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Designing Reliability Improvement Model Using Design Structure Matrix
Karbasian, Mehdi,Kazemi, Sayed Mohammad,Khayambashi, Bijan,Nilipour, Sayed Akbar Korean Institute of Industrial Engineers 2017 Industrial Engineeering & Management Systems Vol.16 No.4
As an inherent characteristic of any product or system, reliability is one of the parameters of design, construction and operation to be considered and controlled as an important criterion during relevant processes. The need to ensure the continuous and proper functioning of a product has led designers to pay special attention to increasing reliability. Therefore by coordinating all design experts and support groups throughout the implementation of product life cycle, the product development life cycle period can be reduced and value-creation of products increased. As a result, the existence of a comprehensive model is of vital importance. In this study, all industrial engineering techniques effective in improving reliability are first identified and then prioritized in all phases of the product life cycle using multi-criteria decision making method. Finally, using design structure matrix, priority and posteriority of all techniques is determined in each phase and a systematic model is provided to improve equipment reliability.
Expression of Neuronal Markers, NFP and GFAP, in Malignant Astrocytoma
Hashemi, Forough,Naderian, Majid,Kadivar, Maryam,Nilipour, Yalda,Gheytanchi, Elmira Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Background: Immunohistochemical markers are considered as important factors in diagnosis of malignant astrocytomas. The aim of the current study was to investigate the frequency of the immunohistochemical markers neurofilament protein (NFP) and glial fibrillary acidic protein (GFAP) in malignant astrocytoma tumors in Firoozgar and Rasool-Akram hospitals from 2005 to 2010. Materials and Methods: In this cross-sectional study, immunohistochemical analysis of NFP and GFAP was performed on 79 tissue samples of patients with the diagnosis of anaplastic and glioblastoma multiform (GBM) astrocytomas. Results: The obtained results demonstrated that all patients were positive for GFAP and only 3.8% were positive for NFP. There was no significant association between these markers and clinical, demographic, and prognostic features of patients (p>0.05). Conclusions: NFP was expressed only in GBMs and not in anaplastic astrocytomas. It would be crucial to confirm the present findings in a larger number of tumors, especially in high grade gliomas.
Behnam, Mahdiyeh,Jin-Hong, Shin,Kim, Dae-Seong,Basiri, Keivan,Nilipour, Yalda,Sedghi, Maryam Medknow PublicationsMedia Pvt Ltd 2014 Journal of research in medical sciences Vol.19 No.8
<P>Hereditary inclusion body myopathy (hIBM) is an adult-onset hereditary myopathy, usually with distal onset and quadriceps sparing. This myopathy is autosomal recessive and associated to UPD-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) gene mutations. In this study, we report a novel GNE homozygous point mutation c.1834T>G that results in amino acid substitution of cysteine 612 to glutamine in an Iranian patient. This mutation is located in exon 10 within the kinase domain of the protein.</P>
Designing Reliability Improvement Model Using Design Structure Matrix
Mehdi Karbasian,Sayed Mohammad Kazemi,Bijan Khayambashi,Sayed Akbar Nilipour 대한산업공학회 2017 Industrial Engineeering & Management Systems Vol.16 No.4
As an inherent characteristic of any product or system, reliability is one of the parameters of design, construction and operation to be considered and controlled as an important criterion during relevant processes. The need to ensure the continuous and proper functioning of a product has led designers to pay special attention to increasing reliability. Therefore by coordinating all design experts and support groups throughout the implementation of product life cycle, the product development life cycle period can be reduced and value-creation of products increased. As a result, the existence of a comprehensive model is of vital importance. In this study, all industrial engineering techniques effective in improving reliability are first identified and then prioritized in all phases of the product life cycle using multicriteria decision making method. Finally, using design structure matrix, priority and posteriority of all techniques is determined in each phase and a systematic model is provided to improve equipment reliability.