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- 저자 : Liquan Wu (검색결과 4 건)
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Instance segmentation with pyramid integrated context for aerial objects
Juan Wang,Liquan Guo,Minghu Wu,Guanhai Chen,Zishan Liu,Yonggang Ye,Zetao Zhang 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.3
Aerial objects are more challenging to segment than normal objects, which are usually smaller and have less textural detail. In the process of segmentation, target objects are easily omitted and misdetected, which is problematic. To alleviate these issues, we propose local aggregation feature pyramid networks (LAFPNs) and pyramid integrated context modules (PICMs) for aerial object segmentation. First, using an LAFPN, while strengthening the deep features, the extent to which low-level features interfere with high-level features is reduced, and numerous dense and small aerial targets are prevented from being mistakenly detected as a whole. Second, the PICM uses global information to guide local features, which enhances the network's comprehensive understanding of an entire image and reduces the missed detection of small aerial objects due to insufficient texture information. We evaluate our network with the MS COCO dataset using three categories: airplanes, birds, and kites. Compared with Mask R-CNN, our network achieves performance improvements of 1.7%, 4.9%, and 7.7% in terms of the AP metrics for the three categories. Without pretraining or any postprocessing, the segmentation performance of our network for aerial objects is superior to that of several recent methods based on classic algorithms.
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Glioma Stem Cell-Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma
Baowei Ji,Qianxue Chen,Baohui Liu,Liquan Wu,Daofeng Tian,Zhentao Guo,Wei Yi 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.1
Purpose: Cancer stem cells have recently been thought to be closely related to tumor development and reoccurrence. It may be a promising way to cure malignant glioma by using glioma stem cell-targeted dendritic cells as a tumor vaccine. In this study, we explored whether pulsing dendritic cells with antigens of glioma stem cells was a potent way to induce specific cytotoxic T lymphocytes and anti-tumor immunity. Materials and Methods: Cancer stem cells were cultured from glioma cell line U251. Lysate of glioma stem cells was obtained by the repeated freezing and thawing method. Dendritic cells (DCs) were induced and cultured from the murine bone marrow cells, the biological characteristics were detected by electron microscope and flow cytometry. The DC vaccine was obtained by mixing DCs with lysate of glioma stem cells. The DC vaccine was charactirizated through the mixed lymphocyte responses and cell killing experiment in vitro. Level of interferon-γ (IFN-γ) in the supernatant was checked by ELISA. Results: After stimulation of lysate of glioma stem cell, expression of surface molecules of DC was up-regulated, including CD80, CD86, CD11C and MHC-II. DCs pulsed with lysate of glioma stem cells were more effective than the control group in stimulating original glioma cells-specific cytotoxic T lymphocytes responses, killing glioma cells and boosting the secretion of IFN-γ in vitro. Conclusion: The results demonstrated DCs loaded with antigens derived from glioma stem cells can effectively stimulate naive T cells to form specific cytotoxic T cells, kill glioma cells cultured in vitro.
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Fang, Xiangpeng,Guo, Xianwei,Mao, Ya,Hua, Chunxiu,Shen, Lanyao,Hu, Yongsheng,Wang, Zhaoxiang,Wu, Feng,Chen, Liquan Wiley-VCH 2012 Chemistry, an Asian journal Vol.7 No.5
<P>The most-popular strategy to improve the cycling stability and rate performance of the sulfur electrode in lithium-sulfur (Li-S) batteries is to astrict the sulfur in a conducting medium by using complicated chemical/physical processing. Lithium sulfide (Li(2)S) has been proposed as an alternative electrode material to sulfur. However, for its application, it must meet challenges such as high instability in air together with all of the drawbacks of a sulfur-containing electrode. Herein, we report the feasibility of using Li(2)S, which was obtained by electrochemical conversion of commercial molybdenum disulfide (MoS(2)) into Li(2)S and metallic molybdenium (Mo) at low voltages, as a high-performance active material in Li-S batteries. Metallic Mo prevented the dissolution of lithium polysulfides into the electrolyte and enhanced the conductivity of the sulfide electrode. Therefore, the in situ electrochemically prepared Li(2)S/Mo composite exhibited both high cycling stability and high sulfur utilization.</P>
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