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Ecren Uzun Yaylaci,Murat Yaylaci,Mehmet Emin Ozdemir,Merve Terzi,Sevval Ozturk Techno-Press 2023 Advances in nano research Vol.15 No.2
The study investigated the effect of geometric structures of nano-patterned surfaces, such as peak sharpness, height, width, aspect ratio, and spacing, on mechano-bactericidal properties. Here, in silico models were developed to explain surface interactions with Escherichia coli. Numerical solutions were performed based on the finite element method and verified by the artificial neural network method. An E. coli cell adhered to the nano surface formed elastic and creep deformation models, and the cells' maximum deformation, maximum stress, and maximum strain were calculated. The results determined that the increase in peak sharpness, aspect ratio, and spacing values increased the maximum deformation, maximum stress, and maximum strain on E. coli cell. In addition, the results showed that FEM and ANN methods were in good agreement with each other. This study proved that the geometrical structures of nano-patterned surfaces have an important role in the mechano-bactericidal effect.
Ali Benouis,Mohammed El Sallah Zagane,Abdelmadjid Moulgada,Murat Yaylacı,Djafar Ait Kaci,Merve Terzi,Mehmet Emin Özdemir,Ecren Uzun Yaylacı 국제구조공학회 2024 Structural Engineering and Mechanics, An Int'l Jou Vol.89 No.5
This study examines crack behavior within orthopedic cement utilized in total hip replacements through the finite element method. Its main goal is to compute stress intensity factors (SIF) near the crack tip. The analysis encompasses two load types, static and dynamic, applied to a crack starting from the interface between the cement and bone. Specifically, it investigates SIFs under mixed mode conditions during three activities: normal walking, climbing upstairs, and downstairs. The results highlight that a crack originating from a micro-interface under substantial loading can cause cement damage, leading to prosthetic loosening. Stress intensity factors in modes I, II, and III are influenced by the crack tip’s orientation and location in the bone cement, with a 90° orientation yielding notably higher values across all three modes.