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Anti-tumor Promoting Activity of Some Malaysian Traditional Vegetables (Ulam)
L. Yang Mooi,A. M. Ali,A. B. Norhanom,K. Mat Salleh,A. Murakami,K. Koshimizu 한국생약학회 1999 Natural Product Sciences Vol.5 No.1
Ethanolic extracts of different parts of 10 loyal traditional vegetables (ulam) (Amarunthus gangeticus, Jussiaea linifolia, Eugenic polyantha, Trapa incisca, Trichosanthes anquina, Mangifera indica, Pachyrrhirus erosus, Barringtonia mcarostachya, Carica papaya, and Coleus tuberosus) were screened for in vitro anti-tumor promoting activity using the inhibition test of Epstein-Barr virus (EBV) activation in Raji cells induced by phorbol 12-myristate 13-acetate and sodium-n-butyrate. All the extracts were found to have strong inhibition activity toward EBV-activation, except for leaf extract of T. anquina. The extracts were non-cytotoxic to the Raji cells except for the extracts of A. gangeticus (leaves), B. mucrostachya (leaves), E. polyuntha (young leaves), and J. linifolia (leaves) where the viability of the cells were decreased significantly.