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- 저자 : Kui Zhao (검색결과 38 건)
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Zhan-Kui Zhao,Hong-Lian Yu,Fei Xiao,Shi-Wen Li,Wen-Biao Liao,Kai-Liang Zhao 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.3
We assessed the ability of muscle-derived stem cells (MDSC) to differentiate into smooth muscle cells (SMC) and their potential to promote the regeneration of smooth muscle with a vessel extracellular matrix (VECM)for tissue engineering of the ureter. MDSC were isolated,proliferated, and identified by flow cytometry. SMC phenotype differentiation was induced with a smooth muscle induction medium. Gene expression was evaluated by real-time quantitative polymerase chain reaction (PCR)and Western blot studies. The VECM was obtained by a decellularization process, and cytotoxic effects were evaluated by exposing the induced cells to a VECM extract. The induced cells were seeded onto VECM in vitro for 1 week, and then the compound grafts were used for ureter reconstitution in vivo. The grafts were obtained for histological studies at 2, 4, 8, and 16 weeks post-operation. Intravenous urography was used to evaluate renal function and ureteral patency. Flow cytometry demonstrated that the MDSC expressed Sca-1 and desmin, but did not express CD45. After induction, SMC phenotype gene expression was confirmed in the induced cells by real-time quantitative PCR and Western blot studies. VECM exhibited a nontoxic effect on the induced cells in vitro. At 16 weeks postoperation,a histological evaluation showed that multilayered urothelium and organized muscle fiber bundles had formed in the grafts. Intravenous urography demonstrated no evidence of ureteral stricture or hydroureteronephrosis. These results demonstrate that MDSC can be induced into SMC and that this was useful for promoting regeneration of smooth muscles for ureter tissue engineering. We assessed the ability of muscle-derived stem cells (MDSC) to differentiate into smooth muscle cells (SMC) and their potential to promote the regeneration of smooth muscle with a vessel extracellular matrix (VECM)for tissue engineering of the ureter. MDSC were isolated,proliferated, and identified by flow cytometry. SMC phenotype differentiation was induced with a smooth muscle induction medium. Gene expression was evaluated by real-time quantitative polymerase chain reaction (PCR)and Western blot studies. The VECM was obtained by a decellularization process, and cytotoxic effects were evaluated by exposing the induced cells to a VECM extract. The induced cells were seeded onto VECM in vitro for 1 week, and then the compound grafts were used for ureter reconstitution in vivo. The grafts were obtained for histological studies at 2, 4, 8, and 16 weeks post-operation. Intravenous urography was used to evaluate renal function and ureteral patency. Flow cytometry demonstrated that the MDSC expressed Sca-1 and desmin, but did not express CD45. After induction, SMC phenotype gene expression was confirmed in the induced cells by real-time quantitative PCR and Western blot studies. VECM exhibited a nontoxic effect on the induced cells in vitro. At 16 weeks postoperation,a histological evaluation showed that multilayered urothelium and organized muscle fiber bundles had formed in the grafts. Intravenous urography demonstrated no evidence of ureteral stricture or hydroureteronephrosis. These results demonstrate that MDSC can be induced into SMC and that this was useful for promoting regeneration of smooth muscles for ureter tissue engineering.
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On overrings of Gorenstein Dedekind domains
Kui Hu,Fanggui Wang,Longyu Xu,Songquan Zhao 대한수학회 2013 대한수학회지 Vol.50 No.5
In this paper, we mainly discuss Gorenstein Dedekind domains (G-Dedekind domains for short) and their overrings. Let R be a one-dimensional Noetherian domain with quotient field K and integral closure T. Then it is proved that R is a G-Dedekind domain if and only if for any prime ideal P of R which contains (R:KT), P is Gorenstein projective. We also give not only an example to show that G-Dedekind domains are not necessarily Noetherian Warfield domains, but also a definition for a special kind of domain: a 2-DVR. As an application, we prove that a Noetherian domain R is a Warfield domain if and only if for any maximal ideal M of R, RM is a 2-DVR.
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Kui Wang,Lu Shen,Rong Lu,Zhao Yang,Zongbao Qin 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-
Ultrahigh molecular weight polyethylene (UHMWPE) fibers have an ultralow interfacial property becauseof their extraordinarily smooth and nonpolar surfaces, and this property is a persistent problem inUHMWPE fiber-reinforced composites. In this investigation, a novel one-step and mild strategy forenhancing the interfacial property of UHMWPE fiber-reinforced composites was reported. In this strategy,a biomimetic layer with abundant stacked and three-dimensional nanoparticles formed on fiberssurface through the synergistic effect of polydopamine and 3-aminopropyltriethoxysilane. Owing tothe unique three-dimensional structure and sufficient polar groups on the fibers surface, surface roughnessand surface energy significantly increased, and wettability improved. Consequently, the interfacialshear strength (IFSS) of the fibers exhibited a 407.8% increase (8.36 MPa) relative to that of untreatedUHMWPE (2.05 MPa) because of these synergistic effects. Further analysis indicated that the failuremechanism of the fibers with the highest IFSS was the transformation from adhesive failure to cohesivefailure and substrate failure. The mild preparation process maintained the high crystallinity and orientationof the modified UHMWPE fibers, which exhibited a high tensile force of up to 81 cN.
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Zhao, Tai-Yun,Tu, Jing,Wang, Yin,Cheng, Da-Wei,Gao, Xian-Kui,Luo, Hao,Yan, Bi-Chun,Xu, Xiao-Li,Zhang, Hong-Ling,Lu, Xing-Jun,Wang, Yao-Jun Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.5
Background: Through search the possible randomized control trials, we make a renewed meta-analysis in order to assess the impact of aspirin in preventing the recurrence of colorectal adenoma. Materials and Methods: The Medicine/PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Chinese biomedical literature service system (SinoMed) databases were searched for the related randomized controlled trials until to the April 2016. Three different authors respectively evaluated the quality of studies and extracted data, and we used the STATA software to analyze, investigate heterogeneity between the data, using the fixed-effects model to calculate and merge data. Results: 7 papers were included the renewed meta-analysis, among these studies, two pairs were identified as representing the same study population, with the only difference being the duration of follow-up. Thus there were only five papers included our meta-analysis, and one Chinese paper were also included the work. Results were categorized by the length of follow-up, different kinds of people, varied dose of oral aspirin. The relative of adenoma in patients taking aspirin vs placebo were 0.73 (95% CI 0.55-0.98, P=0.039) with 1 year follow up; 0.84 (95% CI 0.72-0.98, P=0.484) with greater than 1 year follow up; for the advanced adenoma, the RR 0.68 (95% CI 0.49-0.94, P=0.582),for one year; RR=0.75 (95% CI 0.52-1.07, P=0.552) for greater one year. Furthermore the white population could divided into two subgroups according to the different length of follow-up time. When the length of follow-up time less than 3-year, The RR of two subgroups respective were RR=0.86 (95% CI 0.76-0.98, P=0.332), $I^2=0%$, RR=0.68 (95% CI 0.47-0.98, P=0.552), $I^2=64.6%$, But with the extension of follow-up time greater than 2-year, with the white, oral aspirin without considering dose had no efficacy on preventing the recurrence of any adenoma, the RR was 0.86 (95% CI 0.71-1.05, P=0.302), $I^2=16.4%$. Conclusions: This meta-analysis indicated that oral aspirin is associated with a remarkable decrease in the recurrence of any adenoma and advanced adenomas in patients follow-up for 1 year without concerning the dose of aspirin, but with the extension of follow-up time for greater than 1 year, oral aspirin can be effective on preventing the recurrence of any adenoma, but for the advanced adenoma, the result indicated that oral aspirin had no efficacy, According to the inclusion of ethnic groups, we also divided relevant papers into two subgroups as the yellow and white group. Then the follow-up time was less than 3 years, oral aspirin without considering the dose, had an significant efficacy on preventing the recurrence of any adenoma. But with the follow-up greater than 2 years, oral aspirin had no effect in the white.
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ON OVERRINGS OF GORENSTEIN DEDEKIND DOMAINS
Hu, Kui,Wang, Fanggui,Xu, Longyu,Zhao, Songquan Korean Mathematical Society 2013 대한수학회지 Vol.50 No.5
In this paper, we mainly discuss Gorenstein Dedekind do-mains (G-Dedekind domains for short) and their overrings. Let R be a one-dimensional Noetherian domain with quotient field K and integral closure T. Then it is proved that R is a G-Dedekind domain if and only if for any prime ideal P of R which contains ($R\;:_K\;T$), P is Gorenstein projective. We also give not only an example to show that G-Dedekind domains are not necessarily Noetherian Warfield domains, but also a definition for a special kind of domain: a 2-DVR. As an application, we prove that a Noetherian domain R is a Warfield domain if and only if for any maximal ideal M of R, $R_M$ is a 2-DVR.
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Hui Zhao,Kui-Can Li,Wei Wu,Qing Li,Yan Jiang,Bing-Xu Cheng,Chong-Xing Huang,Hua-Nan Li 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-
Cellulose nanofiber (CNF) has been widely used to reinforce the mechanical properties of waterbornepolyurethane (WPU). There are, however, few works that focus on structure, rheological behavior, andcreep resistance of WPU/CNF composites. To fill this research gap, in this work, the m-CNF was obtainedby c-aminopropyltriethoxysilane modification to improve the interfacial strength of CNF and WPU, andthen it was introduced into the polyurethane matrix. Structure characterization of WPU/m-CNFnanocomposites is performed using Fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction(XRD), Scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The obtainedresults show that with the increase of m-CNF, the hydrogen bonding index (HBI) increased, which meanta significant improvement in the mechanical properties. The tensile strength improved by 480%. Moreover, with the increase of m-CNF content, the viscosity, storage modulus, and loss modulus of thedispersions increased and showed more obvious shear-thinning behavior. In addition, m-CNF improvedthe thermal stability and creep resistance of WPU. The creep strain of WPU decreased from 3% to 0.2%. This work offers a simply feasible way to prepare environmental friendly green nanocomposites.
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Guo, Wei,Zhao, Qiao-sheng,Tian, Yu-kui,Zhang, Wan-chao The Society of Naval Architects of Korea 2020 International Journal of Naval Architecture and Oc Vol.12 No.1
This paper presents the virtual mass method to implement the prediction of total resistance for ice-going ship in floe ice region based on the combined method of CFD and DEM. Two ways of floe ice distribution are adopted for the analysis and comparison. The synthetic ice model test has been conducted to determine the optimal virtual mass coefficients for the two different floe ice distributions. Moreover, the further verification and prediction are developed in different ice conditions. The results show that, the fixed and random distributions in numerical method can simulate the interaction of ship and ice vividly, the trend of total resistance varying with the speed and ice concentration obtained by the numerical simulation is consistent with the model test. The random distribution of floe ice has higher similarity and better accuracy than fixed distribution.
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Guo, Wei,Zhao, Qiao-sheng,Tian, Yu-kui,Zhang, Wan-chao The Society of Naval Architects of Korea 2020 International Journal of Naval Architecture and Oc Vol.12 No.-
This paper presents the virtual mass method to implement the prediction of total resistance for ice-going ship in floe ice region based on the combined method of CFD and DEM. Two ways of floe ice distribution are adopted for the analysis and comparison. The synthetic ice model test has been conducted to determine the optimal virtual mass coefficients for the two different floe ice distributions. Moreover, the further verification and prediction are developed in different ice conditions. The results show that, the fixed and random distributions in numerical method can simulate the interaction of ship and ice vividly, the trend of total resistance varying with the speed and ice concentration obtained by the numerical simulation is consistent with the model test. The random distribution of floe ice has higher similarity and better accuracy than fixed distribution.
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