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Masuda Satoshi,Takagi Kenta,Dong Wei,Kawasaki Akira 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
Monosized germanium micro particles are prepared by a newly developed Pulsated Orifice Ejection Method. The obtained particles are categorized into two kinds of the microstructures as refined and coarse ones. The morphological difference is estimated to be determined by the undercooling level during nucleation. Actually, the increase in the temperature of the melt was effective in coarsening the microstructure, because the temperature of the melt intensely relates to the undercooling level. The transition temperature of coarse and refined microstructures is found to be 1300-1350K. Furthermore, a triggered nucleation could improve the crystallinity of the particles in the short separation.
Furuta Satoshi,Masuda Shinsuke 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
Free-machining agent 'KSX' contains complex calcium oxide is developed. The effect of admix ratio of KSX on mechanical properties and machinability with two different cutting speeds is reported. KSX displays improved machinability without deterioration of mechanical properties up to 0.3mass% addition. It was observed that KSX is effective with a small addition of 0.1mass% at slower cutting speed, and increased of admix ratio is effective at faster cutting speed.
Igawa, Satoshi,Sato, Yuichi,Ishihara, Mikiko,Kasajima, Masashi,Kusuhara, Seiichiro,Nakahara, Yoshiro,Otani, Sakiko,Fukui, Tomoya,Katagiri, Masato,Sasaki, Jiichiro,Masuda, Noriyuki Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.7
Background: Pemetrexed monotherapy has come to be recognized as one of the standard second-line therapies for advanced non-squamous non-small cell lung cancer (NSCLC). However, there have been no reports of studies that have evaluated the efficacy of pemetrexed according to type of active EGFR mutation, i.e., an exon 19 deletion or an L858R point mutation. Materials and Methods: The records of non-squamous NSCLC patients harboring an EGFR mutation who received pemetrexed monotherapy as a second or later line of chemotherapy at Kitasato University Hospital between March 2010 and October 2015 were retrospectively reviewed, and the treatment outcomes were evaluated. Results: The overall response rate and progression-free survival time (PFS) of the 53 patients with non-squamous NSCLC were 15.1% and 2.3 months, respectively. There were significant differences between the disease control rate (37.5% vs. 76.2%) and PFS time (1.8 months vs. 3.3 months) of the exon 19 deletion group and the L858R point mutation group, and a multivariate analysis identified type of EGFR mutation as well as performance status (PS) as independent predictors of PFS. Conclusions: The clinical data obtained in this study provided a valuable rationale for considering type of EGFR mutation as well as non-squamous histology as predictors of the efficacy of pemetrexed monotherapy.
Dong Wei,Masuda Satoshi,Takagi Kenta,Kawasaki Akira 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
Mono-sized silicon particles were effectively fabricated by a novel way named pulsated orifice ejection method (POEM). The particles are with very narrow particles size distribution and very small standard deviation of mean particle size. There are two different types spherical silicon particles were found. One consists of many grains mainly in random boundaries. The other consists of two or three grains with only twin orientation relationships, even single crystal in cross-section was also found within this type of spherical silicon particles.
? Research Activities on MIR-FEL and table top THz Generation inKyoto University
OHGAKI, Hideaki,KII, Toshiteru,MASUDA, Kai,Arby, ABDEL AZIEM MAHMOUD Bakr,HIGASHIMURA, Keisuke,KINJO, Ryota,YOSHIDA, Kyohei,UEDA, Satoshi,SONOBE, Taro,Uk, Jeong Young Korean Physical Society 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.2
Eisuke Miura,Shin-ichi Masuda,Takanori Ooyama,Satoshi Ishii 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.1
The generation of quasi-monoenergetic electron beams containing more than 3 × 108 electrons in a monoenergetic peak for energies from 40 to 60 MeV has been demonstrated. The quasimonoenergetic electron beams have been obtained from a plasma with an electron density of 1.6 × 1019 cm−3 produced by an 8-TW, 50-fs Ti:sapphire laser pulse. It is necessary to control the plasma density precisely and to suppress the nanosecond prepulse with the main pulse for stable generation of quasi-monoenergetic beams. Two-dimensional particle-in-cell simulation results are also shown. The simulation result suggests that quasi-monoenergetic beam generation is brought about by matching the laser propagation length with the gas jet length.