, resulting in a PD50 value of nearly 10. The results indicated that good quality oil vaccines containing the O<SUB>1</SUB>/Campos strain can successfully be used against isolates belonging to the O Mya98/SEA topotype.</P>

      • KCI등재

        Characterization of mandibular molar root and canal morphology using cone beam computed tomography and its variability in Belgian and Chilean population samples

        Andres Torres,Reinhilde Jacobs,Paul Lambrechts,Claudia Brizuela,Carolina Cabrera,Guillermo Concha,María Eugenia Pedemonte 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.2

        Purpose: This study used cone-beam computed tomography (CBCT) to characterize mandibular molar root and canal morphology and its variability in Belgian and Chilean population samples. Materials and Methods: We analyzed the CBCT images of 515 mandibular molars (257 from Belgium and 258 from Chile). Molars meeting the inclusion criteria were analyzed to determine (1) the number of roots; (2) the root canal configuration; (3) the presence of a curved canal in the cross-sectional image of the distal root in the mandibular first molar and (4) the presence of a C-shaped canal in the second mandibular molar. A descriptive analysis was performed. The association between national origin and the presence of a curved or C-shaped canal was evaluated using the chi-squared test. Results: The most common configurations in the mesial root of both molars were type V and type III. In the distal root, type I canal configuration was the most common. Curvature in the cross-sectional image was found in 25% of the distal canals of the mandibular first molars in the Belgian population, compared to 11% in the Chilean population. The prevalence of C-shaped canals was 10% or less in both populations. Conclusion: In cases of unclear or complex root and canal morphology in the mandibular molars, CBCT imaging might assist endodontic specialists in making an accurate diagnosis and in treatment planning.

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