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RISS 인기검색어
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- 저자 : Niekamp, R. (검색결과 5 건)
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Formulation, solution and CTL software for coupled thermomechanics systems
Niekamp, R.,Ibrahimbegovic, A.,Matthies, H.G. Techno-Press 2014 Coupled systems mechanics Vol.3 No.1
In this work, we present the theoretical formulation, operator split solution procedure and partitioned software development for the coupled thermomechanical systems. We consider the general case with nonlinear evolution for each sub-system (either mechanical or thermal) with dedicated time integration scheme for each sub-system. We provide the condition that guarantees the stability of such an operator split solution procedure for fully nonlinear evolution of coupled thermomechanical system. We show that the proposed solution procedure can accommodate different evolution time-scale for different sub-systems, and allow for different time steps for the corresponding integration scheme. We also show that such an approach is perfectly suitable for parallel computations. Several numerical simulations are presented in order to illustrate very satisfying performance of the proposed solution procedure and confirm the theoretical speed-up of parallel computations, which follow from the adequate choice of the time step for each sub-problem. This work confirms that one can make the most appropriate selection of the time step with respect to the characteristic time-scale, carry out the separate computations for each sub-system, and then enforce the coupling to preserve the stability of the operator split computations. The software development strategy of direct linking the (existing) codes for each sub-system via Component Template Library (CTL) is shown to be perfectly suitable for the proposed approach.
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Microbial Metabolite Dysbiosis and Colorectal Cancer
Niekamp Patrick,Kim Chang H. 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2
The global burden of colorectal cancer (CRC) is expected to continuously increase. Through research performed in the past decades, the effects of various environmental factors on CRC development have been well identified. Diet, the gut microbiota and their metabolites are key environmental factors that profoundly affect CRC development. Major microbial metabolites with a relevance for CRC prevention and pathogenesis include dietary fiber-derived short-chain fatty acids, bile acid derivatives, indole metabolites, polyamines, trimethylamine-N-oxide, formate, and hydrogen sulfide. These metabolites regulate various cell types in the intestine, leading to an altered intestinal barrier, immunity, chronic inflammation, and tumorigenesis. The physical, chemical, and metabolic properties of these metabolites along with their distinct functions to trigger host receptors appear to largely determine their effects in regulating CRC development. In this review, we will discuss the current advances in our understanding of the major CRC-regulating microbial metabolites, focusing on their production and interactive effects on immune responses and tumorigenesis in the colon.
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Ibrahimbegovic, Adnan,Kassiotis, Christophe,Niekamp, Rainer Techno-Press 2016 Coupled systems mechanics Vol.5 No.2
An efficient and general numerical strategy for fluid-structure interaction problems is presented where either the fluid or the structure part are represented by nonlinear models. This partitioned strategy is implemented under the form of code coupling that allows to (re)-use previous made developments in a more general multi-physics context. This strategy and its numerical implementation is verified on classical fluid-structure interaction benchmarks, and then applied to the impact of tsunamis waves on submerged structures.
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Development of the Australian Maritime College PC Based Machinery Space Simulator
Laurie Goldsworthy,Byung-gun Jung,Peter Niekamp,Stan Earl 한국해양대학교 해사산업연구소 2003 海事産業硏究所論文集 Vol.13 No.-
The development of a PC based machinery space simulator for training and research is described. Development goals targeted the usefulness of the system for both training and R&D work. These included a distributed client/server architecture for 1-1 or 1-many client simulation operation, complete separation of visual elements from the controlling routines and the ability to work on the mathematical model (fully compileable source) independent of the controller and visual systems. A graphical interface has been developed and the mathematical model has been updated. NOx emissions and the effect of NOx control measures are simulated. Variable fuel combustion quality can be simulated. The use of the PC based simulator for training of sea going engineers and its relevance to STCW-95 is discussed. The use of the PC based simulator for undergraduate and graduate project work is also discussed.
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기관 구역 시뮬레이터 교육의 효율적 수행 방안에 관한 소고
정병건(Byung-Gun Jung),Peter Niekamp, 박재식(Jae-Shik Park) 한국해양대학교 해사산업연구소 2002 海事産業硏究所論文集 Vol.12 No.-
This paper suggests a method to perform effective education and training for pc-based machinery space simulator. The method includes sequence, procedure, exercise and evaluation. The sequence and procedure present explanation for the machinery and guide trainee to the competent level. The exercise enhances understanding for efficient engine management and enable user to perform research for the machinery. The evaluation shows exercise results and feedbacks instructor how to guide the under-performed trainee.
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