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- 저자 : Lacatus, Monica (검색결과 2 건)
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Laura Dudus,Corina Minciuna,Stefan Tudor,Monica Lacatus,Bogdan Stefan Vasile,Catalin Vasilescu 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.2
Objective: To acknowledge that minimally invasive pelvic exenteration is a feasible alternativeto open surger y and potentially identif y prediction factors for patient outcome. Methods: The study was designed as a retrospective single team analysis of 12 consecutivecases, set between Januar y 2008 and Januar y 2022. Results: Six anterior and 6 total pelvic exenterations were performed. A 75% of caseswere treated using a robotic approach. In 4 cases, an ileal conduit was used for urinar yreconstruction. Mean operative time was 360±30.7 minutes. for anterior pelvic exenterationsand 440±40.7 minutes. for total pelvic exenterations and mean blood loss was 350±35 mL. AnR0 resection was performed in 9 cases (75%) and peri-operative morbidity was 16.6%, withno deaths recorded. Median disease-free sur vival was 12 months (10–14) and overall sur vival(OS) was 20 months (1–127). In terms of OS, 50% of patients were still alive 24 monthsafter surger y. Taking into consideration the follow up period,16.6% of females under 50 orabove 70 years old did not reach the cut off and 4 out of 6 patients that failed to reach it werediagnosed with distant metastases or local recurrence (p=0.169). Conclusion: Our experience is ver y much consistent with literature in regard to primar y siteof cancer, post-operative complications, R0 resection and sur vival rates. On the other hand,minimally invasive approach and urinar y reconstruction type were in contrast with citedpublications. Minimally invasive pelvic exenteration is indeed a safe and feasible procedure,providing patients selection is appropriately performed.
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Martiniuc, Alexandru,Dumitrascu, Traian,Ionescu, Mihnea,Tudor, Stefan,Lacatus, Monica,Herlea, Vlad,Vasilescu, Catalin The Korean Gastric Cancer Association 2021 Journal of gastric cancer Vol.21 No.1
Purpose: Incidence, risk factors, and clinical consequences of pancreatic fistula (POPF) after D1+/D2 radical gastrectomy have not been well investigated in Western patients, particularly those from Eastern Europe. Materials and Methods: A total of 358 D1+/D2 radical gastrectomies were performed by surgeons with high caseloads in a single surgical center from 2002 to 2017. A retrospective analysis of data that were prospectively gathered in an electronic database was performed. POPF was defined and graded according to the International Study Group for Pancreatic Surgery (ISGPS) criteria. Uni- and multivariate analyses were performed to identify potential predictors of POPF. Additionally, the impact of POPF on early complications and long-term outcomes were investigated. Results: POPF was observed in 20 patients (5.6%), according to the updated ISGPS grading system. Cardiovascular comorbidities emerged as the single independent predictor of POPF formation (risk ratio, 3.051; 95% confidence interval, 1.161-8.019; P=0.024). POPF occurrence was associated with statistically significant increased rates of postoperative hemorrhage requiring re-laparotomy (P=0.029), anastomotic leak (P=0.002), 90-day mortality (P=0.036), and prolonged hospital stay (P<0.001). The long-term survival of patients with gastric adenocarcinoma was not affected by POPF (P=0.661). Conclusions: In this large series of Eastern European patients, the clinically relevant rate of POPF after D1+/D2 radical gastrectomy was low. The presence of co-existing cardiovascular disease favored the occurrence of POPF and was associated with an increased risk of postoperative bleeding, anastomotic leak, 90-day mortality, and prolonged hospital stay. POPF was not found to affect the long-term survival of patients with gastric adenocarcinoma.
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