http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Natasha Sheikh (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
High-Rosmarinic Acid Spearmint Tea in the Management of Knee Osteoarthritis Symptoms
A. Erin Connelly,Amy J. Tucker,Hilary Tulk,Marisa Catapang,Lindsey Chapman,Natasha Sheikh,Svitlana Yurchenko,Ron Fletcher,Laima S. Kott,Alison M. Duncan,Amanda J. Wright 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.12
Individuals with medically diagnosed knee osteoarthritis (OA) participated in a randomized, double-blind study to investigate the effects of a high-rosmarinic acid (rosA) spearmint tea. Sixty-two participants were randomized by sex and screening pain score to consume tea brewed from a high-rosA spearmint variety or a commercially available spearmint twice daily for 16 weeks. Pain, quality of life (QoL), and physical function at baseline and week 16 were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Short-Form 36-item Health Survey (SF-36), 6-minute walk test (6MWT), and stair climb test (SCT). Data from 46 participants (mean age = 60.7; BMI = 32.9 kg/m2) were analyzed. Pain score significantly decreased from week 0 to 16 for the high-rosA group but not for the control group and scores for stiffness and physical disability significantly decreased from week 0 to 16 for both groups. Increased QoL score on the bodily pain index in the SF-36 was observed at week 16 within the high-rosA group only, although no significant differences were observed between the groups. A nonsignificant improvement was observed in the 6MWT at week 16 in the high-rosA group only. There were no changes in the SCT for either group. Therefore, 16-week daily consumption of the highrosA and commercial spearmint teas significantly improved stiffness and physical disability scores in adults with knee OA, but only the high-rosA tea significantly decreased pain. Consumption of high-rosA tea warrants further consideration as a potential complementary therapy to reduce pain in OA. Clinical Trial Registration Number: NCT01380015.
-
Munira Shabbir-Moosajee,Samad Jehangir,Sobiya Sawani,Tariq Muhammed,Natasha Ali,Usman Sheikh,Salman Adil 대한혈액학회 2019 Blood Research Vol.54 No.2
BackgroundBendamustine is an attractive option for the management of both de novo and relapsed lymphomas. It is being increasingly used in the conditioning regimen for autologous stem cell transplantation (SCT) and can be an alternative to the traditionally-used carmustine. In this study, we aimed to determine the safety and efficacy of bendamustine in the con-ditioning regimen for autologous SCT in refractory/relapsed lymphomas.MethodsWe designed a descriptive study to evaluate bendamustine in combination with etopo-side, cytarabine, and melphalan (BeEAM) in the conditioning regimen for autologous SCT.ResultsFourteen patients (median age, 28 yr) with Hodgkin’s lymphoma (HL) (N=8), non-Hodgkin’s lymphomas (NHL) (N=5), or peripheral T-cell lymphoma, not otherwise specified (PTCL NOS) (N=1) were included in the study. A median number of 5.95×106CD34+ cells/kg were transfused. Median times to absolute neutrophil count and platelet engraftment were 17 days and 24 days, respectively. The 100-day transplantation mortal-ity rate was 28% (4 patients). Eight patients (57.14%) had GII-III acute kidney injury, four patients (28.5%) had GIII-IV hyperbilirubinemia, and twelve patients (85%) had GII-III diarrhea. After 3 months, 37% (5 patients) and 21.4% (3 patients) demonstrated complete response and partial response, respectively. The median follow-up was 5.5 months (15 days‒19 mo). At the final follow-up, 7 patients (50%) were alive and in CR.ConclusionOur study showed that bendamustine is a potentially toxic agent in the conditioning regi-men for autologous SCT, resulting in significant liver, kidney, and gastrointestinal toxicity. Further studies are required to assess its safety and efficacy at reduced doses.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
