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지역사회 거주 고령자 대상의 교통안전 보행 교육 사업의 사례연구
이민홍(Minhong Lee),송승옥(Seung Ok Song),한정미(Jung Mi Han),김예은(Ye Eun Kim) 한국노년학연구회 2024 한국 노년학연구 Vol.33 No.2
누구나 나이에 상관없이 보행 중에 발생한 교통사고의 피해자가 될 수 있지만, 그 피해자의 절대다수는 고령자들이다. 이에 본 연구는 교통사고 예방을 위한 교육 프로그램의 효과를 살피기 위한 목적으로 지역사회에 거주하는 고령자 대상 교통안전 보행 교육 사업 관련 사례의 효과를 살펴보았다. 이 사업에 참여한 자는 지역사회에 거주하는 고령자 891명이었는데, 그들은 모두 해당 지역사회 노인복지관 회원들이었다. 사업의 효과는 교통안전 지식, 교통표지판 지식, 교통안전 행동, 그리고 주관적 교통안전 역량이라는 네 영역의 프로그램 참여 이전과 이후의 변화를 비교한 것이었다. 비교한 결과, 네 영역에서 모두 교육 프로그램의 참여 효과가 드러났다. 참여자의 특성을 토대로 비교한 결과에서는 여성, 교육이나 생활 수준이 낮은 자, 나이가 더 많은 고령자 등에서 그 효과가 더 두드러졌다. 본 사업의 효과성을 근거로 고령자 교통안전 역량을 증진할 수 있는 안전 보행 교육 사업의 지속성을 논했으며, 아울러 고령자의 특성에 맞는 맞춤형 교육 그리고 행동 기반의 교육 등을 제안했다. Anyone of any age can be a victim of a traffic accident as a pedestrian, but the vast majority of the victims are older adults. Therefore, in this study, we examined the effectiveness of a case study on a traffic safety pedestrian education program for the community-dwelling older adults to examine the effectiveness of an education program for preventing traffic accidents. The participants in the program were 891 adults, all of them were members of senior welfare centers located in their residential area. The effectiveness of the program was assessed by comparing changes before and after program participation in four domains; traffic safety knowledge, traffic sign knowledge, traffic safety behavior, and subjective traffic safety competence. The findings showed that the educational program had a positive effect in all of four domains. Comparing the characteristics of the participants, the effect was more pronounced for women, people with low education or living standards, and the older. Based on the findings, the study advocates that the safe walking education programs should be continuously implemented to enhance the traffic safety capabilities of the older adults. The researchers also recommend tailoring education and behavior-based training to the specific characteristics of each older adult.
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Optimization Layout of Anhui Provincial Construction Engineering Quality Inspection Institutions
Yingrui Wang,Heping Pan,Minhong Ye 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.3
Construction engineering quality inspection is an important means to ensure the quality and safe use of construction engineering. On the base of analyzing the status and the main problems of Anhui provincial construction engineering quality inspection institutions, the five principles were proposed to put forward the total control, optimize the structure and increase and development ability, moderate competition and standard development. By optimizing the detection mechanism, enhancing the overall level of the testing agencies, and strengthening supervision, to achieve a basic balance and reasonable layout of supply and demand in various cities and regions. It provides reference for the research and practice of the supervision and management of construction engineering quality test institutions.
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Weiguang Gu,Hua Zhang,Yiyu Lu,Minjing Li,Shuang Yang,Jianmiao Liang,Zhijian Ye,Zhihua Li,Minhong He,Xiaoliang Shi,Fei Wang,Dong You,Weiquan Gu,Weineng Feng 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3
Purpose We aimed to evaluate whether the addition of pemetrexed is effective in improving progression-free survival (PFS) in epidermal growth factor receptor (EGFR)–mutated patients with or without concomitant alterations. Materials and Methods This multicenter clinical trial was conducted in China from June 15, 2018, to May 31, 2019. A total of 92 non–small cell lung cancer (NSCLC) patients harboring EGFR-sensitive mutations were included and divided into concomitant and non-concomitant groups. Patients in each group were randomly treated with EGFR–tyrosine kinase inhibitor (TKI) monotherapy or EGFR-TKI combined with pemetrexed in a ratio of 1:1. PFS was recorded as the primary endpoint. Results The overall median PFS of this cohort was 10.1 months. There were no significant differences in PFS between patients with and without concomitant and between patients received TKI monotherapy and TKI combined with pemetrexed (p=0.210 and p=0.085, respectively). Stratification analysis indicated that patients received TKI monotherapy had a significantly longer PFS in non-concomitant group than that in concomitant group (p=0.002). In concomitant group, patients received TKI combined with pemetrexed had a significantly longer PFS than patients received TKI monotherapy (p=0.013). Molecular dynamic analysis showed rapidly emerging EGFR T790M in patients received TKI monotherapy. EGFR mutation abundance decreased in patients received TKI combined chemotherapy, which supports better efficacy for a TKI combined chemotherapy as compared to TKI monotherapy. A good correlation between therapeutic efficacy and a change in circulating tumor DNA (ctDNA) status was found in 66% of patients, supporting the guiding role of ctDNA minimal residual disease (MRD) in NSCLC treatment. Conclusion EGFR-TKI monotherapy is applicable to EGFR-sensitive patients without concomitant alterations, while a TKI combined chemotherapy is applicable to EGFR-sensitive patients with concomitant alterations. CtDNA MRD may be a potential biomarker for predicting therapeutic efficacy.
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