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Tanaka, Yasuo,Saito, Shohei,Mori, Shigeki,Aratani, Naoki,Shinokubo, Hiroshi,Shibata, Naoki,Higuchi, Yoshiki,Yoon, Zin Seok,Kim, Kil Suk,Noh, Su Bum,Park, Jong Kang,Kim, Dongho,Osuka, Atsuhiro WILEY-VCH Verlag 2008 Angewandte Chemie Vol.47 No.4
<B>Graphic Abstract</B> <P>Round the twist: Metalation of [36]octaphyrin 1 provided the Möbius aromatic Pd<SUB>2</SUB> complex 3 as well as the Hückel antiaromatic Pd<SUB>2</SUB> complex 2. This method can be applied to other expanded porphyrins and Group 10 metal ions. The aromatic/antiaromatic character was supported by NMR spectrscopy, NICS calculation, and two-photon absorption measurements. <img src='wiley_img/14337851-2008-47-4-ANIE200704407-content.gif' alt='wiley_img/14337851-2008-47-4-ANIE200704407-content'> </P>
Mitsuru Okuno,Keisuke Iwata,Tsuyoshi Mukai,Yusuke Kito,Takuji Tanaka,Naoki Watanabe,Senji Kasahara,Yuhei Iwasa,Akihiko Sugiyama,Youichi Nishigaki,Yuhei Shibata,Junichi Kitagawa,Takuji Iwashita,Eiichi 대한소화기내시경학회 2024 Clinical Endoscopy Vol.57 No.3
Background/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) using a 19-gauge needle is an efficient sampling method for the diagnosis of lymphadenopathy. This study compared 19-gauge conventional and Franseen needles for the diagnosis of lymphadenopathy and classification of malignant lymphoma (ML). Methods: Patient characteristics, number of needle passes, puncture route, sensitivity, specificity, and accuracy of cytology/histology for lymphadenopathy were analyzed in patients diagnosed with lymphadenopathy by EUS-FNA using conventional or Franseen needles. Results: Between 2012 and 2022, 146 patients met the inclusion criteria (conventional [n=70] and Franseen [n=76]). The median number of needle passes was significantly lower in the conventional group than in the Franseen group (3 [1–6] vs. 4 [1–6], p=0.023). There were no significant differences in cytological/ histological diagnoses between the two groups. For ML, the immunohistochemical evaluation rate, sensitivity of flow cytometry, and cytogenetic assessment were not significantly different in either group. Bleeding as adverse events (AEs) were observed in three patients in the Franseen group. Conclusions: Both the 19-gauge conventional and Franseen needles showed high accuracy in lymphadenopathy and ML classification. Considering sufficient tissue collection and the avoidance of AEs, the use of 19-gauge conventional needles seems to be a good option for the diagnosis of lymphadenopathy.