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Chemical constituents from the fungus Chaetomium cupreum RY202
Natcha Panthama,Somdej Kanokmedhakul,Kwanjai Kanokmedhakul,Kasem Soytong 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.5
Two new angular types of azaphilones, isochromophilonol(1) and ochrephilonol (2), together withten known compounds (3–12), were isolated from Chaetomiumcupreum RY202. Their structures were establishedon the basis of spectroscopic data and the absolute configurationsof 1 and 3 were determined by the modifiedMosher’s method. Compounds 1, 2 and 4 showed moderatedcytotoxicity against KB and NCI-H187 cell lines (IC509.63–32.42 lg/mL).