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Dutta, Tanushree,Kim, Ki-Hyun,Deep, Akash,Szulejko, Jan E.,Vellingiri, Kowsalya,Kumar, Sandeep,Kwon, Eilhann E.,Yun, Seong-Taek Elsevier 2018 RENEWABLE & SUSTAINABLE ENERGY REVIEWS Vol.82 No.3
<P><B>Abstract</B></P> <P>Recycling battery and electronic wastes for the recovery of nanomaterials (NMs) has ushered in a new era in nanotechnology and environmental research. Essentially, NM recycling offers a two-way method of environmental remediation. The potential economic benefits of high-value NM end-products are conducive for industrial scale operations. Simultaneously, it reduces the industrial consumption of finite primary resources. The added benefits of abating environmental pollution (e.g., from VOCs, VFAs, SO<SUB>2</SUB>, NOx, and heavy metals) further contributes to the significance of ongoing research in this particular area. However, some challenges still persist due to the lack of motivation for recycling and the problem of the limited usability (or low stability) of many of the end-products. In this study, we aimed to evaluate different basic aspects of waste recycling in relation to NM recovery, along with other associated techniques. The utility of recovered NMs and potential options for NM recovery are described as highlighting features to help construct a future roadmap for this emerging scientific field. In addition, an assessment of the potential economic returns from recycling high-purity NMs is provided. Outcomes of this review may fuel further innovations for optimizing the current recycling methods for the efficient synthesis of commercial-grade, high purity NMs at minimal cost.</P>
Walekar, Laxman,Dutta, Tanushree,Kumar, Pawan,Ok, Yong Sik,Pawar, Samadhan,Deep, Akash,Kim, Ki-Hyun Elsevier 2017 Trends in analytical chemistry Vol.97 No.-
<P>Quantitation of environmental pollutants has gained momentum due to its widespread requirement in the fields of clinical research, occupational hygiene, public health, and societal welfare. The use of functionalized fluorescent nanomaterials (FFNMs: e.g., metal nanoparticles, semiconductor quantum dots, carbon dots, nanotubes, and nanocrystals) has opened a new avenue for creating simple, selective, and non-invasive real-time analysis, as they can satisfy the growing demand for rapid and costeffective quantitation. Here, we discuss novel strategies for the qualitative and quantitative analysis of a variety of organic and inorganic environmental pollutants by detecting changes in photo-physical or optical properties (e.g., fluorescence, absorbance, and color) of FFNMs used as probes. Particularly, we emphasize potential approaches for the synthesis and characterization of FFNMs and their underlying interactions with environmental pollutants. The simplification of design and enhancement of specificity towards target analytes should be pursued further to upgrade their real-world applicability in diverse fields. (C) 2017 Elsevier B.V. All rights reserved.</P>
Manoj Gupta,Partha Sarathi Choudhury,Sudhir Rawal,G. Karthikeyan,Vineet Talwar,Kumar Deep Dutta,Amitabh Singh 대한핵의학회 2019 핵의학 분자영상 Vol.53 No.6
Purpose The aimof this study was to evaluate safety and therapeutic efficacy of lutetium 177 prostate-specific membrane antigen (Lu-177-PSMA) in metastatic castration-resistant prostate cancer (mCRPC) patients with low performance status. Methods Twenty-two patients already treated with anti-androgens and docetaxel were enrolled for one cycle of Lu-177-PSMA therapy. Haemoglobin, total leukocyte counts, platelets and serum creatinine for toxicity profile while prostate specific antigen (PSA), Eastern Cooperative Oncology Group (ECOG) performance status, visual analogue scale (VAS) and analgesic quantification scale (AQS) for therapeutic efficacy were recorded pre and 8 weeks post therapy.Wilcoxon signed-rank and ANOVA tests were used for statistical analysis. Results Partial response (PR), stable disease (SD) and progressive disease (PD) for PSAwere seen in 5 (22.7%), 13 (59.1%) and 4 (18.2%) patients respectively treated with mean 6.88 GBq dose of Lu-177-PSMA. 8/22 (36.4%) patients showed ≥ 30% drop in PSA. Grade 3 haemoglobin toxicity was seen in 5/22 (22.7%) patients. No patient developed grade 4 haemoglobin toxicity. No patients had grade 3 or 4 leukocytopenia or thrombocytopenia. Wilcoxon signed-rank test showed statistical significant (P < 0.05) difference in pre and post treatment ECOG, VAS, and AQS scores. The ANOVA test showed statistically significant difference in mean doses of Lu-177-PSMA used in three PSA response groups while difference was non-significant for other variables. Conclusion We concluded that Lu-177-PSMA therapy has adequate pain palliation in end-stage mCRPC patients with low performance status and it has a potential to become effective therapeutic option in properly selected patients.