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- 저자 : N.P. Kataria (검색결과 2 건)
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The smart PFD with LRB for seismic protection of the horizontally curved bridge
N.P. Kataria,R.S. Jangid 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.5
Recently, number of smart material are investigated and widely used in civil construction and other industries. Present study investigates the application of smart semi-active piezoelectric friction damper (PFD) made with piezoelectric material for the seismic control of the horizontally curved bridge isolated with lead rubber bearing (LRB). The main aim of the study is to investigate the effectiveness of hybrid system and to find out the optimum parameters of PFD for seismic control of the curved bridge. The selected curved bridge is a continuous three-span concrete box girder supported on pier and rigid abutment. The PFD is located between the deck and abutments or piers in chord and radial directions. The bridge is excited with four different earthquake ground motions with all three components (i.e. two horizontal and a vertical) having different characteristics. It is observed that the use of semi-active PFD with LRB is quite effective in controlling the response of the curved bridge as compared with passive system. The incorporation of the smart damper requiring small amount of energy in addition with an isolation system can be used for effective control the curved bridge against the dynamic loading.
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Malik, Y.P.S.,Chakravarti, S.,Sharma, K.,Vaid, N.,Rajak, K.K.,Balamurugan, V.,Biswas, S.K.,Mondal, B.,Kataria, R.S.,Singh, R.K. Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.7
Toll-like receptors (TLRs) play an important role in the recognition of invading pathogens and the modulation of innate immune responses in mammals. The TLR4 and TLR7 are well known to recognize the bacterial lipopolysaccharide (LPS) and single stranded (ssRNA) ligands, respectively and play important role in host defense against Gram-negative bacteria and ssRNA viruses. In the present study, coding exon fragments of these two TLRs were identified, cloned, sequenced and analyzed in terms of insertion-deletion polymorphism, within bovine TLRs 4 and 7, thereby facilitating future TLR signaling and association studies relevant to bovine innate immunity. Comparative sequence analysis of TLR 4 exons revealed that this gene is more variable, particularly the coding frame (E3P1), while other parts showed percent identity of 95.7% to 100% at nucleotide and amino acid level, respectivley with other Bos indicus and Bos taurus breeds from different parts of the world. In comparison to TLR4, sequence analysis of TLR7 showed more conservation among different B. indicus and B. taurus breeds, except single point mutation at 324 nucleotide position (AAA to AAM) altering a single amino acid at 108 position (K to X). Percent identity of TLR7 sequences (all 3 exons) was between 99.2% to 100% at nucleotide and amino acid level, when compared with available sequence database of B. indicus and B. taurus. Simple Modular Architecture Research Tool (SMART) analysis showed variations in the exon fragments located in the Leucine Rich Repeat (LRR) region, which is responsible for binding with the microbial associated molecular patterns and further, downstream signaling to initiate anti-microbial response. Considering importance of TLR polymorphism in terms of innate immunity, further research is warranted.
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