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      • Brake Lining Can be Applied to Super High Speed Vehicle

        Nakano Satoru,Maejima Takashi 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        A new material was developed to achieve improvement of heat durability, improvement of wear resistance, stability of friction coefficient and reduction in aggression to counterpart, because it is difficult to maintain braking properties by using currently available materials in the train wagons used for high-speed transportation. As a result, the new material showed a stable wear resistance even in the speed range of 350km/h, where improvement was also confirmed in reduction of aggression to counterpart material by more than approximately 10%. This development was adopted for the brake lining in the Taiwan High Speed Rail project.

      • Abstract : Soil washing for rice paddy soils contaminated with cadmium

        ( Tomoyuki Makinoa ),( Takashi Kamiya ),( Naoki Sekiya ),( Yuji Maejima ),( Ikuko Akahane ),( Hiroyuki Takano ) 한국환경농학회 2012 한국환경농학회 워크샵자료 Vol.2012 No.2

        Codex Alimentarius Commission (Codex) has adopted the maximum permissible concentration of cadmium (Cd) in polished rice and other relevant crops, which requires an alleviation of the Cd contamination in rice grain. Various chemicals were tested for their Cd extraction efficiency by using three paddy soils, selecting ferric chloride (FeCl3) as a promising chemical for on-site soil washing. The comparison of FeCl3 extraction ability to that of various iron, manganese, and zinc salts revealed the primary extraction mechanism of FeCl3 to be proton release coupled with hydroxide generation (hydrolysis). This indicates that proton release from FeCl3 is controlled by the chemical equilibrium of hydroxide formation, and minimizes the negative effect on soil properties and environment, which are different from hydrochloric acid (HCl). Washing with FeCl3 led to the formation of Cd?chloride complexes, enhancing Cd extraction from the soils. We also developed in situ three-step washing method for Cd-contaminated paddy fields with FeCl3. The method was comprised of 1) chemically washing the field soil with a FeCl3 solution; 2) washing the treated soil with water to eliminate residual Cd and FeCl3; and 3) on-site treatment of wastewater using a portable wastewater treatment system. Concentrations of Cd in the treated water were below Japan`s environmental quality standard (0.01 mg L-1). The on-site soil washing confirmed the effectiveness of FeCl3 for decreasing Cd in soil and rice grains without negative effect on rice yield.

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        Phospholipase Cβ Serves as a Coincidence Detector through Its Ca<sup>2+</sup> Dependency for Triggering Retrograde Endocannabinoid Signal

        Hashimotodani, Yuki,Ohno-Shosaku, Takako,Tsubokawa, Hiroshi,Ogata, Hidenori,Emoto, Ken,Maejima, Takashi,Araishi, Kenji,Shin, Hee-Sup,Kano, Masanobu Elsevier 2005 Neuron Vol.45 No.2

        <P><B>Abstract</B></P><P>Endocannabinoids mediate retrograde signal and modulate transmission efficacy at various central synapses. Although endocannabinoid release is induced by either depolarization or activation of G<SUB>q/11</SUB>-coupled receptors, it is markedly enhanced by the coincidence of depolarization and receptor activation. Here we report that this coincidence is detected by phospholipase Cβ1 (PLCβ1) in hippocampal neurons. By measuring cannabinoid-sensitive synaptic currents, we found that the receptor-driven endocannabinoid release was dependent on physiological levels of intracellular Ca<SUP>2+</SUP> concentration ([Ca<SUP>2+</SUP>]<SUB>i</SUB>), and markedly enhanced by depolarization-induced [Ca<SUP>2+</SUP>]<SUB>i</SUB> elevation. Furthermore, we measured PLC activity in intact neurons by using exogenous TRPC6 channel as a biosensor for the PLC product diacylglycerol and found that the receptor-driven PLC activation exhibited similar [Ca<SUP>2+</SUP>]<SUB>i</SUB> dependence to that of endocannabinoid release. Neither endocannabinoid release nor PLC activation was induced by receptor activation in PLCβ1 knockout mice. We therefore conclude that PLCβ1 serves as a coincidence detector through its Ca<SUP>2+</SUP> dependency for endocannabinoid release in hippocampal neurons.</P>

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