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      • SCOPUSKCI등재
      • Exact Analysis and Physical Realization of the 6-Lobe Chua Corsage Memristor

        Mannan, Zubaer I.,Yang, Changju,Adhikari, Shyam P.,Kim, Hyongsuk Hindawi Limited 2018 Complexity Vol.2018 No.-

        <P>A novel generic memristor, dubbed the <I>6-lobe Chua corsage memristor</I>, is proposed with its nonlinear dynamical analysis and physical realization. The proposed corsage memristor contains <I>four</I> asymptotically stable equilibrium points on its complex and diversified dynamic routes which reveals a <I>4-state nonlinear memory device</I>. The higher degree of versatility of its dynamic routes reveal that the proposed memristor has a variety of dynamic paths in response to different initial conditions and exhibits a highly nonlinear <I>contiguous</I> DC <I>V</I>-<I>I</I> curve. The DC <I>V</I>-<I>I</I> curve of the proposed memristor is endowed with an explicit <I>analytical parametric representation</I>. Moreover, the derived <I>three formulas</I>, exponential trajectories of state <TEX>$ x_{n}\left(t\right)$</TEX> , time period <TEX>$ t_{fn}$</TEX> , and minimum pulse amplitude <TEX>$ V_{A}$</TEX> , are required to analyze the movement of the state trajectories on the piecewise linear (PWL) dynamic route map (DRM) of the corsage memristor. These <I>formulas</I> are universal, that is, applicable to any <I>PWL DRM curves</I> for any <I>DC</I> or <I>pulse input</I> and with any <I>number of segments</I>. Nonlinear dynamics and circuit and system theoretic approach are employed to explain the <I>asymptotic quad-stable behavior</I> of the proposed corsage memristor and to <I>design</I> a <I>novel real memristor emulator</I> using <I>off-the-shelf</I> circuit components.</P>

      • KCI등재

        In-Vitro Anticancer and Free Radical Scavenging Potential of Compound Formulation Used in Unani System of Medicine

        Mannan, Mohd Nazir,Kazmi, Munawwar Husain,Chakraborty, Alokananda,Zakir, Mohammad,Ahmad, Tasleem,Lahari, K. Cellmed Orthocellular Medicine and Pharmaceutical 2020 셀메드 (CellMed) Vol.10 No.4

        Cancer is one of the leading cause of mortality in India as well as worldwide. The management of cancer by conventional therapy has shown life threatening adverse effects. The researchers are now exploring the natural way of treatment. Unani system of medicine have rich literature for cancer and many compound formulations have been described in this system. Unani system of medicine is based on holistic approach and treat human being as a unit with natural herbs, mineral and animal origin drugs. An important compound Unani formulation (CUF) from the literature has been chosen to explore the Unani claim of its anticancer activity. The phytochemical constituents were assessed using standard phytochemical screening method. Antioxidant property of this formulation was assessed by DPPH assay. The DPPH free radical scavenging assay was carried out by colorimetric method and ascorbic acid was taken as a positive control. Three different extracts of CUF on different concentrations were used to screening on human breast cancer (BCC) MCF-7 cell line. For the estimation of in-vitro cytotoxic potency of the investigated extracts was assessed on MTT assay by using trypan blue method and paclitaxel was used as the standard. Hydro-ethanolic (HE) extract showed highest free radical scavenging activity among all extracts. DPPH Assay showed substantial antioxidant activity of these extracts in hydro-ethanol extract at 1㎍ concentration of CUF. The CUF showed antioxidant and anticancer activity. The claim made by Unani physician has been proved.

      • Effect of EOG Signal Filtering on the Removal of Ocular Artifacts and EEG-Based Brain-Computer Interface: A Comprehensive Study

        Mannan, Malik M. Naeem,Kamran, M. Ahmad,Kang, Shinil,Jeong, Myung Yung Hindawi Limited 2018 Complexity Vol.2018 No.-

        <P>It is a fact that contamination of EEG by ocular artifacts reduces the classification accuracy of a brain-computer interface (BCI) and diagnosis of brain diseases in clinical research. Therefore, for BCI and clinical applications, it is very important to remove/reduce these artifacts before EEG signal analysis. Although, EOG-based methods are simple and fast for removing artifacts but their performance, meanwhile, is highly affected by the bidirectional contamination process. Some studies emphasized that the solution to this problem is low-pass filtering EOG signals before using them in artifact removal algorithm but there is still no evidence on the optimal low-pass frequency limits of EOG signals. In this study, we investigated the optimal EOG signal filtering limits using state-of-the-art artifact removal techniques with fifteen artificially contaminated EEG and EOG datasets. In this comprehensive analysis, unfiltered and twelve different low-pass filtering of EOG signals were used with five different algorithms, namely, simple regression, least mean squares, recursive least squares, REGICA, and AIR. Results from statistical testing of time and frequency domain metrics suggested that a low-pass frequency between 6 and 8 Hz could be used as the most optimal filtering frequency of EOG signals, both to maximally overcome/minimize the effect of bidirectional contamination and to achieve good results from artifact removal algorithms. Furthermore, we also used BCI competition IV datasets to show the efficacy of the proposed framework on real EEG signals. The motor-imagery-based BCI achieved statistically significant high-classification accuracies when artifacts from EEG were removed by using 7 Hz low-pass filtering as compared to all other filterings of EOG signals. These results also validated our hypothesis that low-pass filtering should be applied to EOG signals for enhancing the performance of each algorithm before using them for artifact removal process. Moreover, the comparison results indicated that the hybrid algorithms outperformed the performance of single algorithms for both simulated and experimental EEG datasets.</P>

      • KCI등재

        Assessment of Genetic Divergence in Salt Tolerance of Soybean (Glycine max L.) Genotypes

        Mannan, M.A.,Karim, M.A.,Khaliq, Q.A.,Haque, M.M.,Mian, M.A.K.,Ahmed, J.U. 한국작물학회 2010 Journal of crop science and biotechnology Vol.13 No.1

        A large number of soybean (Glycine max L.) genotypes of diverse growth habit and adaptive characters were used in the experiment. Soil salinity-induced changes in nine morpho-physiological characters of 30-day-old seedlings of 170 soybean genotypes were compared in the study. The first and second principal components (PC) of principal component analysis (PCA) results accounted for 97 and 2.5%, respectively, of the total variations of soybean genotypes. The variation for the first PC was composed mainly of relative total dry weight (DW), relative shoot dry weight, as well as petiole dry weight. There were four clusters distinguished in the cluster analysis. The genotypes in cluster IV performed better in respect to relative total dry weight and relative shoot dry weight and hence having salt tolerance. The genotypes clusters III performed very poorly and those of clusters II and I were moderate to poor. $D^2$ analysis indicated that the clusters differed significantly from each other. Discriminant function analysis (DFA) again asserts strongly that more than 92% of the genotypes were correctly assigned to clusters. Both PCA and DFA confirmed that the relative total DW followed by shoot and petiole DW were the major discriminatory variables, and the root DW were the secondary important variables to distinguish genotypes into groups. In this study, multivariate analyses were used in identifying the soybean genotypes of desirable traits for salt tolerance.

      • Energy Model Based Direct Torque Control of Induction Motor Using IP Controllers

        Mannan, Mohammad Abdul,Murata, Toshiaki,Tamura, Junji Journal of International Conference on Electrical 2012 Journal of international Conference on Electrical Vol.1 No.4

        This paper deals with direct torque control of an induction motor (IM) with constant switching frequency. The desired torque is obtained from the speed controller which is designed using the IP controller. Decoupling control of torque and flux is developed based on the energy model of IM using the IP controller strategies. The desired d-axis and q-axis stator voltage components are obtained from the designed controller, which decouples torque and flux. The constant switching frequency can be applied using space-vector pulse width modulation, since the desired stator voltage can be known from the decoupling torque and flux controllers. In order to achieve stable operation of the proposed IP controllers, the gains of the controllers are chosen by setting the poles in negative (left) half of s-plane and by choosing the rising time for the response of the step function. The proposed controller was verified in simulations using Matlab/Simulink and results have proven excellent performance. It was found that the proposed IP controllers can provide excellent performance to track the desired torque and speed and to reject the disturbance of load.

      • SCISCIESCOPUS
      • KCI등재

        Standardization and Development of Pharmacopoeial Standard Operating Procedures (SOPs) of Classical Unani Formulation

        Mannan, Mohd Nazir,Kazmi, Munawwar Husain,Zakir, Mohammad,Naikodi, Mohammed Abdul Rasheed,Zahid, Uzma,Siddiqui, Javed Inam Cellmed Orthocellular Medicine and Pharmaceutical 2020 셀메드 (CellMed) Vol.10 No.2

        Standardization of drug deals with confirmation of drug identity and determination of drug quality and purity. Unani herbal formulations are used in traditional medicine for the treatment of various diseases. Cancer is a disease which causes abnormal, uncontrolled growth of body tissue or cells, which tend to proliferate in an uncontrolled way. Spread of cancer from site of origin to other organs of the body is called metastasis. It is a hyper proliferative disorder involving, transformation, dysregulation of apoptosis, invasion and angiogenesis. The present study aimed to standardize a classical Unani formulation (CUF) described as anticancer properties. The CUF has been used for anti-cancerous activity (Dāfi'-i-saraṭān) in human population by Unani physicians for centuries. The standardization parameters carried out for classical Unani formulation are pharmacognostical studies, physicochemical parameters, high-performance thin layer chromatography (HPTLC), microbial load, aflatoxins, and heavy metals revealing specific identities and to evaluate Pharmacopoeial standards. Experiment and the data obtained established the Pharmacopoeial standards for this formulation for identification and quality control purpose. The CUF has been successfully standardized and standard operating procedures (SOPs) for its preparation has been laid down which may serve as a standard reference in future. The standardization data of this formulation may be used as a standard guideline for preparation of the formulation in future.

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