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Can we predict preterm birth by analyzing the vaginal microbiome using machine learning techniques?
( Sunwha Park ),( Jeongsup Moon ),( Nayeon Kang ),( Young Min Hur ),( Young-ah You ),( Soo Min Kim ),( Gain Lee ),( Yun Ji Jung ),( Young-han Kim ),( Taesung Park ),( Young Ju Kim ) 대한산부인과학회 2021 대한산부인과학회 학술대회 Vol.107 No.-
경피적 관상동맥중재술 후 재협착 예방에 대한 한약의 효과 : 무작위배정 대조군 임상연구에 대한 체계적 문헌고찰 및 메타분석
허나연,안수빈,김홍준,장인수,Nayeon Hur,Subin Ahn,Hongjun Kim,Insoo Jang 대한한방내과학회 2023 大韓韓方內科學會誌 Vol.44 No.3
Objective: This study was conducted to investigate the preventive effect of herbal medicines on restenosis after percutaneous coronary intervention (PCI) by reviewing randomized controlled trials (RCTs). Methods: RCTs were searched for herbal medicine treatment after PCI using eight online databases (PubMed, CNKI, Wanfang, J-STAGE, OASIS, ScienceON, KTKP, and KISS). Studies that confirmed restenosis through coronary angiography at follow-up were selected according to the inclusion and exclusion criteria. The primary outcome was the restenosis rate, and the secondary outcome was the angina recurrence rate. Data were extracted from the final selected studies according to the research methodology and then analyzed with Review Manager 5.4.1. Study quality was assessed using Cochrane's risk-of-bias (RoB) tool. Results: Of the 252 papers obtained through the primary search, nine studies that met the selection criteria were finally selected. In these nine studies, herbal medicine combined with western medicine was used for the experimental group, and western medicine treatment was used alone for the control group. The meta-analysis result revealed that the restenosis rate and angina recurrence rate were significantly lower in the experimental group than in the control group (RR=0.34, 95% CI: 0.22-0.53, p<0.00001, I<sup>2</sup>=0% and RR=0.47, 95% CI: 0.29-0.78, p=0.004, I<sup>2</sup>=0%, respectively). Furthermore, the quality of studies assessed by Cochrane's RoB was low. Conclusions: This study showed that the combined treatment of herbal medicine and western medicine was effective in preventing restenosis and angina after PCI. As the number of papers included in this study was small, a large number of high-quality clinical studies should be considered in the future.