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      • SCOPUSKCI등재

        Mass Loss and Changes of Nutrients during Decomposition of Phragmites communis at the Fringe of Stream

        Mun, Hueong-Tae,Namgung, Jeong,Namgung, Jeong-Hee-Namgung The Ecological Society of Korea 2000 Journal of Ecology and Environment Vol.23 No.2

        Mass loss and changes of mineral nutrients during decomposition of Phragmites communis for 13 months from November 1998 to December 1999, were investigated at the fringe of stream at Boryeong, Chungnam Province in Korea. Plant materials, which were collected in November 1998. were divided into leaves, culms and rhizomes. Litterbags, 15${\times}$15 cm, were made of nylon mesh with 2-mm$^2$ holes. At 13 months after installation, remaining mass of leaves, culms and rhizomes was 29.0%, 57.4%, 20.6%, respectively. Mass loss rate of the culms was significantly lower than those of the leaves and rhizomes. The decay rate of leaves, culms and rhizomes was 1.21. 0.42 and 1.48 per year, respectively. Initial concentration of N, P, K, Ca and Mg of leaves. culms and rhizomes was 22.5, 9.0, 15.5 mg/g for N, 0.34. 0.10, 0.33 mg/g for P, 15.0, 12.5. 12.3 mg/g for K, 2.84. 0.80, 0.03 mg/g for Ca. 1.94. 0.97, 0.40 mg/g for Mg, respectively. Concentrations of nutrients were higher in leaves than in culms and rhizomes. Except for N and Mg in rhizomes, there was no immobilization period during the decomposition. In the case of remaining K and Ca, most are lost during the first 3 months. Without any suitable method for removal of dead part, eutrophication of freshwater may be accelerated by dead macrophytes.

      • SCISCIESCOPUS

        Cr(OH)<sub>3</sub>(s) Oxidation Induced by Surface Catalyzed Mn(II) Oxidation

        Namgung, Seonyi,Kwon, Man Jae,Qafoku, Nikolla P.,Lee, Giehyeon American Chemical Society 2014 Environmental science & technology Vol.48 No.18

        <P>We examined the feasibility of Cr(OH)<SUB>3</SUB>(s) oxidation mediated by surface catalyzed Mn(II) oxidation under common groundwater pH conditions as a potential pathway of natural Cr(VI) contaminations. Dissolved Mn(II) (50 μM) was reacted with or without synthesized Cr(OH)<SUB>3</SUB>(s) (1.0 g/L) at pH 7.0–9.0 under oxic or anoxic conditions. Homogeneous Mn(II) oxidation by dissolved O<SUB>2</SUB> was not observed at pH ≤ 8.0 for 50 days. At pH 9.0, by contrast, dissolved Mn(II) was completely removed within 8 days and precipitated as hausmannite. When Cr(OH)<SUB>3</SUB>(s) was present, this solid was oxidized and released substantial amounts of Cr(VI) as dissolved Mn(II) was added into the suspension at pH ≥ 8.0 under oxic conditions. Production of Cr(VI) was attributed to Cr(OH)<SUB>3</SUB>(s) oxidation by a newly formed Mn oxide via Mn(II) oxidation catalyzed on Cr(OH)<SUB>3</SUB>(s) surface. XANES results indicated that this surface-catalyzed Mn(II) oxidation produced a mixed valence Mn(III/IV) solid phase. Our results suggest that toxic Cr(VI) can be naturally produced via Cr(OH)<SUB>3</SUB>(s) oxidation coupled with the oxidation of dissolved Mn(II). In addition, this study evokes the potential environmental hazard of sparingly soluble Cr(OH)<SUB>3</SUB>(s), which has been considered the most common and a stable remediation product of Cr(VI) contamination.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/esthag/2014/esthag.2014.48.issue-18/es503018u/production/images/medium/es-2014-03018u_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/es503018u'>ACS Electronic Supporting Info</A></P>

      • SCIESCOPUSKCI등재

        Effects of Supplementary Blood Meal on Carnosine Content in the Breast Meat and Laying Performance of Old Hens

        Namgung, N.,Shin, D.H.,Park, S.W.,Paik, I.K. Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.7

        The objective of this research was to evaluate the effects of dietary supplementation of blood meal (BM) as a source of histidine, and magnesium oxide (MgO) as a catalyst of carnosine synthetase, on carnosine (L-Car) content in the chicken breast muscle (CBM), laying performance, and egg quality of spent old hens. Four hundred eighty laying hens (Hy-Line$^{(R)}$ Brown), 95wk old, were allotted randomly into five replicates of six dietary treatments: T1; 100% basal diet, T2; 100% basal diet+MgO, T3; 97.5% basal diet+2.5% BM, T4; 97.5% basal diet+2.5% BM+MgO, T5; 95% basal diet+5% BM, T6; 95% basal diet+5% BM+MgO. Magnesium oxide was added at 0.3% of diets. The layers were fed experimental diets for 5wk. There were no significant differences in the weekly L-Car content in CBM among all treatments during the total experimental period, but some of the contrast comparisions showed higher L-Car in CBM of T6. The L-Car contents linearly decreased (p<0.01 or p<0.05) as the layers got older except in T4 (p>0.05). There were significant differences in egg weight (p<0.01) and soft and broken egg ratio (p<0.05). The control (T1) was highest in egg weight and T6 was lowest in soft and broken egg ratio. Among the parameters of egg quality, there were significant differences in eggshell strength (p<0.01) and egg yolk color (p<0.05). Magnesium oxide supplementation increased the eggshell strength and BM tended to decrease egg yolk color. Eggshell color, eggshell thickness, and Haugh unit were not influenced by BM and MgO. In conclusion, BM and MgO did not significantly influence the L-Car in CBM of spent layers. The L-Car content rapidly decreased as the layers became senescent. Eggshell strength was increased by MgO supplementation.

      • SCOPUSKCI등재

        Weight Loss and Nutrient Dynamics during Leaf Litter Decomposition of Quercus variabilis and Pinus densiflora at Mt. Worak National Park

        NamGung, Jeong,Han, A-Reum,Mun, Hyeong-Tae The Ecological Society of Korea 2008 Journal of Ecology and Environment Vol.31 No.4

        Weight loss and nutrient dynamics of oak and pine leaf litter during decomposition were investigated from December 2005 through June 2008 at Mt. Worak National Park as a part of National Long-Term Ecological Research Program in Korea. The decay constant (k) of oak and pine leaf litter were 0.314 and 0.217, respectively. After 30 months decomposition, remaining weight of oak and pine leaf litter was 45.5% and 58.1%, respectively. Initial C/N ratio of oak and pine leaf litter was 53.4 and 153.0, respectively. Carbon % of initial oak and pine leaf litter was similar with each other; however, nitrogen content of initial oak leaf litter (0.85%) was greater than that of initial pine leaf litter (0.33%). N and P concentration in both decomposing leaf litter increased significantly during decomposition. There was no net N and P mineralization period in decomposing pine leaf litter. K, Ca and Mg concentration in both decomposing leaf litter showed different pattern with those of N and P. After 30 months decomposition, remaining nutrients in oak and pine leaf litter were 97.7 and 216.2% for N, 123.2 and 216.5% for P, 39.3 and 44.8% for K, 47.9 and 40.6% for Ca, 30.7 and 51.2% for Mg, respectively.

      • SCISCIESCOPUS

        Dual bio-responsive gene delivery via reducible poly(amido amine) and survivin-inducible plasmid DNA

        Namgung, Ran,Brumbach, Jonathan H.,Jeong, Ji Hoon,Yockman, James W.,Kim, Sung Wan,Lin, Chao,Zhong, Zhiyuan,Feijen, Jan,Engbersen, Johan F. J.,Kim, Won Jong Springer-Verlag 2010 Biotechnology letters Vol.32 No.6

        <P>A bioreducible poly(amido amine) (SS-PAA) gene carrier, known as poly (amido-butanol) (pABOL), was used to transfect a variety of cancer and non-cancer cell lines. To obtain cancer-specific transgene expression for therapeutic efficiency in cancer treatment, we constructed survivin-inducible plasmid DNA expressing the soluble VEGF receptor, sFlt-1, downstream of the survivin promoter (pSUR-sFlt-1). Cancer-specific expression of sFlt-1 was observed in the mouse renal carcinoma (RENCA) cell line. pABOL enhanced the efficiency of gene delivery compared to traditional carriers used in the past. Thus, a dual bio-responsive gene delivery system was developed by using bioreducible p(ABOL) for enhanced intracellular gene delivery and survivin-inducible gene expression system (pSUR-sFlt-1 or pSUR-Luc reporter gene) that demonstrates increased gene expression in cancer that has advantages over current gene delivery systems.</P>

      • KCI등재
      • SCIESCOPUS

        <i>Prunella vulgaris</i> Attenuates Diabetic Renal Injury by Suppressing Glomerular Fibrosis and Inflammation

        Namgung, Seung,Yoon, Jung Joo,Yoon, Chi-Su,Han, Byung Hyuk,Choi, Eun Sik,Oh, Hyuncheol,Kim, Youn-Chul,Lee, Yun Jung,Kang, Dae Gill,Lee, Ho Sub Institute for Advanced Research in Asian Science a 2017 The American journal of Chinese medicine Vol. No.

        <P>Diabetic nephropathy is both the most common complication and the leading cause of mortality associated with diabetes. <I>Prunella vulgaris</I>, a well-known traditional medicinal plant, is used for the cure of abscess, scrofula, hypertension and urinary diseases. This study confirmed whether an aqueous extract of <I>Prunella vulgaris</I> (APV) suppresses renal inflammation and fibrosis. In human mesangial cell (HMC), pretreatment of APV attenuated 25<TEX>$ \,$</TEX>mM HG-induced suppressed TGF-<TEX>$ \beta $</TEX> and Smad-2/4 expression; it increased the expression level of Smad-7. Connective tissue growth factor (CTGF) and collagen IV, fibrosis biomarkers, were significantly decreased by APV. APV suppressed inflammatory factors such as intracellular cell adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein-1 (MCP-1). APV inhibited activation and translocation of nuclear factor kappa-B (NF-<TEX>$ \kappa $</TEX>B) in HG-stimulated HMCs. Moreover, APV significantly improved HG-induced ROS in a dose-dependent manner. In diabetic rat models, APV significantly decreased blood glucose, blood urea nitrogen (BUN) and ameliorated plasma creatinine (PCr). APV reduced the PAS positivity staining intensity and basement membrane thickening in glomeruli of diabetic rats. Fibrosis related proteins such as collagen IV and TGF-<TEX>$ \beta $</TEX>1 were also inhibited by APV. These results suggest that APV has a significant protective effect against diabetic renal dysfunction including inflammation and fibrosis through disruption of the TGF-<TEX>$ \beta $</TEX>/Smad signaling. Therefore, APV may be useful in potential therapies that target glomerulonephritis and glomerulosclerosis, which lead to diabetic nephropathy.</P>

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