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- 저자 : Kurata Shinji (검색결과 3 건)
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Terumi Ayuse,Shinji Kurata,Gaku Mishima,Mizuki Tachi,Erika Suzue,Kensuke Kiriishi,Yu Ozaki-Honda,Takao Ayuse 대한치과마취과학회 2023 Journal of Dental Anesthesia and Pain Medicine Vol.23 No.2
General anesthesia may influence the postoperative sleep cycle; however, no clinical studies have fully evaluated whether anesthesia causes sleep disturbances during the postoperative period. In this scoping review, we explored the changes in postoperative sleep cycles during surgical procedures or dental treatment under general anesthesia. We compared and evaluated the influence of general anesthesia on sleep cycles and sleep disturbances during the postoperative period in adult and pediatric patients undergoing surgery and/or dental treatment. Literature was retrieved by searching eight public databases. Randomized clinical trials, observational studies, observational case-control studies, and cohort studies were included. Primary outcomes included the incidence of sleep, circadian cycle alterations, and/or sleep disturbances. The search strategy yielded six studies after duplicates were removed. Finally, six clinical trials with 1,044 patients were included. In conclusion, general anesthesia may cause sleep disturbances based on alterations in sleep or the circadian cycle in the postoperative period in patients scheduled for elective surgery.
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Sanuki, Takuro,Mishima, Gaku,Kurata, Shinji,Watanabe, Toshihiro,Kiriishi, Kensuke,Tachi, Mizuki,Ozaki, Yu,Okayasu, Ichiro,Kawai, Mari,Matsushita, Yuki,Miura, Keiichiro,Ayuse, Takao The Korean Dental Society of Anesthsiology 2015 Journal of Dental Anesthesia and Pain Medicine Vol.15 No.3
Background: We hypothesized that ketamine, when administered as the anesthetic induction agent, may prevent cardiovascular depression during high-dose remifentanil administration, unlike propofol. To test our hypothesis, we retrospectively compared the hemodynamic effects of ketamine, during high-dose remifentanil administration, with those of propofol. Methods: Thirty-eight patients who underwent oral surgery at the Nagasaki University Hospital between April 2014 and June 2015 were included in this study. Anesthesia was induced by the following procedure: First, high-dose remifentanil ($0.3-0.5{\mu}g/kg/min$) was administered 2-3 min before anesthesia induction;next, the anesthetic induction agent, either propofol (Group P) or ketamine (Group K), was administered. Mean arterial pressure (MAP) and the heart rate were recorded by the automated anesthesia recording system at four time points: immediately before the administration of high-dose remifentanil (T1);immediately before the administration of propofol or ketamine (T2);2.5 min (T3), and 5 min (T4) after the administration of the anesthetic induction agent. Results: In Group P, the MAP at T3 ($75.7{\pm}15.5mmHg$, P = 0.0015) and T4 ($68.3{\pm}12.5mmHg$, P < 0.001) were significantly lower than those at T1 ($94.0{\pm}12.4mmHg$). However, the MAP values in the K group were very similar (P = 0.133) at all time points. The heart rates in both Groups P (P = 0.254) and K (P = 0.859) remained unchanged over time. Conclusions: We showed that ketamine, when administered as the anesthetic induction agent during high-dose remifentanil administration, prevents cardiovascular depression.
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Okayasu Ichiro,Mizuki Tachi,Sanuki Takuro,Kurata Shinji,Ayuse Takao 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.2
Goreisan might be a medicine to cure the pain caused by thirst and dry mouth symptom of glossodynia. All registered patients were treated with Goreisan by taking 7.5 g / day (min 3) for 2 weeks. Self-filled Visual Analogue Scale (VAS) and tongue perception test by nomo-filament. Furthermore, daily self-filled VAS evaluation was required patients’ home for two weeks during Goreisan administration. There was 57% of patients (8/14) showed “improved” after administration of 2 weeks Goreisan administration based on the criteria of 20% reduction of VAS compared to baseline. Self-filled VAS score was significant low (p = 0.006) at 2 weeks evaluation at second visit and remained lower level through 4 week observation periods compared to baseline value. QST significantly increased after 2 weeks administration of Goreisan (p = 0.008) and remained higher level through 4 week observation periods compared to baseline value. There was significant reduction of daily self-filled VAS patients’ home at day 3 and day 13 ~ day 14. (p < 0.05). There is a weak positive and negative correla-tion between Barometric pressure (hPa) and self-filled VAS scale (cm) in each patients. The administration of Goreisan for two weeks lead to significant reduction of pain perception based on the evaluation of Self-filled pain scale (VAS) and tongue perception test (QST). There is correlation between barometric pressure and self-filled VAS scale. This fact might indicate that Goreisan would be the alternative treatment for glossodynia patients. Goreisan would be a successful alternative treat-ment modality forglossodynia patients.Trial registration Current Controlled trials was registered with the UMIN Clinical TrialsRegistry (identifier: UMIN000035965, 02.21.2019).
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